WormBase Tree Display for Gene: WBGene00002202
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WBGene00002202 | Evidence | Paper_evidence | WBPaper00003768 | |||
---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C03C10 | |||
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | kin | |||||
Allele (37) | ||||||
Strain | WBStrain00001347 | |||||
WBStrain00035749 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (22) | ||||||
Ortholog (37) | ||||||
Paralog (93) | ||||||
Structured_description | Concise_description | kin-19 encodes a serine/threonine kinase orthologous to Casein Kinase I (CKI); in the early embryo, kin-19 is a component of both the non-canonical Wnt signaling pathway that regulates endoderm formation in the early embryo as well as the Wnt spindle orientation pathway; during larval development, kin-19 functions in a non-canonical Wnt signaling pathway to control asymmetric division and fate specification in epidermal seam cells; kin-19 also functions with, or in parallel to, the heterochronic pathway to regulate loss of self-renewal and terminal differentiation of epidermal seam cells; KIN-19 localizes to centrosomes, the cytoplasm, and the nucleus. | Paper_evidence | WBPaper00003768 | ||
WBPaper00005445 | ||||||
WBPaper00024624 | ||||||
WBPaper00037838 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 10 Jul 2012 00:00:00 | |||||
Automated_description | Predicted to enable protein serine/threonine kinase activity. Involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytoplasm; and nucleus. Expressed in several structures, including BDU; marginal cell; seam cell; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and inclusion body myositis. Is an ortholog of human CSNK1A1 (casein kinase 1 alpha 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2451) | |
DOID:3429 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2451) | |||
Molecular_info | Corresponding_CDS | C03C10.1 | ||||
Corresponding_transcript | C03C10.1.1 | |||||
C03C10.1.2 | ||||||
C03C10.1.3 | ||||||
Other_sequence (160) | ||||||
Associated_feature (13) | ||||||
Experimental_info | RNAi_result (76) | |||||
Expr_pattern | Chronogram833 | |||||
Expr5122 | ||||||
Expr5123 | ||||||
Expr9170 | ||||||
Expr11628 | ||||||
Expr1012482 | ||||||
Expr1031289 | ||||||
Expr1143609 | ||||||
Expr2012931 | ||||||
Expr2031164 | ||||||
Drives_construct | WBCnstr00002240 | |||||
WBCnstr00004267 | ||||||
WBCnstr00008751 | ||||||
WBCnstr00013766 | ||||||
WBCnstr00036390 | ||||||
Construct_product | WBCnstr00008751 | |||||
WBCnstr00013766 | ||||||
WBCnstr00036390 | ||||||
Microarray_results (33) | ||||||
Expression_cluster (126) | ||||||
Interaction (283) | ||||||
WBProcess | WBbiopr:00000073 | |||||
Map_info (4) | ||||||
Reference (26) | ||||||
Picture | WBPicture0000013084 | |||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |