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WormBase Tree Display for Gene: WBGene00010317

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Name Class

WBGene00010317SMapS_parentSequenceF59B8
IdentityVersion2
NameCGC_nameidh-1Person_evidenceWBPerson261
Sequence_nameF59B8.2
Molecular_nameF59B8.2a
F59B8.2a.1
CE03436
F59B8.2b
CE47303
F59B8.2c
CE47163
F59B8.2b.1
F59B8.2c.1
Other_nameCELE_F59B8.2Accession_evidenceNDBBX284604
Public_nameidh-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Oct 2008 10:23:18WBPerson2970Name_changeCGC_nameidh-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classidh
Allele (27)
StrainWBStrain00003527
WBStrain00002807
WBStrain00032810
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (38)
ParalogWBGene00007942Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionidh-1 encodes a predicted cytosolic isocitrate dehydrogenase; by homology, IDH-1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate.Curator_confirmedWBPerson1843
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionPredicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process and isocitrate metabolic process. Predicted to be located in cytosol; mitochondrion; and peroxisome. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and hematologic cancer (multiple). Is an ortholog of human IDH1 (isocitrate dehydrogenase (NADP(+)) 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:5016Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:4928Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3068Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:0050908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3910Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3070Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:3907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:417Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
DOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5382)
Molecular_infoCorresponding_CDSF59B8.2a
F59B8.2b
F59B8.2c
Corresponding_transcriptF59B8.2a.1
F59B8.2b.1
F59B8.2c.1
Other_sequence (57)
Associated_featureWBsf668157
WBsf668158
WBsf981804
WBsf997420
WBsf1017963
WBsf230567
WBsf230568
WBsf230569
Experimental_infoRNAi_resultWBRNAi00090634Inferred_automaticallyRNAi_primary
WBRNAi00080812Inferred_automaticallyRNAi_primary
WBRNAi00065271Inferred_automaticallyRNAi_primary
WBRNAi00016084Inferred_automaticallyRNAi_primary
WBRNAi00001636Inferred_automaticallyRNAi_primary
WBRNAi00033293Inferred_automaticallyRNAi_primary
WBRNAi00049155Inferred_automaticallyRNAi_primary
WBRNAi00113980Inferred_automaticallyRNAi_primary
Expr_patternChronogram1063
Chronogram1718
Expr6263
Expr6264
Expr1018358
Expr1034502
Expr1152898
Expr2012669
Expr2030905
Drives_constructWBCnstr00003334
WBCnstr00004581
WBCnstr00031510
Construct_productWBCnstr00031510
Microarray_results (25)
Expression_cluster (219)
Interaction (103)
Map_infoMapIVPosition4.24582Error0.002337
PositivePositive_cloneF59B8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene