WormBase Tree Display for Gene: WBGene00004052
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WBGene00004052 | SMap | S_parent | Sequence | H23L24 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | parg-2 | Person_evidence | WBPerson236 | |||
Sequence_name | H23L24.5 | ||||||
Molecular_name | H23L24.5 | ||||||
H23L24.5.1 | |||||||
CE32685 | |||||||
Other_name | pme-4 | ||||||
CELE_H23L24.5 | Accession_evidence | NDB | BX284604 | ||||
Public_name | parg-2 | ||||||
DB_info | Database (12) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | parg | ||||||
Allele (43) | |||||||
Strain | WBStrain00035943 | ||||||
WBStrain00047360 | |||||||
WBStrain00047361 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (22) | |||||||
Ortholog (41) | |||||||
Paralog | WBGene00004051 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | parg-2 (formerly known as pme-4) encodes a poly(ADP-ribose) glycohydrolase (PARG) orthologous to human PARG (OMIM:603501) and paralogous to PARG-1; PARG-2 exhibits poly(ADP-ribose) glycohydrolase activity in vitro, and is required in vivo for normal resistance to ionizing radiation; PARG-2 is primarily expressed in the cytoplasm of nerve cells in the head and tail, and also in embryos; neuronal expression of PARG-2 may reflect a requirement for PARG in preventing neurodegeneration like that seen in Drosophila. | Paper_evidence | WBPaper00005600 | |||
WBPaper00028953 | |||||||
WBPaper00029104 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 14 Nov 2014 00:00:00 | ||||||
Automated_description | Enables poly(ADP-ribose) glycohydrolase activity. Involved in nucleotide-sugar metabolic process and response to gamma radiation. Located in cytoplasm. Expressed in head neurons and tail neurons. Is an ortholog of human BPHL (biphenyl hydrolase like) and PARG (poly(ADP-ribose) glycohydrolase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info (4) | |||||||
Experimental_info | RNAi_result | WBRNAi00013332 | Inferred_automatically | RNAi_primary | |||
WBRNAi00033743 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00016298 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00065517 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00049464 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00065516 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00102083 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr4510 | ||||||
Expr1016211 | |||||||
Expr1153191 | |||||||
Expr2014733 | |||||||
Expr2032967 | |||||||
Drives_construct | WBCnstr00004939 | ||||||
WBCnstr00037944 | |||||||
Construct_product | WBCnstr00037944 | ||||||
Microarray_results (17) | |||||||
Expression_cluster (263) | |||||||
Interaction | WBInteraction000253282 | ||||||
WBInteraction000580252 | |||||||
Map_info | Map | IV | Position | 3.95647 | Error | 0.001836 | |
Positive | Positive_clone | H23L24 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4592 | |||||
4940 | |||||||
Pseudo_map_position | |||||||
Reference (11) | |||||||
Remark | Sequence connection via email from [Desnoyers S], [krb 020729] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |