WormBase Tree Display for Gene: WBGene00004701
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WBGene00004701 | SMap | S_parent | Sequence | EEED8 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | rsp-4 | Person_evidence | WBPerson297 | |||||
Sequence_name | EEED8.7 | ||||||||
Molecular_name | EEED8.7a | ||||||||
EEED8.7a.1 | |||||||||
CE01891 | |||||||||
EEED8.7b | |||||||||
CE27910 | |||||||||
EEED8.7b.1 | |||||||||
EEED8.7b.2 | |||||||||
Other_name | srp-2 | ||||||||
CeSC35 | |||||||||
CELE_EEED8.7 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | rsp-4 | ||||||||
DB_info | Database | AceView | gene | 2F678 | |||||
WormQTL | gene | WBGene00004701 | |||||||
WormFlux | gene | WBGene00004701 | |||||||
NDB | locus_tag | CELE_EEED8.7 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00004701|UniProtKB=Q09511 | |||||||
family | PTHR23147 | ||||||||
NCBI | gene | 173915 | |||||||
RefSeq | protein | NM_001393068.1 | |||||||
NM_062613.4 | |||||||||
SwissProt | UniProtAcc | Q09511 | |||||||
TREEFAM | TREEFAM_ID | TF106262 | |||||||
UniProt_GCRP | UniProtAcc | Q09511 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rsp | ||||||||
Allele (22) | |||||||||
Strain | WBStrain00047545 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (16) | |||||||||
Contained_in_operon | CEOP2743 | ||||||||
Ortholog (36) | |||||||||
Paralog | WBGene00004315 | Caenorhabditis elegans | From_analysis | Panther | |||||
WBGene00004703 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00013293 | Caenorhabditis elegans | From_analysis | Panther | ||||||
Structured_description | Concise_description | rsp-4 encodes, along with rsp-5, one of two C. elegans orthologs of the vertebrate SC35 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation. | Paper_evidence | WBPaper00003988 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 20 Mar 2012 00:00:00 | ||||||||
Automated_description | Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and lung cancer (multiple). Is an ortholog of human SRSF2 (serine and arginine rich splicing factor 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||
DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:6000 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:0050908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:5410 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:3907 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
DOID:9119 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10783) | ||||||
Molecular_info (4) | |||||||||
Experimental_info | RNAi_result (30) | ||||||||
Expr_pattern | Expr1140 | ||||||||
Expr1022567 | |||||||||
Expr1032321 | |||||||||
Expr1147687 | |||||||||
Expr2015561 | |||||||||
Expr2033796 | |||||||||
Drives_construct | WBCnstr00010102 | ||||||||
WBCnstr00035432 | |||||||||
Construct_product | WBCnstr00035432 | ||||||||
Microarray_results (30) | |||||||||
Expression_cluster (132) | |||||||||
Interaction (117) | |||||||||
Map_info | Map | II | Position | -1.7847 | Error | 0.000271 | |||
Positive | Positive_clone | EEED8 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4588 | |||||||
Pseudo_map_position | |||||||||
Reference (14) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |