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WormBase Tree Display for Gene: WBGene00003053

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Name Class

WBGene00003053SMapS_parentSequenceC03B1
IdentityVersion1
Name (5)
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlmp
Allele (23)
StrainWBStrain00030579
WBStrain00033050
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (34)
ParalogWBGene00015471Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionlmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus; LMP-1 is widely expressed in the early embryo, with later expression seen in the intestine, coelomocytes, and neurons; LMP-1 localizes to lysosomes and is recruited to phagosomes upon lysosomal fusion.Paper_evidenceWBPaper00004254
WBPaper00006472
WBPaper00034674
WBPaper00035888
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated07 Jan 2011 00:00:00
Automated_descriptionPredicted to be involved in establishment of protein localization to organelle. Located in cytoplasmic vesicle and lysosomal membrane. Expressed in coelomocyte; germ line; and pharynx. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Is an ortholog of human LAMP2 (lysosomal associated membrane protein 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050437Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6501)
DOID:11984Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6501)
Molecular_infoCorresponding_CDSC03B1.12
Corresponding_transcriptC03B1.12.1
Other_sequence (52)
Associated_featureWBsf654062
WBsf655670
WBsf670621
WBsf1005561
WBsf1023091
WBsf237473
WBsf237474
WBsf237475
WBsf237476
Experimental_infoRNAi_resultWBRNAi00090686Inferred_automaticallyRNAi_primary
WBRNAi00008328Inferred_automaticallyRNAi_primary
WBRNAi00039488Inferred_automaticallyRNAi_primary
WBRNAi00091312Inferred_automaticallyRNAi_primary
WBRNAi00065622Inferred_automaticallyRNAi_primary
WBRNAi00027912Inferred_automaticallyRNAi_primary
Expr_pattern (12)
Drives_constructWBCnstr00001778
WBCnstr00006910
WBCnstr00012218
WBCnstr00036261
Construct_product (14)
AntibodyWBAntibody00000297
WBAntibody00002186
WBAntibody00002423
WBAntibody00002667
Microarray_results (21)
Expression_cluster (153)
Interaction (63)
WBProcessWBbiopr:00000121
Map_infoMapXPosition-2.92988Error0.003579
PositivePositive_cloneC03B1Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00004254
WBPaper00026670
WBPaper00027265
WBPaper00027349
WBPaper00030788
WBPaper00030896
WBPaper00032168
WBPaper00032283
WBPaper00033097
WBPaper00033624
WBPaper00036179
WBPaper00036617
WBPaper00036623
WBPaper00040189
WBPaper00041456
WBPaper00041563
WBPaper00047387
WBPaper00047392
WBPaper00049828
WBPaper00050406
WBPaper00052074
WBPaper00053837
WBPaper00056693
WBPaper00058174
WBPaper00059222
WBPaper00059531
WBPaper00059755
WBPaper00060994
WBPaper00061139
WBPaper00061251
WBPaper00061990
WBPaper00063147
WBPaper00064980
WBPaper00065146
WBPaper00065267
WBPaper00066025
RemarkSequence connection from [Fire AZ, Kostich M, Fambrough DM]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene