WormBase Tree Display for Gene: RGD:1589755

RGD:1589755 Identity: Name: CGC_name: Tyr Inferred_automatically: AGR_import
      Public_name: Tyr
    DB_info: Database: RGD id 1589755
        AGR cURI RGD:1589755
        EnsEMBL ENSEMBL_geneID ENSRNOG00000016421
        UniProt UniProt_AC D4A9G4
            A6I5Y6
            A6I5Y7
    Species: Rattus norvegicus
    Status: Live
  Gene_info: Biotype: SO:0001217
    Ortholog: WBGene00015332 Caenorhabditis elegans From_analysis: OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      WBGene00010661 Caenorhabditis elegans From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      WBGene00021553 Caenorhabditis elegans From_analysis: OrthoFinder
            OrthoInspector
            Panther
    Structured_description: Automated_description: Predicted to enable copper ion binding activity; protein homodimerization activity; and tyrosinase activity. Involved in several processes, including response to UV; response to cAMP; and response to vitamin D. Predicted to be located in melanosome and perinuclear region of cytoplasm. Used to study oculocutaneous albinism. Human ortholog(s) of this gene implicated in several diseases, including melanoma (multiple); ocular albinism 1; oculocutaneous albinism (multiple); retinoschisis; and vitiligo. Orthologous to human TYR (tyrosinase); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; INTERACTS WITH 6-propyl-2-thiouracil; actinomycin D; atrazine. Inferred_automatically: AGR_import