WormBase Tree Display for Gene: HGNC:2480
expand all nodes | collapse all nodes | view schema
| HGNC:2480 | Identity | Name | CGC_name | Cst8 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:736077 | |||||
| CRES | ||||||
| CTES5 | ||||||
| cystatin 8 (cystatin-related epididymal specific) | ||||||
| cystatin-8 | ||||||
| cystatin-related epididymal spermatogenic protein | ||||||
| cystatin-related epididymal-specific | ||||||
| Public_name | Cst8 | |||||
| DB_info | Database | HGNC | id | 2480 | ||
| AGR | cURI | HGNC:2480 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000125815 | ||||
| UniProt | UniProt_AC | O60676 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00000535 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| Hieranoid | ||||||
| OrthoFinder | ||||||
| WBGene00000534 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | |||
| Hieranoid | ||||||
| OrthoFinder | ||||||
| Structured_description | Automated_description | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] | Inferred_automatically | AGR_import |
