WormBase Tree Display for Gene: WBGene00001599
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WBGene00001599 | SMap | S_parent | Sequence | C55B7 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | glh | |||||
Allele (49) | ||||||
Legacy_information | [C.elegansII] NMK. Encodes predicted protein, 80% identity with glh-1. [KB] | |||||
Strain | WBStrain00023464 | |||||
RNASeq_FPKM (74) | ||||||
GO_annotation (27) | ||||||
Ortholog (75) | ||||||
Paralog (37) | ||||||
Structured_description | Concise_description | glh-2 encodes a putative DEAD-box RNA helicase that contains six CCHC zinc fingers and is homologous to Drosophila VASA, a germ-line-specific, ATP-dependent, RNA helicase; at non-permissive temperatures, GLH-2 plays a role in germ-line development and fertility, specifically in regulating the normal extent of germ-line proliferation, oogenesis, and the production of functional sperm; GLH-2 activity may also be required for the wild-type morphology of P granules and for localization of several protein components, but not accumulation of P granule mRNA components; GLH-2 interacts in vitro with itself and with KGB-1, a JNK-like MAP kinase; GLH-2 is a constitutive P granule component and thus, with the exception of mature sperm, is expressed in germ cells at all stages of development; GLH-2 is cytoplasmic in oocytes and the early embryo, while perinuclear in all later developmental stages as well as in the distal and medial regions of the hermaphrodite gonad; GLH-2 is expressed at barely detectable levels in males. | Paper_evidence | WBPaper00002611 | ||
WBPaper00004229 | ||||||
WBPaper00004672 | ||||||
WBPaper00005583 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 26 Aug 2004 00:00:00 | |||||
Automated_description | Enables JUN kinase binding activity; RNA helicase activity; and protein self-association. Involved in germ cell development and post-embryonic development. Located in P granule. Expressed in germ line and gonad. Is an ortholog of human DDX4 (DEAD-box helicase 4). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | C55B7.1 | ||||
Corresponding_transcript | C55B7.1.1 | |||||
Other_sequence | XI05257 | |||||
CRC03891_1 | ||||||
CR11481 | ||||||
CR02743 | ||||||
CRC02632_1 | ||||||
CBC00448_1 | ||||||
CRC08782_1 | ||||||
XIC04382_1 | ||||||
Associated_feature | WBsf643376 | |||||
WBsf217843 | ||||||
WBsf217844 | ||||||
WBsf217845 | ||||||
Experimental_info | RNAi_result | WBRNAi00065813 | Inferred_automatically | RNAi_primary | ||
WBRNAi00075504 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00065814 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00065811 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00043223 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00114753 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00085041 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00003236 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr1605 | |||||
Expr1606 | ||||||
Expr1024143 | ||||||
Expr1030960 | ||||||
Expr1147203 | ||||||
Expr2012093 | ||||||
Expr2030329 | ||||||
Drives_construct | WBCnstr00019491 | |||||
WBCnstr00036834 | ||||||
WBCnstr00042696 | ||||||
Construct_product | WBCnstr00036834 | |||||
Antibody | WBAntibody00000137 | |||||
WBAntibody00001620 | ||||||
Microarray_results (21) | ||||||
Expression_cluster (183) | ||||||
Interaction (30) | ||||||
Map_info (3) | ||||||
Reference (48) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |