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WormBase Tree Display for Gene: WBGene00003088

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Name Class

WBGene00003088EvidencePaper_evidenceWBPaper00006260
SMapS_parentSequenceC32C4
Identity (6)
Gene_infoBiotypeSO:0001265
Gene_classlsy
Allele (11)
Strain (13)
In_clusterLSY-6
RNASeq_FPKM (74)
GO_annotation00106192
00106193
00106194
Structured_descriptionConcise_descriptionlsy-6 encodes a microRNA and was the first microRNA discovered to have a role in nervous system development in vivo; lsy-6 is involved in the pathway for functional lateralization of the chemosensory ASE neuron; lsy-6 controls the asymmetrical expression of the gcy chemoreceptors, gcy-5 and gcy-7, in ASER and ASEL; genetic epistasis experiments indicate that the transcription of lsy-6 is regulated by lsy-2, a novel C2H2 zinc finger transcription factor; reporter gene fusion studies indicate that lsy-6 is expressed in one pair of tail neurons and seven head neurons including ASEL, but not in ASER.Paper_evidenceWBPaper00006260
WBPaper00024291
WBPaper00027031
Curator_confirmedWBPerson1843
WBPerson324
Date_last_updated23 May 2006 00:00:00
Automated_descriptionEnables mRNA 3'-UTR binding activity. Involved in determination of left/right asymmetry in nervous system and miRNA-mediated post-transcriptional gene silencing. Expressed in ASEL; head neurons; and tail neurons.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_transcriptC32C4.6
C32C4.6a
C32C4.6b
Associated_featureWBsf047573
WBsf047579
WBsf979125
Experimental_info (6)
Map_infoMapVPosition2.658Error0.010694
PositivePositive_cloneC32C4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4882
Pseudo_map_position
Reference (74)
Remarklsy-6 was mistakenly connected to C32C4.5CGC_data_submission
Rfam accession number: MI0000801
lsy-6 is a microRNAPaper_evidenceWBPaper00006260
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene