WormBase Tree Display for Gene: WBGene00001694
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WBGene00001694 | Evidence | Paper_evidence | WBPaper00003717 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F41E6 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | grd | ||||||
Allele (32) | |||||||
Strain | WBStrain00002346 | ||||||
WBStrain00051273 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00028098 | ||||||
00028099 | |||||||
00028100 | |||||||
00028101 | |||||||
Ortholog (25) | |||||||
Paralog (24) | |||||||
Structured_description | Concise_description | grd-5 encodes a hedgehog-like protein, with an N-terminal signalsequence and a C-terminal Ground domain; GRD-5 is expressed in adultanterior and posterior seam cells, overlapping GRD-3 expression; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-5 is weaklyrequired for normal molting; GRD-5 is also required for normal adultalae formation, growth to full size, and locomotion; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00002823 | |||
WBPaper00003717 | |||||||
WBPaper00004651 | |||||||
WBPaper00026841 | |||||||
WBPaper00027263 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 05 Nov 2006 00:00:00 | ||||||
Automated_description | Predicted to enable signaling receptor binding activity. Involved in embryo development. Predicted to be located in extracellular region. Expressed in anterior arcade cell; pharyngeal neurons; rectal epithelium; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info (4) | |||||||
Experimental_info | RNAi_result | WBRNAi00014746 | Inferred_automatically | RNAi_primary | |||
WBRNAi00000881 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00077019 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00032092 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076973 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076994 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00046992 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram1691 | ||||||
Expr636 | |||||||
Expr4431 | |||||||
Expr1011866 | |||||||
Expr1031011 | |||||||
Expr1150857 | |||||||
Expr2012235 | |||||||
Expr2030471 | |||||||
Drives_construct | WBCnstr00003015 | ||||||
WBCnstr00011994 | |||||||
WBCnstr00012460 | |||||||
WBCnstr00036762 | |||||||
Construct_product | WBCnstr00036762 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (276) | |||||||
Interaction (28) | |||||||
WBProcess | WBbiopr:00000123 | ||||||
Map_info | Map | V | Position | 1.49477 | Error | 0.004138 | |
Positive | Positive_clone | F41E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00002823 | ||||||
WBPaper00003717 | |||||||
WBPaper00011801 | |||||||
WBPaper00026841 | |||||||
WBPaper00028754 | |||||||
WBPaper00031588 | |||||||
WBPaper00064105 | |||||||
Remark | grd-5 is paralogous to grd-10 | Paper_evidence | WBPaper00003717 | ||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |