WormBase Tree Display for Gene: WBGene00006376
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WBGene00006376 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C24G6 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | syp-2 | Person_evidence | WBPerson1547 | |||||
Sequence_name | C24G6.1 | ||||||||
Molecular_name | C24G6.1 | ||||||||
C24G6.1.1 | |||||||||
CE17456 | |||||||||
Other_name | CELE_C24G6.1 | Accession_evidence | NDB | BX284605 | |||||
Public_name | syp-2 | ||||||||
DB_info | Database | AceView | gene | 5G17 | |||||
WormQTL | gene | WBGene00006376 | |||||||
WormFlux | gene | WBGene00006376 | |||||||
NDB | locus_tag | CELE_C24G6.1 | |||||||
NCBI | gene | 178938 | |||||||
RefSeq | protein | NM_072061.7 | |||||||
TREEFAM | TREEFAM_ID | TF333776 | |||||||
TrEMBL | UniProtAcc | O76388 | |||||||
UniProt_GCRP | UniProtAcc | O76388 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | syp | ||||||||
Allele (21) | |||||||||
Strain | WBStrain00000287 | ||||||||
WBStrain00034784 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (8) | |||||||||
Ortholog (18) | |||||||||
Structured_description | Concise_description | syp-2 encodes a coiled-coil protein; during meiosis, syp-2 activity is required for the normal progression of chromosome organization in the nucleus, for maintaining stable pairing between homologous chromosomes subsequent to initial pairing, and for productive crossover events and chiasmata formation; SYP-2 localizes to the region between paired homologous chromosomes during pachytene and disappears from this interface by late diakinesis, suggesting that SYP-2 is a structural component of the central element of the synaptonemal complex (SC); SYP-2 localization to the SC is dependent upon activity of HIM-3 and REC-8, meiosis-specific axis components, while SYP-1, an additional SC component, and SYP-2 are interdependent for localization to the SC. | Paper_evidence | WBPaper00005486 | |||||
WBPaper00006086 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 19 Mar 2009 00:00:00 | ||||||||
Automated_description | Involved in positive regulation of reciprocal meiotic recombination and synaptonemal complex assembly. Located in central element. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C24G6.1 | |||||||
Corresponding_transcript | C24G6.1.1 | ||||||||
Other_sequence | FD517546.1 | ||||||||
CSC02241_1 | |||||||||
Associated_feature | WBsf646810 | ||||||||
WBsf646811 | |||||||||
WBsf661265 | |||||||||
WBsf231769 | |||||||||
Experimental_info | RNAi_result (15) | ||||||||
Expr_pattern | Expr2680 | ||||||||
Expr1022707 | |||||||||
Expr1032574 | |||||||||
Expr1145134 | |||||||||
Expr1200231 | |||||||||
Expr2017185 | |||||||||
Expr2035321 | |||||||||
Drives_construct | WBCnstr00006076 | ||||||||
WBCnstr00034383 | |||||||||
Construct_product | WBCnstr00006065 | ||||||||
WBCnstr00006076 | |||||||||
WBCnstr00016719 | |||||||||
WBCnstr00034383 | |||||||||
Antibody | WBAntibody00000673 | ||||||||
WBAntibody00002302 | |||||||||
WBAntibody00002754 | |||||||||
WBAntibody00002943 | |||||||||
Microarray_results (18) | |||||||||
Expression_cluster (150) | |||||||||
Interaction (354) | |||||||||
Map_info | Map | V | Position | -1.67459 | Error | 0.0238 | |||
Positive | Positive_clone | C24G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4717 | |||||||
4944 | |||||||||
Pseudo_map_position | |||||||||
Reference (54) | |||||||||
Remark (2) | |||||||||
Method | Gene |