WormBase Tree Display for Gene: WBGene00009126
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| WBGene00009126 | SMap | S_parent | Sequence | F25H5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pyk-1 | Person_evidence | WBPerson360 | |||||
| Sequence_name | F25H5.3 | ||||||||
| Molecular_name (16) | |||||||||
| Other_name | CELE_F25H5.3 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | pyk-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 16 Jul 2009 12:31:02 | WBPerson9133 | Name_change | CGC_name | pyk-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pyk | ||||||||
| Allele (93) | |||||||||
| Strain | WBStrain00001531 | ||||||||
| WBStrain00036461 | |||||||||
| WBStrain00037832 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP1983 | ||||||||
| Ortholog (56) | |||||||||
| Paralog | WBGene00014001 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pyk-1 encodes one of two C. elegans pyruvate kinases; large-scale RNAi experiments indicate that pyk-1 is essential for embryonic development and specifically, for normal cortical activity in the AB blastomere; large-scale expression studies show that pyk-1 is expressed in body wall muscle in larvae and in body wall and vulval muscle, as well as in the reproductive system, in adults. | Paper_evidence | WBPaper00024497 | |||||
| WBPaper00025054 | |||||||||
| WBPaper00031006 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 16 Jul 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable pyruvate kinase activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including Gaucher's disease; pyruvate kinase deficiency of red cells; and type 2 diabetes mellitus. Is an ortholog of human PKM (pyruvate kinase M1/2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1926 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9020) | ||||
| DOID:0111077 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9020) | ||||||
| DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9020) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9020) | ||||||
| DOID:2861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9020) | ||||||
| Molecular_info | Corresponding_CDS | F25H5.3a | |||||||
| F25H5.3b | |||||||||
| F25H5.3c | |||||||||
| F25H5.3d | |||||||||
| F25H5.3e | |||||||||
| Corresponding_transcript | F25H5.3a.1 | ||||||||
| F25H5.3b.1 | |||||||||
| F25H5.3c.1 | |||||||||
| F25H5.3c.2 | |||||||||
| F25H5.3d.1 | |||||||||
| F25H5.3e.1 | |||||||||
| Other_sequence (174) | |||||||||
| Associated_feature (24) | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Chronogram905 | ||||||||
| Chronogram1189 | |||||||||
| Expr5864 | |||||||||
| Expr1016829 | |||||||||
| Expr1033976 | |||||||||
| Expr1149463 | |||||||||
| Expr2015203 | |||||||||
| Expr2033437 | |||||||||
| Drives_construct | WBCnstr00002380 | ||||||||
| WBCnstr00032444 | |||||||||
| Construct_product | WBCnstr00032444 | ||||||||
| Microarray_results (42) | |||||||||
| Expression_cluster (162) | |||||||||
| Interaction (114) | |||||||||
| Map_info | Map | I | Position | 3.64454 | Error | 0.005321 | |||
| Positive | Positive_clone | F25H5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
