| WBGene00001953 | SMap | S_parent | Sequence | C02B8 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | hlh-8 | Person_evidence | WBPerson346 |
| | | Sequence_name | C02B8.4 |
| | | Molecular_name | C02B8.4 |
| | | | C02B8.4.1 |
| | | | CE24777 |
| | | | C02B8.4.2 |
| | | Other_name | CELE_C02B8.4 | Accession_evidence | NDB | BX284606 |
| | | Public_name | hlh-8 |
| | DB_info | Database | AceView | gene | XI737 |
| | | | WormQTL | gene | WBGene00001953 |
| | | | WormFlux | gene | WBGene00001953 |
| | | | OMIM | disease | 101400 |
| | | | | gene | 601622 |
| | | | | | 607556 |
| | | | NDB | locus_tag | CELE_C02B8.4 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001953|UniProtKB=Q11094 |
| | | | | family | PTHR23349 |
| | | | NCBI | gene | 181069 |
| | | | RefSeq | protein | NM_076966.3 |
| | | | SwissProt | UniProtAcc | Q11094 |
| | | | UniProt_GCRP | UniProtAcc | Q11094 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | hlh |
| | Allele (88) |
| | Strain | WBStrain00027639 |
| | | WBStrain00027640 |
| | | WBStrain00030584 |
| | | WBStrain00030587 |
| | | WBStrain00030588 |
| | | WBStrain00033322 |
| | | WBStrain00037705 |
| | RNASeq_FPKM | WBls:0000002 (65) |
| | | WBls:0000003 (11) |
| | | WBls:0000004 (19) |
| | | WBls:0000006 | 0.0459607 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559705 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000006.Hermaphrodite.WBbt:0007833.SRP042619.SRX559706 |
| | | WBls:0000007 | 0.11465 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000007.Hermaphrodite.WBbt:0006770.SRP045110.SRX666568 |
| | | | 1e-10 | From_analysis (11) |
| | | WBls:0000008 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085219 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX085220 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000008.Hermaphrodite.WBbt:0007833.SRP000401.SRX145480 |
| | | WBls:0000010 (11) |
| | | WBls:0000013 | 0.827604 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099996 |
| | | | 1.27784 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099986 |
| | | | 1.4756 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022570 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099987 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099997 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX099998 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022571 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103652 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX103653 |
| | | | 5.64557 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022604 |
| | | | 8.97786 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000013.Hermaphrodite.WBbt:0007833.SRP000401.SRX1022648 |
| | | WBls:0000014 (15) |
| | | WBls:0000015 (22) |
| | | WBls:0000017 | 153.601 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343277 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343324 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0003810.SRP029448.SRX343325 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343252 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343253 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004804.SRP029448.SRX343254 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0008115.SRP029448.SRX343342 |
| | | | 25.2462 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343305 |
| | | | 39.6905 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004015.SRP029448.SRX343304 |
| | | | 567.078 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000017.Hermaphrodite.WBbt:0004458.SRP029448.SRX343278 |
| | | WBls:0000020 (16) |
| | | WBls:0000021 (15) |
| | | WBls:0000023 | 1.40009 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000023.Hermaphrodite.WBbt:0007833.SRP015688.SRX185639 |
| | | WBls:0000024 (67) |
| | | WBls:0000027 (15) |
| | | WBls:0000031 | 0.800577 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103275 |
| | | | 0.986553 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103273 |
| | | | 1.34027 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX047470 |
| | | | 1.74305 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX008139 |
| | | | 3.17222 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103274 |
| | | | 3.19433 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103277 |
| | | | 3.46702 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000031.Hermaphrodite.WBbt:0007833.SRP000401.SRX103276 |
| | | WBls:0000032 | 0.422398 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103984 |
| | | | 1.88718 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103983 |
| | | | 2.02255 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX008138 |
| | | | 2.17887 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP000401.SRX103985 |
| | | | 2.90802 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019178 |
| | | | 3.01952 | From_analysis | RNASeq.elegans.WBls:0000032.control_mean |
| | | | | | RNASeq.elegans.WBls:0000032.control_median |
| | | | 3.13101 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000032.Hermaphrodite.WBbt:0007833.SRP058023.SRX1019179 |
| | | WBls:0000035 (25) |
| | | WBls:0000038 (76) |
| | | WBls:0000041 (21) |
| | | WBls:0000052 | 0.634033 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX008140 |
| | | | 0.679811 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103271 |
| | | | 1.21292 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX037199 |
| | | | 1.38189 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103279 |
| | | | 1.95115 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103270 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103272 |
| | | | 2.26913 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103280 |
| | | | 2.322 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103278 |
| | | | 2.36531 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103269 |
| | | | 2.94581 | From_analysis | RNASeq.elegans.WBStrain00004309.WBls:0000052.Hermaphrodite.WBbt:0007833.SRP000401.SRX103281 |
| | | WBls:0000063 (102) |
| | | WBls:0000064 (14) |
| | | WBls:0000065 (16) |
| | | WBls:0000068 | 0.178011 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265362 |
| | | | 0.385751 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265364 |
| | | | 0.467023 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265363 |
