WormBase Tree Display for Gene: WBGene00008911

WBGene00008911 SMap: S_parent: Sequence: F17C8
  Identity: Version: 1
    Name: Sequence_name: F17C8.6
      Molecular_name: F17C8.6
        F17C8.6.1
        CE00960
      Other_name: CELE_F17C8.6 Accession_evidence: NDB BX284603
      Public_name: F17C8.6
    DB_info: Database: AceView gene 3F834
        WormQTL gene WBGene00008911
        WormFlux gene WBGene00008911
        NDB locus_tag CELE_F17C8.6
        Panther gene CAEEL|WormBase=WBGene00008911|UniProtKB=Q19526
          family PTHR46141
        NCBI gene 175626
        RefSeq protein NM_065573.2
        TrEMBL UniProtAcc Q19526
        UniProt_GCRP UniProtAcc Q19526
        OMIM gene 611549
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (15)
    RNASeq_FPKM (74)
    GO_annotation: 00065005
      00116725
    Ortholog (35)
    Paralog: WBGene00000367 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00001187 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003558 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006742 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006809 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: F17C8.6 encodes an alpha1 Ca2+ channel subunit; large-scale RNAi experiments indicate that during development F17C8.6, along with nca-2, may play a role in regulating egg size and shape. Paper_evidence: WBPaper00025054
          Curator_confirmed: WBPerson1843
          Date_last_updated: 12 Jun 2007 00:00:00
      Automated_description: Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Human ortholog(s) of this gene implicated in congenital limbs-face contractures-hypotonia-developmental delay syndrome. Is an ortholog of human NALCN (sodium leak channel, non-selective). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: EFO:MONDO:0014176 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19082)
      DOID:0081048 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19082)
  Molecular_info: Corresponding_CDS: F17C8.6
    Corresponding_transcript: F17C8.6.1
    Other_sequence: JO469564.1
    Associated_feature: WBsf650996
      WBsf992205
      WBsf1014799
      WBsf226569
  Experimental_info: RNAi_result: WBRNAi00041360 Inferred_automatically: RNAi_primary
      WBRNAi00082652 Inferred_automatically: RNAi_primary
      WBRNAi00005231 Inferred_automatically: RNAi_primary
      WBRNAi00005088 Inferred_automatically: RNAi_primary
      WBRNAi00011267 Inferred_automatically: RNAi_primary
      WBRNAi00044887 Inferred_automatically: RNAi_primary
      WBRNAi00013467 Inferred_automatically: RNAi_primary
      WBRNAi00082556 Inferred_automatically: RNAi_primary
      WBRNAi00031074 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023602
      Expr1148853
    Drives_construct: WBCnstr00032601
    Construct_product: WBCnstr00032601
    Microarray_results (20)
    Expression_cluster (47)
    Interaction: WBInteraction000194654
  Map_info: Positive: Positive_clone: F17C8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -2.60804
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene