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WormBase Tree Display for Gene: WBGene00006381

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Name Class

WBGene00006381SMapS_parentSequenceY54E2A
IdentityVersion1
NameCGC_nametac-1Person_evidenceWBPerson208
Sequence_nameY54E2A.3
Molecular_nameY54E2A.3
Y54E2A.3.1
CE20302
Other_name2P40Accession_evidenceEMBLAF326937
CELE_Y54E2A.3Accession_evidenceNDBBX284602
Public_nametac-1
DB_infoDatabaseAceViewgene2P38
WormQTLgeneWBGene00006381
WormFluxgeneWBGene00006381
NDBlocus_tagCELE_Y54E2A.3
NCBIgene175133
RefSeqproteinNM_064658.8
SwissProtUniProtAccG5ECG0
UniProt_GCRPUniProtAccG5ECG0
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtac
Allele (20)
StrainWBStrain00037424
WBStrain00007335
WBStrain00007333
WBStrain00050672
RNASeq_FPKM (74)
GO_annotation (46)
Contained_in_operonCEOP2648
Ortholog (20)
Structured_descriptionConcise_descriptiontac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm.Paper_evidenceWBPaper00006059
WBPaper00006060
WBPaper00006061
Curator_confirmedWBPerson1843
Date_last_updated17 Mar 2006 00:00:00
Automated_descriptionEnables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY54E2A.3
Corresponding_transcriptY54E2A.3.1
Other_sequenceAF326937
FG620567.1
Associated_featureWBsf650765
WBsf224306
Experimental_infoRNAi_result (18)
Expr_patternExpr2681
Expr2683
Expr2684
Expr2685
Expr12439
Expr1020108
Expr1032578
Expr1160809
Expr2017202
Expr2035338
Construct_productWBCnstr00005024
WBCnstr00010900
WBCnstr00015616
WBCnstr00015617
WBCnstr00020876
WBCnstr00021102
WBCnstr00022253
WBCnstr00022255
WBCnstr00022258
WBCnstr00040176
AntibodyWBAntibody00000668
WBAntibody00000669
WBAntibody00000670
WBAntibody00002182
WBAntibody00002963
WBAntibody00003043
Microarray_results (18)
Expression_cluster (114)
Interaction (152)
Map_infoMapIIPosition23.4578Error0.010609
PositivePositive_cloneY54E2AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00006059
WBPaper00006060
WBPaper00006061
WBPaper00006342
WBPaper00006532
WBPaper00011503
WBPaper00019326
WBPaper00024771
WBPaper00026170
WBPaper00026660
WBPaper00027235
WBPaper00028423
WBPaper00029263
WBPaper00030890
WBPaper00034952
WBPaper00035895
WBPaper00036179
WBPaper00036900
WBPaper00036926
WBPaper00037300
WBPaper00041735
WBPaper00045213
WBPaper00045565
WBPaper00047459
WBPaper00048516
WBPaper00052015
WBPaper00062697
WBPaper00063024
WBPaper00063688
WBPaper00064278
WBPaper00064679
WBPaper00064722
WBPaper00064887
WBPaper00064947
WBPaper00065650
Remark (2)
MethodGene