| | | | 0.539177 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265365 |
| | | | 0.60268 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265361 |
| | | | 0.886753 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000068.Hermaphrodite.WBbt:0007833.SRP021083.SRX265360 |
| | | WBls:0000131 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343220 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343227 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343228 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0004015.SRP029448.SRX343229 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343225 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006771.SRP029448.SRX343226 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343221 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343222 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000131.Hermaphrodite.WBbt:0006876.SRP029448.SRX343223 |
| | | WBls:0000141 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000141.Hermaphrodite.WBbt:0007833.SRP029448.SRX343161 |
| | | WBls:0000151 | 1e-10 | From_analysis (14) |
| | | WBls:0000171 | 1e-10 | From_analysis (15) |
| | | WBls:0000181 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000181.Hermaphrodite.WBbt:0007833.SRP029448.SRX343164 |
| | | WBls:0000191 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000191.Hermaphrodite.WBbt:0007833.SRP029448.SRX343165 |
| | | WBls:0000201 | 1e-10 | From_analysis (11) |
| | | | 46.2575 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000201.Hermaphrodite.WBbt:0004015.SRP029448.SRX343287 |
| | | WBls:0000221 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343314 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0003810.SRP029448.SRX343315 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343290 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004015.SRP029448.SRX343291 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343264 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343265 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004458.SRP029448.SRX343266 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0004804.SRP029448.SRX343241 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343333 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000221.Hermaphrodite.WBbt:0008115.SRP029448.SRX343334 |
| | | WBls:0000231 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000231.Hermaphrodite.WBbt:0007833.SRP029448.SRX343167 |
| | | WBls:0000251 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0003810.SRP029448.SRX343317 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004015.SRP029448.SRX343292 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004458.SRP029448.SRX343268 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343242 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343243 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0004804.SRP029448.SRX343244 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0007833.SRP029448.SRX343168 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343335 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343336 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000251.Hermaphrodite.WBbt:0008115.SRP029448.SRX343337 |
| | | WBls:0000261 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000261.Hermaphrodite.WBbt:0007833.SRP029448.SRX343169 |
| | | WBls:0000281 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000281.Hermaphrodite.WBbt:0007833.SRP029448.SRX343170 |
| | | WBls:0000291 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343318 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0003810.SRP029448.SRX343319 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343294 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343295 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343272 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343245 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343246 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004804.SRP029448.SRX343247 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0007833.SRP029448.SRX343171 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343338 |
| | | | 2.00713 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004458.SRP029448.SRX343271 |
| | | | 5.70243 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0008115.SRP029448.SRX343339 |
| | | | 7.16502 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000291.Hermaphrodite.WBbt:0004015.SRP029448.SRX343296 |
| | | WBls:0000301 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000301.Hermaphrodite.WBbt:0007833.SRP029448.SRX343172 |
| | | WBls:0000311 | 1.7153 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000311.Hermaphrodite.WBbt:0007833.SRP029448.SRX343173 |
| | | WBls:0000321 | 1.21299 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000321.Hermaphrodite.WBbt:0007833.SRP029448.SRX343174 |
| | | WBls:0000331 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343175 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000331.Hermaphrodite.WBbt:0007833.SRP029448.SRX343176 |
| | | WBls:0000351 | 1.48626 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343178 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000351.Hermaphrodite.WBbt:0007833.SRP029448.SRX343179 |
| | | WBls:0000361 | 1.76595 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000361.Hermaphrodite.WBbt:0007833.SRP029448.SRX343180 |
| | | WBls:0000381 | 1.03641 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343297 |
| | | | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0003810.SRP029448.SRX343320 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004015.SRP029448.SRX343299 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343274 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004458.SRP029448.SRX343275 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343248 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343249 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0004804.SRP029448.SRX343250 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000381.Hermaphrodite.WBbt:0008115.SRP029448.SRX343340 |
| | | WBls:0000391 | 9.186 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000391.Hermaphrodite.WBbt:0007833.SRP029448.SRX343181 |
