WormBase Tree Display for Gene: WBGene00001502
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WBGene00001502 | SMap | S_parent | Sequence | F52D10 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | ftt | |||||
Allele (31) | ||||||
Legacy_information | [Iino Y] predicted gene product has sequence similarity to the 14-3-3 family of proteins. | |||||
Strain | WBStrain00027454 | |||||
WBStrain00055539 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (17) | ||||||
Ortholog (52) | ||||||
Paralog | WBGene00003920 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||
Panther | ||||||
WormBase-Compara | ||||||
WBGene00010919 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | ftt-2 encodes a 14-3-3 protein; FTT-2 is required for regulating the localization of the product of YAP-1, a Yes-associated protein (Yap) homolog, between the cytoplasm and the nucleus. | Paper_evidence | WBPaper00041976 | ||
WBPaper00002793 | ||||||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 12 Mar 2013 00:00:00 | |||||
Automated_description | Enables DNA-binding transcription factor binding activity. Involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus. Located in cytoplasm and nucleus. Expressed in several structures, including C; E; Psub3; gonad; and intestine. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:8719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |||
DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |||
DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12855) | |||
DOID:2101 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |||
DOID:2394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | |||
Molecular_info | Corresponding_CDS | F52D10.3a | ||||
F52D10.3c | ||||||
Corresponding_CDS_history | F52D10.3b:wp121 | |||||
F52D10.3b:wp271 | ||||||
Corresponding_transcript | F52D10.3a.1 | |||||
F52D10.3c.1 | ||||||
Other_sequence (379) | ||||||
Associated_feature (22) | ||||||
Experimental_info | RNAi_result (65) | |||||
Expr_pattern | Expr677 | |||||
Expr678 | ||||||
Expr3992 | ||||||
Expr4515 | ||||||
Expr14505 | ||||||
Expr1014656 | ||||||
Expr1030902 | ||||||
Expr1151782 | ||||||
Expr2011916 | ||||||
Expr2030153 | ||||||
Drives_construct | WBCnstr00009103 | |||||
WBCnstr00012073 | ||||||
WBCnstr00036906 | ||||||
Construct_product | WBCnstr00009103 | |||||
WBCnstr00012073 | ||||||
WBCnstr00036906 | ||||||
Antibody | WBAntibody00001182 | |||||
Microarray_results (31) | ||||||
Expression_cluster (201) | ||||||
Interaction (399) | ||||||
WBProcess | WBbiopr:00000025 | |||||
Map_info (4) | ||||||
Reference (37) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |