WormBase Tree Display for Gene: WBGene00007167
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WBGene00007167 | SMap | S_parent | Sequence | B0393 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | rbg-3 | Person_evidence | WBPerson657 | |||||
Sequence_name | B0393.2 | ||||||||
Molecular_name | B0393.2 | ||||||||
B0393.2.1 | |||||||||
CE00855 | |||||||||
B0393.2.2 | |||||||||
Other_name | tbc-5 | Person_evidence | WBPerson524 | ||||||
WBPerson293 | |||||||||
CELE_B0393.2 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | rbg-3 | ||||||||
DB_info | Database | AceView | gene | 3F845 | |||||
WormQTL | gene | WBGene00007167 | |||||||
WormFlux | gene | WBGene00007167 | |||||||
NDB | locus_tag | CELE_B0393.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00007167|UniProtKB=Q17491 | |||||||
family | PTHR22957 | ||||||||
NCBI | gene | 175629 | |||||||
RefSeq | protein | NM_065578.7 | |||||||
TREEFAM | TREEFAM_ID | TF105784 | |||||||
TrEMBL | UniProtAcc | Q17491 | |||||||
UniProt_GCRP | UniProtAcc | Q17491 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:47 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 14 Sep 2005 10:27:05 | WBPerson2970 | Name_change | CGC_name | rbg-3 | ||||
3 | 23 Jun 2008 18:34:24 | WBPerson2970 | Name_change | Other_name | tbc-5 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rbg | ||||||||
Allele (37) | |||||||||
Component_of_genotype | WBGenotype00000017 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00058275 | ||||||||
00058276 | |||||||||
00058277 | |||||||||
Contained_in_operon | CEOP3866 | ||||||||
Ortholog (34) | |||||||||
Paralog (17) | |||||||||
Structured_description | Concise_description | rbg-3 encodes a predicted TBC domain-containing RabGTPase-activating protein (RabGAP) similar to the Ypt/Rab specific GTPase-activating protein gyp6; YPT/Rab GTPases and GAPs regulate eukaryotic vesicular transport; RBG-3 functions as a GTPase for both human and elegans RAB-7; rbg-3 interacts with tub-1/Tubby in yeast two-hybrid screens and regulates fat storage along with tub-1, but not life span, suggesting that rbg-3 could function in a endocytic pathway as a target of tub-1 for regulation of fat storage; rbg-3 is expressed in the amphid and phasmid neurons in the head and localizes to the cytoplasm, this is similar to the expression pattern of tub-1. | Paper_evidence | WBPaper00026699 | |||||
WBPaper00030935 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 10 Jan 2012 00:00:00 | ||||||||
Automated_description | Enables GTPase activator activity. Located in cytoplasm. Expressed in amphid neurons and phasmid neurons. Used to study obesity. Is an ortholog of human TBC1D5 (TBC1 domain family member 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:9970 | |||||||
Models_disease_asserted | WBDOannot00000027 | ||||||||
Molecular_info | Corresponding_CDS | B0393.2 | |||||||
Corresponding_transcript | B0393.2.1 | ||||||||
B0393.2.2 | |||||||||
Other_sequence (39) | |||||||||
Associated_feature | WBsf645121 | ||||||||
WBsf658858 | |||||||||
WBsf224793 | |||||||||
Experimental_info | RNAi_result | WBRNAi00007603 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00061102 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00005493 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00000354 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00103149 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039007 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00028119 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00009741 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00061101 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr3659 | ||||||||
Expr1020761 | |||||||||
Expr1033083 | |||||||||
Expr1143172 | |||||||||
Expr2015270 | |||||||||
Expr2033504 | |||||||||
Drives_construct | WBCnstr00011579 | ||||||||
WBCnstr00033953 | |||||||||
Construct_product | WBCnstr00011579 | ||||||||
WBCnstr00033953 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (117) | |||||||||
Interaction (104) | |||||||||
WBProcess | WBbiopr:00000121 | ||||||||
Map_info | Map | III | Position | -2.57882 | Error | 0.009833 | |||
Positive | Positive_clone | B0393 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 5500 | |||||||
4625 | |||||||||
Pseudo_map_position | |||||||||
Reference | WBPaper00026147 | ||||||||
WBPaper00026699 | |||||||||
WBPaper00030935 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00043173 | |||||||||
WBPaper00044609 | |||||||||
WBPaper00047687 | |||||||||
WBPaper00051758 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |