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WormBase Tree Display for Gene: WBGene00007942

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Name Class

WBGene00007942SMapS_parentSequenceC34F6
IdentityVersion2
NameCGC_nameidh-2Person_evidenceWBPerson261
Sequence_nameC34F6.8
Molecular_nameC34F6.8
C34F6.8.1
CE15677
Other_nameCELE_C34F6.8Accession_evidenceNDBBX284606
Public_nameidh-2
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Oct 2008 10:23:18WBPerson2970Name_changeCGC_nameidh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classidh
Allele (39)
StrainWBStrain00033023
WBStrain00033024
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (36)
ParalogWBGene00010317Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionidh-2 encodes a predicted mitochondrial isocitrate dehydrogenase; by homology, IDH-2 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate as part of the citric acid cycle.Curator_confirmedWBPerson1843
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionPredicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including D-2-hydroxyglutaric aciduria 2; gastrointestinal system cancer (multiple); and lung non-small cell carcinoma (multiple). Is an ortholog of human IDH2 (isocitrate dehydrogenase (NADP(+)) 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (11)
Molecular_infoCorresponding_CDSC34F6.8
Corresponding_transcriptC34F6.8.1
Other_sequence (83)
Associated_featureWBsf648525
WBsf648526
WBsf655211
WBsf1006935
WBsf236360
Experimental_infoRNAi_resultWBRNAi00029550Inferred_automaticallyRNAi_primary
WBRNAi00000895Inferred_automaticallyRNAi_primary
WBRNAi00011628Inferred_automaticallyRNAi_primary
WBRNAi00041925Inferred_automaticallyRNAi_primary
Expr_patternExpr1021924
Expr1033448
Expr1145932
Expr2012670
Expr2030906
Drives_constructWBCnstr00033366
Construct_productWBCnstr00033366
Microarray_results (21)
Expression_cluster (131)
Interaction (44)
Map_infoMapXPosition2.86353Error0.000584
PositivePositive_cloneC34F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027145
WBPaper00038491
WBPaper00051770
WBPaper00055090
WBPaper00059575
WBPaper00064707
WBPaper00065625
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene