WormBase Tree Display for Gene: WBGene00001688
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| WBGene00001688 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F22B7 | ||||||
| Identity | Version | 1 | |||||||
| Name (5) | |||||||||
| DB_info | Database | AceView | gene | 3J719 | |||||
| WormQTL | gene | WBGene00001688 | |||||||
| WormFlux | gene | WBGene00001688 | |||||||
| NDB | locus_tag | CELE_F22B7.13 | |||||||
| NCBI | gene | 176210 | |||||||
| RefSeq | protein | NM_066499.5 | |||||||
| SwissProt | UniProtAcc | Q95QJ7 | |||||||
| TREEFAM | TREEFAM_ID | TF318159 | |||||||
| UniProt_GCRP | UniProtAcc | Q95QJ7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpr | ||||||||
| Allele (26) | |||||||||
| Strain | WBStrain00036782 | ||||||||
| WBStrain00007343 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Contained_in_operon | CEOP3875 | ||||||||
| Ortholog (20) | |||||||||
| Paralog | WBGene00001689 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpr-1 encodes an extremely similar (97% identity) paralog of GPR-2; GPR-1(and GPR-2) proteins have two N-terminal tetratricopeptide-like motifs anda C-terminal GoLoco/GPR (G protein regulatory) motif, the latter of whichhas also been found in mammalian AGS3 and Drosophila Pins; GPR-1 isrequired for normally asymmetrical cleavage of one-cell embryos; GPR-1 andGPR-2 form a high molecular weight (~700 kDa) complex that includes LIN-5;GPR-1 binds GDP-bound GOA-1 via a GoLoco/GPR motif, and depends on RIC-8for this binding; GPR-1/2, GOA-1, and LIN-5 colocalize at the cortex ofearly embryos; cortical enrichment of GPR-1 requires LIN-5, PAR-2, PAR-3,and LET-99; the asymmetric distribution of GPR-1/2 and LET-99 in EMS cellsis dependent on MES-1/SRC-1 signaling; GPR-1/2 is co-immunoprecipitatedwith RIC-8 and GPA-16. | Paper_evidence | WBPaper00005878 | |||||
| WBPaper00005918 | |||||||||
| WBPaper00005945 | |||||||||
| WBPaper00006289 | |||||||||
| WBPaper00024244 | |||||||||
| WBPaper00024481 | |||||||||
| WBPaper00026807 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 06 Sep 2006 00:00:00 | ||||||||
| Automated_description | Enables G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Predicted to be involved in cell division. Located in aster and cell cortex. Expressed in P lineage cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F22B7.13 | |||||||
| Corresponding_transcript | F22B7.13.1 | ||||||||
| Other_sequence | CJC06602_1 | ||||||||
| CBC04217_1 | |||||||||
| Associated_feature | WBsf225448 | ||||||||
| Experimental_info | RNAi_result (55) | ||||||||
| Expr_pattern | Expr2564 | ||||||||
| Expr10765 | |||||||||
| Expr1031007 | |||||||||
| Expr1149216 | |||||||||
| Expr2012213 | |||||||||
| Expr2030449 | |||||||||
| Drives_construct | WBCnstr00036768 | ||||||||
| Construct_product | WBCnstr00007804 | ||||||||
| WBCnstr00007805 | |||||||||
| WBCnstr00010003 | |||||||||
| WBCnstr00036768 | |||||||||
| Antibody | WBAntibody00000624 | ||||||||
| WBAntibody00000631 | |||||||||
| WBAntibody00000632 | |||||||||
| WBAntibody00000783 | |||||||||
| WBAntibody00001312 | |||||||||
| WBAntibody00001392 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (82) | |||||||||
| WBProcess | WBbiopr:00000017 | ||||||||
| Map_info | Map | III | Position | -0.210379 | Error | 0.001277 | |||
| Positive | Positive_clone | F22B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005317 | ||||||||
| WBPaper00005405 | |||||||||
| WBPaper00005878 | |||||||||
| WBPaper00005880 | |||||||||
| WBPaper00005918 | |||||||||
| WBPaper00005945 | |||||||||
| WBPaper00005985 | |||||||||
| WBPaper00006121 | |||||||||
| WBPaper00006289 | |||||||||
| WBPaper00006320 | |||||||||
| WBPaper00010166 | |||||||||
| WBPaper00010344 | |||||||||
| WBPaper00010803 | |||||||||
| WBPaper00017725 | |||||||||
| WBPaper00017879 | |||||||||
| WBPaper00019348 | |||||||||
| WBPaper00024244 | |||||||||
| WBPaper00024449 | |||||||||
| WBPaper00024543 | |||||||||
| WBPaper00024864 | |||||||||
| WBPaper00025100 | |||||||||
| WBPaper00025543 | |||||||||
| WBPaper00026807 | |||||||||
| WBPaper00027230 | |||||||||
| WBPaper00027672 | |||||||||
| WBPaper00028765 | |||||||||
| WBPaper00028955 | |||||||||
| WBPaper00029025 | |||||||||
| WBPaper00029322 | |||||||||
| WBPaper00030799 | |||||||||
| WBPaper00030892 | |||||||||
| WBPaper00031062 | |||||||||
| WBPaper00031073 | |||||||||
| WBPaper00031168 | |||||||||
| WBPaper00031354 | |||||||||
| WBPaper00031475 | |||||||||
| WBPaper00031652 | |||||||||
| WBPaper00031928 | |||||||||
| WBPaper00032096 | |||||||||
| WBPaper00032337 | |||||||||
| WBPaper00032910 | |||||||||
| WBPaper00033032 | |||||||||
| WBPaper00033077 | |||||||||
| WBPaper00035112 | |||||||||
| WBPaper00035559 | |||||||||
| WBPaper00038085 | |||||||||
| WBPaper00040003 | |||||||||
| WBPaper00040078 | |||||||||
| WBPaper00040112 | |||||||||
| WBPaper00040172 | |||||||||
| WBPaper00040657 | |||||||||
| WBPaper00041486 | |||||||||
| WBPaper00042820 | |||||||||
| WBPaper00045425 | |||||||||
| WBPaper00046208 | |||||||||
| WBPaper00047056 | |||||||||
| WBPaper00047299 | |||||||||
| WBPaper00047444 | |||||||||
| WBPaper00049936 | |||||||||
| WBPaper00050170 | |||||||||
| WBPaper00050212 | |||||||||
| WBPaper00052847 | |||||||||
| WBPaper00055155 | |||||||||
| WBPaper00055830 | |||||||||
| WBPaper00056292 | |||||||||
| WBPaper00059753 | |||||||||
| WBPaper00061021 | |||||||||
| WBPaper00061344 | |||||||||
| WBPaper00063488 | |||||||||
| Remark | Sequence connection from [Ahringer JA] | ||||||||
| Gene renamed from ags-3.2 to gpr-1 following advice from [Hodgkin J], [020808 krb] | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
