WormBase Tree Display for Gene: WBGene00003917

WBGene00003917 SMap: S_parent: Sequence: F58B6
  Identity: Version: 2
    Name: CGC_name: par-2 Person_evidence: WBPerson314
      Sequence_name: F58B6.3
      Molecular_name (19)
      Other_name: CELE_F58B6.3 Accession_evidence: NDB BX284603
      Public_name: par-2
    DB_info: Database: AceView gene 3C183
        WormQTL gene WBGene00003917
        WormFlux gene WBGene00003917
        NDB locus_tag CELE_F58B6.3
        Panther gene CAEEL|WormBase=WBGene00003917|UniProtKB=Q965F9
          family PTHR44080
        NCBI gene 175275
        RefSeq protein NM_001420607.1
            NM_001027459.7
            NM_001420609.1
            NM_001420606.1
            NM_001381725.1
        TrEMBL UniProtAcc A0A8S4SQT8
            A0A8S4SL65
            A0A8S4SK97
            H1ZUX3
            Q965F9
        UniProt_GCRP UniProtAcc A0A8S4SQT8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 02 Jan 2022 21:17:43 WBPerson1983 Event: Split_into: WBGene00306125
      Split_into: WBGene00306125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: par
    Allele (329)
    Legacy_information: it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless).
      See also e2030
      [C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK]
    Strain (17)
    RNASeq_FPKM (74)
    GO_annotation (26)
    Contained_in_operon: CEOP3056
    Ortholog (22)
    Structured_description: Concise_description: par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. Paper_evidence: WBPaper00005115
            WBPaper00005317
            WBPaper00005405
            WBPaper00005575
            WBPaper00005735
            WBPaper00005778
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F58B6.3a
      F58B6.3b
      F58B6.3c
      F58B6.3d
      F58B6.3e
    Corresponding_CDS_history: F58B6.3:wp19
      F58B6.3a:wp229
      F58B6.3a:wp283
      F58B6.3b:wp150
    Corresponding_transcript: F58B6.3a.1
      F58B6.3b.1
      F58B6.3c.1
      F58B6.3d.1
      F58B6.3e.1
      F58B6.3e.2
      F58B6.3e.3
      F58B6.3e.4
      F58B6.3e.5
    Other_sequence: CR05646
      CRC02017_1
      MPC00003_1
    Associated_feature (14)
  Experimental_info (9)
  Map_info: Map: III Position: -23.7021 Error: 0.225136
    Well_ordered
    Positive: Positive_clone: F58B6 Inferred_automatically: From sequence, transcript, pseudogene data
        Y11F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 2720
        2721
        4699
      Multi_point (11)
    Landmark_gene
  Reference: WBPaper00001032
    WBPaper00001152
    WBPaper00001240
    WBPaper00001361
    WBPaper00001477
    WBPaper00001516
    WBPaper00001581
    WBPaper00001628
    WBPaper00001639
    WBPaper00001654
    WBPaper00001725
    WBPaper00001791
    WBPaper00001901
    WBPaper00001974
    WBPaper00002111
    WBPaper00002346
    WBPaper00002376
    WBPaper00002400
    WBPaper00002495
    WBPaper00002506
    WBPaper00002531
    WBPaper00002581
    WBPaper00002583
    WBPaper00002654
    WBPaper00002700
    WBPaper00002922
    WBPaper00003061
    WBPaper00003065
    WBPaper00003175
    WBPaper00003198
    WBPaper00003228
    WBPaper00003284
    WBPaper00003385
    WBPaper00003624
    WBPaper00003651
    WBPaper00003753
    WBPaper00003758
    WBPaper00003944
    WBPaper00004112
    WBPaper00004115
    WBPaper00004134
    WBPaper00004151
    WBPaper00004183
    WBPaper00004200
    WBPaper00004230
    WBPaper00004323
    WBPaper00004333
    WBPaper00004400
    WBPaper00004403
    WBPaper00004455
    WBPaper00004509
    WBPaper00004513
    WBPaper00004519
    WBPaper00004549
    WBPaper00004654
    WBPaper00004846
    WBPaper00004995
    WBPaper00005046
    WBPaper00005079
    WBPaper00005095
    WBPaper00005193
    WBPaper00005199
    WBPaper00005297
    WBPaper00005317
    WBPaper00005383
    WBPaper00005405
    WBPaper00005493
    WBPaper00005515
    WBPaper00005575
    WBPaper00005683
    WBPaper00005827
    WBPaper00005830
    WBPaper00005878
    WBPaper00005918
    WBPaper00005945
    WBPaper00006019
    WBPaper00006085
    WBPaper00006196
    WBPaper00006199
    WBPaper00006200
    WBPaper00006270
    WBPaper00006311
    WBPaper00006320
    WBPaper00006387
    WBPaper00006462
    WBPaper00010112
    WBPaper00010488
    WBPaper00010891
    WBPaper00010952
    WBPaper00011018
