WormBase Tree Display for Gene: WBGene00011597
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| WBGene00011597 | SMap | S_parent | Sequence | T07G12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | zim-1 | Person_evidence | WBPerson136 | |||||
| Sequence_name | T07G12.6 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_T07G12.6 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | zim-1 | ||||||||
| DB_info | Database | AceView | gene | 4L321 | |||||
| WormQTL | gene | WBGene00011597 | |||||||
| WormFlux | gene | WBGene00011597 | |||||||
| NDB | locus_tag | CELE_T07G12.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011597|UniProtKB=B2MZC6 | |||||||
| family | PTHR36945 | ||||||||
| NCBI | gene | 3565259 | |||||||
| RefSeq | protein | NM_001276847.3 | |||||||
| NM_001276848.3 | |||||||||
| NM_069547.5 | |||||||||
| NM_001136397.5 | |||||||||
| TREEFAM | TREEFAM_ID | TF319120 | |||||||
| TrEMBL | UniProtAcc | I2HAK0 | |||||||
| O18064 | |||||||||
| B2MZC6 | |||||||||
| J3JZZ7 | |||||||||
| UniProt_GCRP | UniProtAcc | B2MZC6 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 28 Jul 2005 14:54:34 | WBPerson1983 | Event | Acquires_merge | WBGene00011603 | ||||
| Name_change | CGC_name | zim-1 | |||||||
| Acquires_merge | WBGene00011603 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zim | ||||||||
| Allele (99) | |||||||||
| Strain | WBStrain00004046 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00005919 | ||||||||
| 00005920 | |||||||||
| 00005921 | |||||||||
| Contained_in_operon | CEOP4384 | ||||||||
| Ortholog (23) | |||||||||
| Paralog | WBGene00001867 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00011601 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00011600 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015352 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | zim-1 encodes a protein with two C-terminal noncanonical C2H2zinc-fingers whose paralogs include HIM-8, ZIM-2/-3, and C02F5.12; ZIM-1specifically required for homolog pairing, synapsis, and segregation ofchromosomes II and III during meiosis; zim-1(tm1813) oocytes endingprophase have ~4 bivalents and ~4 univalents, the latter of which areconsistently chromosomes II and III; ZIM-1 associates with the left endsof chromosomes II and III, which may indicate an association with theirpairing centers; while the C-terminal region of ZIM-1 most closelyresembles those of its orthologs in other Caenorhabditis species, itsN-terminal region instead most closely resembles those of its paralogsin C. elegans, indicating coevolving, species-specific functions; ZIM-1foci, like HIM-8 foci, associate with the nuclear envelope duringmeiotic prophase; zim-1 mutants also have some defective segregation ofthe X chromosome (yielding a Him phenotype), but this may be an indirecteffect of autosomal asynapsis. | Paper_evidence | WBPaper00026985 | |||||
| WBPaper00028860 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 22 Mar 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in meiotic chromosome segregation. Located in condensed nuclear chromosome. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T07G12.6a | |||||||
| T07G12.6b | |||||||||
| T07G12.6c | |||||||||
| T07G12.6d | |||||||||
| Corresponding_CDS_history | T07G12.6:wp146 | ||||||||
| Corresponding_transcript | T07G12.6a.1 | ||||||||
| T07G12.6b.1 | |||||||||
| T07G12.6c.1 | |||||||||
| T07G12.6d.1 | |||||||||
| Associated_feature | WBsf660589 | ||||||||
| WBsf1018108 | |||||||||
| Transcription_factor | WBTranscriptionFactor000914 | ||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr4560 | ||||||||
| Expr1029120 | |||||||||
| Expr1035111 | |||||||||
| Expr1156396 | |||||||||
| Expr2018149 | |||||||||
| Expr2036286 | |||||||||
| Antibody | WBAntibody00001188 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (97) | |||||||||
| SAGE_tag | SAGE:tgcaaaggaa | Strand | Sense | ||||||
| Unambiguously_mapped | |||||||||
| SAGE:taatcacaaa | Strand | Antisense | |||||||
| SAGE:agacacaatttacaaaa | Strand | Antisense | |||||||
| SAGE:agacacaatt | Strand | Antisense | |||||||
| SAGE:gatctggtaccgattca | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| Interaction (295) | |||||||||
| Map_info | Map | IV | Position | 4.61848 | Error | 0.001601 | |||
| Positive | Positive_clone | T07G12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5415 | |||||||
| 5421 | |||||||||
| 4720 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (30) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
