Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm. Expressed in developing hermaphrodite gonad; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in central precocious puberty 2. Is an ortholog of several human genes including MKRN1 (makorin ring finger protein 1); MKRN3 (makorin ring finger protein 3); and MKRN4P (makorin ring finger protein 4, pseudogene).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.