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WormBase Tree Display for Gene: HGNC:2623

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Name Class

HGNC:2623IdentityNameCGC_nameCYP2C9Inferred_automaticallyAGR_import
Other_name (18)
Public_nameCYP2C9
DB_infoDatabaseHGNCid2623
AGRcURIHGNC:2623
EnsEMBLENSEMBL_geneIDENSG00000138109
UniProtUniProt_ACP11712
OMIMgene601130
DOidDOID:9351
DOID:4195
DOID:9993
DOID:11054
DOID:0080665
DOID:9352
DOID:10763
DOID:5520
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00018413Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
Panther
PhylomeDB
SonicParanoid
WBGene00019472Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00015043Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00015044Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00015045Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00015400Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00016786Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
OMA
Panther
WBGene00010589Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
Panther
PhylomeDB
SonicParanoid
WBGene00021168Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
Panther
SonicParanoid
WBGene00012448Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import