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WormBase Tree Display for Gene: HGNC:10787

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Name Class

HGNC:10787IdentityNameCGC_nameSrsf5Inferred_automaticallyAGR_import
Other_nameRGD:734021
Hrs
SFRS5
SR splicing factor 5
SRP40
delayed-early protein HRS
pre-mRNA-splicing factor SRP40
serine/arginine-rich splicing factor 5
splicing factor, arginine/serine-rich 5
Public_nameSrsf5
DB_infoDatabaseHGNCid10787
AGRcURIHGNC:10787
EnsEMBLENSEMBL_geneIDENSG00000100650
UniProtUniProt_ACQ13243
DOidDOID:4467
DOID:234
DOID:1612
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00004699Caenorhabditis elegansFrom_analysisOMA
OrthoInspector
Panther
WBGene00004698Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoInspector
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThe protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]Inferred_automaticallyAGR_import