WormBase Tree Display for Gene: WBGene00001502
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WBGene00001502 | SMap | S_parent | Sequence | F52D10 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ftt | ||||||
Allele (31) | |||||||
Legacy_information | [Iino Y] predicted gene product has sequence similarity to the 14-3-3 family of proteins. | ||||||
Strain | WBStrain00027454 | ||||||
WBStrain00055539 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (17) | |||||||
Ortholog (52) | |||||||
Paralog | WBGene00003920 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00010919 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | ftt-2 encodes a 14-3-3 protein; FTT-2 is required for regulating the localization of the product of YAP-1, a Yes-associated protein (Yap) homolog, between the cytoplasm and the nucleus. | Paper_evidence | WBPaper00041976 | |||
WBPaper00002793 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 12 Mar 2013 00:00:00 | ||||||
Automated_description | Enables DNA-binding transcription factor binding activity. Involved in cytoplasmic sequestering of protein; dauer larval development; and negative regulation of protein import into nucleus. Located in cytoplasm and nucleus. Expressed in several structures, including C; E; Psub3; gonad; and intestine. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ovarian cancer; and urinary bladder cancer. Is an ortholog of human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) and YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:8719 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12855) | ||||
DOID:2101 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
DOID:2394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10773) | ||||
Molecular_info | Corresponding_CDS (2) | ||||||
Corresponding_CDS_history | F52D10.3b:wp121 | ||||||
F52D10.3b:wp271 | |||||||
Corresponding_transcript | F52D10.3a.1 | ||||||
F52D10.3c.1 | |||||||
Other_sequence (379) | |||||||
Associated_feature (22) | |||||||
Experimental_info | RNAi_result (65) | ||||||
Expr_pattern | Expr677 | ||||||
Expr678 | |||||||
Expr3992 | |||||||
Expr4515 | |||||||
Expr14505 | |||||||
Expr1014656 | |||||||
Expr1030902 | |||||||
Expr1151782 | |||||||
Expr2011916 | |||||||
Expr2030153 | |||||||
Drives_construct | WBCnstr00009103 | ||||||
WBCnstr00012073 | |||||||
WBCnstr00036906 | |||||||
Construct_product | WBCnstr00009103 | ||||||
WBCnstr00012073 | |||||||
WBCnstr00036906 | |||||||
Antibody | WBAntibody00001182 | ||||||
Microarray_results (31) | |||||||
Expression_cluster (201) | |||||||
Interaction (399) | |||||||
WBProcess | WBbiopr:00000025 | ||||||
Map_info | Map | X | Position | 4.88794 | Error | 0.044755 | |
Positive | Positive_clone | F52D10 | Person_evidence | WBPerson284 | |||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
Mapping_data | Multi_point | 5040 | |||||
Pseudo_map_position | |||||||
Reference (37) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |