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WormBase Tree Display for Gene: WBGene00007167

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Name Class

WBGene00007167SMapS_parentSequenceB0393
IdentityVersion3
NameCGC_namerbg-3Person_evidenceWBPerson657
Sequence_nameB0393.2
Molecular_nameB0393.2
B0393.2.1
CE00855
B0393.2.2
Other_nametbc-5Person_evidenceWBPerson524
WBPerson293
CELE_B0393.2Accession_evidenceNDBBX284603
Public_namerbg-3
DB_infoDatabaseAceViewgene3F845
WormQTLgeneWBGene00007167
WormFluxgeneWBGene00007167
NDBlocus_tagCELE_B0393.2
PanthergeneCAEEL|WormBase=WBGene00007167|UniProtKB=Q17491
familyPTHR22957
NCBIgene175629
RefSeqproteinNM_065578.7
TREEFAMTREEFAM_IDTF105784
TrEMBLUniProtAccQ17491
UniProt_GCRPUniProtAccQ17491
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:47WBPerson1971EventImportedInitial conversion from CDS class of WS125
214 Sep 2005 10:27:05WBPerson2970Name_changeCGC_namerbg-3
323 Jun 2008 18:34:24WBPerson2970Name_changeOther_nametbc-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrbg
Allele (37)
Component_of_genotypeWBGenotype00000017
RNASeq_FPKM (74)
GO_annotation00058275
00058276
00058277
Contained_in_operonCEOP3866
Ortholog (34)
Paralog (17)
Structured_descriptionConcise_descriptionrbg-3 encodes a predicted TBC domain-containing RabGTPase-activating protein (RabGAP) similar to the Ypt/Rab specific GTPase-activating protein gyp6; YPT/Rab GTPases and GAPs regulate eukaryotic vesicular transport; RBG-3 functions as a GTPase for both human and elegans RAB-7; rbg-3 interacts with tub-1/Tubby in yeast two-hybrid screens and regulates fat storage along with tub-1, but not life span, suggesting that rbg-3 could function in a endocytic pathway as a target of tub-1 for regulation of fat storage; rbg-3 is expressed in the amphid and phasmid neurons in the head and localizes to the cytoplasm, this is similar to the expression pattern of tub-1.Paper_evidenceWBPaper00026699
WBPaper00030935
Curator_confirmedWBPerson324
Date_last_updated10 Jan 2012 00:00:00
Automated_descriptionEnables GTPase activator activity. Located in cytoplasm. Expressed in amphid neurons and phasmid neurons. Used to study obesity. Is an ortholog of human TBC1D5 (TBC1 domain family member 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970
Models_disease_assertedWBDOannot00000027
Molecular_infoCorresponding_CDSB0393.2
Corresponding_transcriptB0393.2.1
B0393.2.2
Other_sequence (39)
Associated_featureWBsf645121
WBsf658858
WBsf224793
Experimental_infoRNAi_resultWBRNAi00007603Inferred_automaticallyRNAi_primary
WBRNAi00061102Inferred_automaticallyRNAi_primary
WBRNAi00005493Inferred_automaticallyRNAi_primary
WBRNAi00000354Inferred_automaticallyRNAi_primary
WBRNAi00103149Inferred_automaticallyRNAi_primary
WBRNAi00039007Inferred_automaticallyRNAi_primary
WBRNAi00028119Inferred_automaticallyRNAi_primary
WBRNAi00009741Inferred_automaticallyRNAi_primary
WBRNAi00061101Inferred_automaticallyRNAi_primary
Expr_patternExpr3659
Expr1020761
Expr1033083
Expr1143172
Expr2015270
Expr2033504
Drives_constructWBCnstr00011579
WBCnstr00033953
Construct_productWBCnstr00011579
WBCnstr00033953
Microarray_results (21)
Expression_cluster (117)
InteractionWBInteraction000031865
WBInteraction000159960
WBInteraction000171331
WBInteraction000172075
WBInteraction000172699
WBInteraction000177926
WBInteraction000186025
WBInteraction000187296
WBInteraction000187471
WBInteraction000194277
WBInteraction000196623
WBInteraction000209245
WBInteraction000211602
WBInteraction000225064
WBInteraction000228850
WBInteraction000228857
WBInteraction000229898
WBInteraction000234895
WBInteraction000235030
WBInteraction000238722
WBInteraction000240369
WBInteraction000244112
WBInteraction000244824
WBInteraction000246642
WBInteraction000248394
WBInteraction000252755
WBInteraction000258335
WBInteraction000263560
WBInteraction000266001
WBInteraction000272279
WBInteraction000274515
WBInteraction000277452
WBInteraction000280920
WBInteraction000290957
WBInteraction000293190
WBInteraction000299081
WBInteraction000309345
WBInteraction000312551
WBInteraction000317110
WBInteraction000317193
WBInteraction000318566
WBInteraction000322615
WBInteraction000323485
WBInteraction000324816
WBInteraction000328049
WBInteraction000332689
WBInteraction000340292
WBInteraction000341859
WBInteraction000351294
WBInteraction000351535
WBInteraction000352350
WBInteraction000359736
WBInteraction000360016
WBInteraction000360887
WBInteraction000363933
WBInteraction000364688
WBInteraction000366392
WBInteraction000367555
WBInteraction000371278
WBInteraction000371357
WBInteraction000373308
WBInteraction000382015
WBInteraction000384391
WBInteraction000388005
WBInteraction000391145
WBInteraction000396311
WBInteraction000397702
WBInteraction000398634
WBInteraction000400790
WBInteraction000402178
WBInteraction000404409
WBInteraction000404776
WBInteraction000406180
WBInteraction000407125
WBInteraction000407145
WBInteraction000408945
WBInteraction000413573
WBInteraction000414310
WBInteraction000426024
WBInteraction000426091
WBInteraction000426994
WBInteraction000427636
WBInteraction000430073
WBInteraction000431026
WBInteraction000432221
WBInteraction000432812
WBInteraction000438024
WBInteraction000439689
WBInteraction000442174
WBInteraction000444157
WBInteraction000446524
WBInteraction000453860
WBInteraction000454866
WBInteraction000455176
WBInteraction000457332
WBInteraction000459678
WBInteraction000462627
WBInteraction000462867
WBInteraction000514567
WBInteraction000514568
WBInteraction000514569
WBInteraction000540650
WBInteraction000541009
WBInteraction000546860
WBProcessWBbiopr:00000121
Map_infoMapIIIPosition-2.57882Error0.009833
PositivePositive_cloneB0393Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5500
4625
Pseudo_map_position
ReferenceWBPaper00026147
WBPaper00026699
WBPaper00030935
WBPaper00038491
WBPaper00043173
WBPaper00044609
WBPaper00047687
WBPaper00051758
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene