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WormBase Tree Display for Gene: WBGene00011867

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Name Class

WBGene00011867SMapS_parentSequenceT20G5
IdentityVersion3
NameCGC_namechc-1Person_evidenceWBPerson217
Sequence_nameT20G5.1
Molecular_nameT20G5.1
T20G5.1.1
CE00480
Other_nameclhc-1Paper_evidenceWBPaper00031805
CELE_T20G5.1Accession_evidenceNDBBX284603
Public_namechc-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
204 Nov 2004 16:11:20WBPerson2970Name_changeCGC_namechc-1
330 Apr 2008 14:28:36WBPerson2970Name_changeOther_nameclhc-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classchc
Allele (82)
Possibly_affected_byWBVar02153072
WBVar00000423
StrainWBStrain00037310
WBStrain00005825
RNASeq_FPKM (74)
GO_annotation (34)
Contained_in_operonCEOP3858
Ortholog (47)
Structured_descriptionConcise_descriptionchc-1 encodes the C. elegans clathrin heavy chain ortholog; loss of chc-1 activity via RNAi results in defects in receptor-mediated yolk endocytosis and thus, embryonic lethality.Paper_evidenceWBPaper00003831
Curator_confirmedWBPerson1843
Date_last_updated21 Mar 2008 00:00:00
Automated_descriptionPredicted to enable clathrin light chain binding activity. Involved in several processes, including apical protein localization; determination of adult lifespan; and positive regulation of clathrin-dependent endocytosis. Located in cell periphery; clathrin-coated endocytic vesicle; and mitotic spindle. Expressed in coelomocyte; germ line; hyp7 syncytium; hypodermal cell; and pharyngeal cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Is an ortholog of human CLTC (clathrin heavy chain) and CLTCL1 (clathrin heavy chain like 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080226Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2092)
Molecular_infoCorresponding_CDST20G5.1
Corresponding_transcriptT20G5.1.1
Other_sequence (98)
Associated_featureWBsf659485
WBsf659486
WBsf993933
WBsf993934
WBsf1015749
WBsf225683
Experimental_infoRNAi_resultWBRNAi00098763Inferred_automaticallyRNAi_primary
WBRNAi00090886Inferred_automaticallyRNAi_primary
WBRNAi00098561Inferred_automaticallyRNAi_primary
WBRNAi00078136Inferred_automaticallyRNAi_primary
WBRNAi00098522Inferred_automaticallyRNAi_primary
WBRNAi00098769Inferred_automaticallyRNAi_primary
WBRNAi00098766Inferred_automaticallyRNAi_primary
WBRNAi00092792Inferred_automaticallyRNAi_primary
WBRNAi00098563Inferred_automaticallyRNAi_primary
WBRNAi00071357Inferred_automaticallyRNAi_primary
WBRNAi00098772Inferred_automaticallyRNAi_primary
WBRNAi00082016Inferred_automaticallyRNAi_primary
WBRNAi00098776Inferred_automaticallyRNAi_primary
WBRNAi00098550Inferred_automaticallyRNAi_primary
WBRNAi00098482Inferred_automaticallyRNAi_primary
WBRNAi00098519Inferred_automaticallyRNAi_primary
WBRNAi00071863Inferred_automaticallyRNAi_primary
WBRNAi00098559Inferred_automaticallyRNAi_primary
WBRNAi00098573Inferred_automaticallyRNAi_primary
WBRNAi00098536Inferred_automaticallyRNAi_primary
WBRNAi00098540Inferred_automaticallyRNAi_primary
WBRNAi00098767Inferred_automaticallyRNAi_primary
WBRNAi00098480Inferred_automaticallyRNAi_primary
WBRNAi00082017Inferred_automaticallyRNAi_primary
WBRNAi00098765Inferred_automaticallyRNAi_primary
WBRNAi00098513Inferred_automaticallyRNAi_primary
WBRNAi00009192Inferred_automaticallyRNAi_primary
WBRNAi00087736Inferred_automaticallyRNAi_primary
WBRNAi00098538Inferred_automaticallyRNAi_primary
WBRNAi00098532Inferred_automaticallyRNAi_primary
WBRNAi00106546Inferred_automaticallyRNAi_primary
WBRNAi00082015Inferred_automaticallyRNAi_primary
WBRNAi00082018Inferred_automaticallyRNAi_primary
WBRNAi00075617Inferred_automaticallyRNAi_primary
WBRNAi00002600Inferred_automaticallyRNAi_primary
WBRNAi00098774Inferred_automaticallyRNAi_primary
WBRNAi00092773Inferred_automaticallyRNAi_primary
WBRNAi00110565Inferred_automaticallyRNAi_primary
WBRNAi00098577Inferred_automaticallyRNAi_primary
WBRNAi00077469Inferred_automaticallyRNAi_primary
WBRNAi00098544Inferred_automaticallyRNAi_primary
WBRNAi00080533Inferred_automaticallyRNAi_primary
WBRNAi00083351Inferred_automaticallyRNAi_primary
WBRNAi00098516Inferred_automaticallyRNAi_primary
WBRNAi00026333Inferred_automaticallyRNAi_primary
WBRNAi00098576Inferred_automaticallyRNAi_primary
WBRNAi00053656Inferred_automaticallyRNAi_primary
WBRNAi00085390Inferred_automaticallyRNAi_primary
WBRNAi00098761Inferred_automaticallyRNAi_primary
WBRNAi00110550Inferred_automaticallyRNAi_primary
WBRNAi00082938Inferred_automaticallyRNAi_primary
WBRNAi00114587Inferred_automaticallyRNAi_primary
WBRNAi00022632Inferred_automaticallyRNAi_primary
WBRNAi00098574Inferred_automaticallyRNAi_primary
WBRNAi00098764Inferred_automaticallyRNAi_primary
WBRNAi00103122Inferred_automaticallyRNAi_primary
WBRNAi00077455Inferred_automaticallyRNAi_primary
WBRNAi00087738Inferred_automaticallyRNAi_primary
WBRNAi00098762Inferred_automaticallyRNAi_primary
WBRNAi00098548Inferred_automaticallyRNAi_primary
WBRNAi00098510Inferred_automaticallyRNAi_primary
WBRNAi00098552Inferred_automaticallyRNAi_primary
WBRNAi00075614Inferred_automaticallyRNAi_primary
WBRNAi00098530Inferred_automaticallyRNAi_primary
WBRNAi00098575Inferred_automaticallyRNAi_primary
WBRNAi00098546Inferred_automaticallyRNAi_primary
WBRNAi00098475Inferred_automaticallyRNAi_primary
WBRNAi00098768Inferred_automaticallyRNAi_primary
Expr_pattern (13)
Drives_constructWBCnstr00000149
WBCnstr00017705
WBCnstr00030323
Construct_product (16)
Antibody (2)
Microarray_results (19)
Expression_cluster (145)
Interaction (243)
Map_infoMapIIIPosition2.01234Error0.001699
PositivePositive_cloneT20G5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (42)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene