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WormBase Tree Display for Gene: WBGene00007576

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Name Class

WBGene00007576SMapS_parentSequenceC14B1
IdentityVersion2
NameCGC_namedph-1Person_evidenceWBPerson1847
Sequence_nameC14B1.5
Molecular_nameC14B1.5
C14B1.5.1
CE17401
Other_nameCELE_C14B1.5Accession_evidenceNDBBX284603
Public_namedph-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Jan 2009 14:01:14WBPerson2970Name_changeCGC_namedph-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdph
Allele (43)
StrainWBStrain00035549
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP3136
Ortholog (36)
ParalogWBGene00007488Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptiondph-1 encodes an ortholog of S. cerevisiae YIL103 and human DPH2L1/OVCA1 (OMIM:603527, deleted or downregulated in ovarian tumors); DPH-1 is paralogous to S. cerevisiae DPH2/YKL191W, a protein component of diphtamide synthesis.Paper_evidence (11)
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated14 Dec 2009 00:00:00
Automated_descriptionPredicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to contribute to 2-(3-amino-3-carboxypropyl)histidine synthase activity. Predicted to be involved in protein histidyl modification to diphthamide. Predicted to be located in protein-containing complex. Is an ortholog of human DPH1 (diphthamide biosynthesis 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070477Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3003)
Molecular_infoCorresponding_CDSC14B1.5
Corresponding_transcriptC14B1.5.1
Other_sequence (38)
Associated_featureWBsf658766
WBsf991876
WBsf1014618
WBsf224643
Experimental_infoRNAi_resultWBRNAi00111886Inferred_automaticallyRNAi_primary
WBRNAi00040493Inferred_automaticallyRNAi_primary
WBRNAi00028874Inferred_automaticallyRNAi_primary
WBRNAi00010724Inferred_automaticallyRNAi_primary
WBRNAi00006009Inferred_automaticallyRNAi_primary
WBRNAi00068044Inferred_automaticallyRNAi_primary
WBRNAi00106832Inferred_automaticallyRNAi_primary
Expr_patternExpr1018672
Expr1033259
Expr1144561
Expr2011047
Expr2029284
Drives_constructWBCnstr00033638
Construct_productWBCnstr00033638
Microarray_results (19)
Expression_cluster (85)
Interaction (45)
Map_infoMapIIIPosition-4.44099Error0.038633
PositivePositive_cloneC14B1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00041771
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene