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WormBase Tree Display for Gene: HGNC:42

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Name Class

HGNC:42IdentityNameCGC_nameAbcb11Inferred_automaticallyAGR_import
Other_name (14)
Public_nameAbcb11
DB_infoDatabaseHGNCid42
AGRcURIHGNC:42
EnsEMBLENSEMBL_geneIDENSG00000073734
ENSG00000276582
UniProtUniProt_ACO95342
OMIMgene603201
DOidDOID:0070232
DOID:0070222
DOID:5082
DOID:1852
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00003996Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
PhylomeDB
WBGene00003995Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
SonicParanoid
WBGene00004003Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OMA
OrthoFinder
OrthoInspector
PhylomeDB
SonicParanoid
WBGene00004002Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004000Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00003997Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00003998Caenorhabditis elegansFrom_analysisOMA
OrthoFinder
PhylomeDB
WBGene00004006Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
WBGene00004001Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OrthoFinder
PhylomeDB
Structured_descriptionAutomated_descriptionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import