WormBase Tree Display for Gene: WBGene00003406
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| WBGene00003406 | SMap | S_parent | Sequence | Y37D8A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mrg-1 | |||||||
| Sequence_name | Y37D8A.9 | ||||||||
| Molecular_name | Y37D8A.9a | ||||||||
| Y37D8A.9a.1 | |||||||||
| CE20213 | |||||||||
| Y37D8A.9b | |||||||||
| CE41465 | |||||||||
| Y37D8A.9b.1 | |||||||||
| Other_name | CELE_Y37D8A.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | mrg-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00003406 | |||||
| WormFlux | gene | WBGene00003406 | |||||||
| NDB | locus_tag | CELE_Y37D8A.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003406|UniProtKB=A7DTF0 | |||||||
| family | PTHR10880 | ||||||||
| NCBI | gene | 176702 | |||||||
| RefSeq | protein | NM_067274.6 | |||||||
| NM_001129255.6 | |||||||||
| SwissProt | UniProtAcc | A7DTF0 | |||||||
| TREEFAM | TREEFAM_ID | TF317891 | |||||||
| UniProt_GCRP | UniProtAcc | A7DTF0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mrg | ||||||||
| Allele (66) | |||||||||
| Strain | WBStrain00036098 | ||||||||
| WBStrain00040627 | |||||||||
| WBStrain00040628 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Ortholog (46) | |||||||||
| Paralog | WBGene00012551 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mrg-1 encodes a chromodomain-containing protein orthologous to mammalian MRG15, an essential mortality factor-related protein that promotes cell proliferation;during development, maternal MRG-1 is required for embryonic viability and for proliferation and survival of primordial germs cells (PGCs); in embryonic and PGC development MRG-1 likely functions as a transcriptional regulator, as loss of mrg-1 activity results in aberrant patterns of gene expression in wild-type and mutant backgrounds in germline and somatic tissues, respectively; MRG-1 is a nuclear protein that localizes to autosomes in a MES-2- and MES-4-independent manner; MRG-1 is present at all stages of development, with expression in embryos and young larvae seen in both germ and somatic cells and expression in older larvae and adults seen primarily in germ cells. | Paper_evidence | WBPaper00005292 | |||||
| WBPaper00026615 | |||||||||
| WBPaper00028985 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 27 Apr 2007 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including protein localization to euchromatin; regulation of gene expression; and sexual reproduction. Located in autosome. Part of euchromatin. Expressed in several structures, including Caa; Cpa; Psub4; oocyte; and somatic cell. Is an ortholog of human MORF4L2 (mortality factor 4 like 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y37D8A.9a | |||||||
| Y37D8A.9b | |||||||||
| Corresponding_transcript | Y37D8A.9a.1 | ||||||||
| Y37D8A.9b.1 | |||||||||
| Other_sequence | CRC04795_1 | ||||||||
| CR00738 | |||||||||
| DVC00028_1 | |||||||||
| EV852252.1 | |||||||||
| CJC18363_1 | |||||||||
| CJC13778_1 | |||||||||
| Associated_feature | WBsf651556 | ||||||||
| WBsf667549 | |||||||||
| WBsf994742 | |||||||||
| WBsf1016268 | |||||||||
| WBsf227691 | |||||||||
| WBsf227692 | |||||||||
| Experimental_info | RNAi_result (66) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00021274 | ||||||||
| WBCnstr00036134 | |||||||||
| WBCnstr00042784 | |||||||||
| Construct_product | WBCnstr00036134 | ||||||||
| Regulate_expr_cluster | WBPaper00064159:MRG-1_interacting | ||||||||
| WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs | |||||||||
| WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs | |||||||||
| Antibody | WBAntibody00000522 | ||||||||
| WBAntibody00001213 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (137) | |||||||||
| Interaction (251) | |||||||||
| Map_info | Map | III | Position | 19.1041 | Error | 0.026236 | |||
| Positive | Positive_clone | Y37D8A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (48) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