    WBPaper00011113
    WBPaper00011570
    WBPaper00011593
    WBPaper00011595
    WBPaper00012379
    WBPaper00012601
    WBPaper00013493
    WBPaper00013869
    WBPaper00013870
    WBPaper00013871
    WBPaper00013902
    WBPaper00014022
    WBPaper00014023
    WBPaper00014100
    WBPaper00014183
    WBPaper00014312
    WBPaper00014387
    WBPaper00014912
    WBPaper00014914
    WBPaper00015102
    WBPaper00015113
    WBPaper00015412
    WBPaper00015681
    WBPaper00016484
    WBPaper00016485
    WBPaper00017084
    WBPaper00017181
    WBPaper00017390
    WBPaper00017570
    WBPaper00017571
    WBPaper00017572
    WBPaper00017657
    WBPaper00017722
    WBPaper00017725
    WBPaper00017726
    WBPaper00017752
    WBPaper00017797
    WBPaper00017940
    WBPaper00017962
    WBPaper00018018
    WBPaper00018048
    WBPaper00018174
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    WBPaper00018362
    WBPaper00018365
    WBPaper00018615
    WBPaper00019358
    WBPaper00019370
    WBPaper00019665
    WBPaper00019683
    WBPaper00019687
    WBPaper00019754
    WBPaper00019759
    WBPaper00019760
    WBPaper00020804
    WBPaper00020848
    WBPaper00021802
    WBPaper00021817
    WBPaper00021828
    WBPaper00022022
    WBPaper00022051
    WBPaper00022386
    WBPaper00022626
    WBPaper00022700
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    WBPaper00022754
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    WBPaper00023166
    WBPaper00023255
    WBPaper00023493
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    WBPaper00023698
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    WBPaper00024037
    WBPaper00024321
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    WBPaper00024346
    WBPaper00024449
    WBPaper00024503
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    WBPaper00025896
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    WBPaper00027077
    WBPaper00027197
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    WBPaper00027777
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    WBPaper00028449
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    WBPaper00028862
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    WBPaper00029085
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    WBPaper00029334
    WBPaper00031005
    WBPaper00031149
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    WBPaper00031434
    WBPaper00031555
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    WBPaper00031905
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    WBPaper00032951
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    WBPaper00033501
    WBPaper00033695
    WBPaper00034570
    WBPaper00034624
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    WBPaper00034906
    WBPaper00035112
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    WBPaper00037037
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    WBPaper00037740
    WBPaper00038345
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    WBPaper00039386
    WBPaper00039463
    WBPaper00039471
    WBPaper00039750
    WBPaper00040201
    WBPaper00040275
    WBPaper00040517
    WBPaper00040657
    WBPaper00041384
    WBPaper00041402
    WBPaper00041637
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    WBPaper00042181
    WBPaper00042280
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    WBPaper00044265
    WBPaper00044359
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    WBPaper00045695
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    WBPaper00046425
    WBPaper00047321
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    WBPaper00051787
    WBPaper00052108
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    WBPaper00053666
    WBPaper00054862
    WBPaper00055138
    WBPaper00055251
    WBPaper00055603
    WBPaper00056289
    WBPaper00056801
    WBPaper00057723
    WBPaper00058014
    WBPaper00058732
    WBPaper00058751
    WBPaper00059443
    WBPaper00059536
    WBPaper00059724
    WBPaper00061080
    WBPaper00061344
    WBPaper00061640
    WBPaper00063066
    WBPaper00064191
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    WBPaper00064281
    WBPaper00064282
    WBPaper00064300
    WBPaper00064483
    WBPaper00065555
    WBPaper00065559
    WBPaper00066020
  Method: Gene