| | | WBls:0000401 | 18.2783 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000401.Hermaphrodite.WBbt:0007833.SRP029448.SRX343182 |
| | | WBls:0000421 | 42.662 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000421.Hermaphrodite.WBbt:0007833.SRP029448.SRX343184 |
| | | WBls:0000431 | 44.7618 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000431.Hermaphrodite.WBbt:0007833.SRP029448.SRX343185 |
| | | WBls:0000451 | 75.6363 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000451.Hermaphrodite.WBbt:0007833.SRP029448.SRX343186 |
| | | WBls:0000461 | 45.4761 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000461.Hermaphrodite.WBbt:0007833.SRP029448.SRX343187 |
| | | WBls:0000471 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343300 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343301 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004015.SRP029448.SRX343302 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004804.SRP029448.SRX343251 |
| | | | | | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0008115.SRP029448.SRX343341 |
| | | | 34.2982 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0007833.SRP029448.SRX343189 |
| | | | 83.3285 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000471.Hermaphrodite.WBbt:0004458.SRP029448.SRX343276 |
| | | WBls:0000491 | 48.4129 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000491.Hermaphrodite.WBbt:0007833.SRP029448.SRX343191 |
| | | WBls:0000501 | 94.5922 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000501.Hermaphrodite.WBbt:0007833.SRP029448.SRX343192 |
| | | WBls:0000511 | 9.93185 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000511.Hermaphrodite.WBbt:0007833.SRP029448.SRX343194 |
| | | WBls:0000521 | 32.3458 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000521.Hermaphrodite.WBbt:0007833.SRP029448.SRX343195 |
| | | WBls:0000531 | 38.2836 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343197 |
| | | | 44.4852 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000531.Hermaphrodite.WBbt:0007833.SRP029448.SRX343196 |
| | | WBls:0000541 | 37.7806 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343198 |
| | | | 8.35571 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000541.Hermaphrodite.WBbt:0007833.SRP029448.SRX343199 |
| | | WBls:0000551 | 47.2073 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000551.Hermaphrodite.WBbt:0007833.SRP029448.SRX343200 |
| | | WBls:0000561 | 10.2831 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000561.Hermaphrodite.WBbt:0007833.SRP029448.SRX343201 |
| | | WBls:0000581 | 12.3322 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000581.Hermaphrodite.WBbt:0007833.SRP029448.SRX343202 |
| | | WBls:0000621 | 1.35424 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000621.Hermaphrodite.WBbt:0007833.SRP029448.SRX343203 |
| | | WBls:0000674 | 0.409282 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265371 |
| | | | 0.441259 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265369 |
| | | | 0.564394 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265367 |
| | | | 0.594412 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265370 |
| | | | 0.793052 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265368 |
| | | | 0.999742 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000674.Hermaphrodite.WBbt:0007833.SRP021083.SRX265366 |
| | | WBls:0000676 | 0.935399 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265375 |
| | | | 1.18994 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265374 |
| | | | 1.31904 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265373 |
| | | | 1.44536 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000676.Hermaphrodite.WBbt:0007833.SRP021083.SRX265372 |
| | | WBls:0000694 | 8.46817 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000694.Hermaphrodite.WBbt:0007833.SRP029448.SRX343205 |
| | | WBls:0000695 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000695.Hermaphrodite.WBbt:0007833.SRP029448.SRX343206 |
| | | WBls:0000696 | 5.00062 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000696.Hermaphrodite.WBbt:0007833.SRP029448.SRX343207 |
| | | WBls:0000697 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000697.Hermaphrodite.WBbt:0007833.SRP029448.SRX343208 |
| | | WBls:0000699 | 11.0464 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000699.Hermaphrodite.WBbt:0007833.SRP029448.SRX343210 |
| | | WBls:0000700 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000700.Hermaphrodite.WBbt:0007833.SRP029448.SRX343211 |
| | | WBls:0000701 | 12.5856 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000701.Hermaphrodite.WBbt:0007833.SRP029448.SRX343212 |
| | | WBls:0000702 | 1e-10 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000702.Hermaphrodite.WBbt:0007833.SRP029448.SRX343213 |
| | | WBls:0000703 | 8.93255 | From_analysis | RNASeq.elegans.WBStrain00000001.WBls:0000703.Hermaphrodite.WBbt:0007833.SRP029448.SRX343214 |
| | GO_annotation (19) |
| | Ortholog (37) |
| | Paralog | WBGene00000561 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | WBGene00001954 | Caenorhabditis elegans | From_analysis | Panther |
| | | WBGene00001957 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00003595 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | WBGene00001962 | Caenorhabditis elegans | From_analysis | Panther |
| | | WBGene00001981 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00001956 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | Structured_description | Concise_description | The hlh-8 gene encodes a helix-loop-helix protein required for normal muscle development, and hence for normal defecation and egg-laying. | Paper_evidence | WBPaper00003174 |
| | | | | | WBPaper00004154 |
| | | | | | WBPaper00004482 |
| | | | | | WBPaper00005080 |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in mesodermal cell fate specification; positive regulation of transcription by RNA polymerase II; and vulval cell fate specification. Predicted to be located in nucleus. Expressed in several structures, including M.dla; M.dra; M.vla; body wall muscle cell from M lineage; and enteric muscle. Used to study Saethre-Chotzen syndrome. Human ortholog(s) of this gene implicated in several diseases, including Barber-Say syndrome; Sweeney-Cox syndrome; and synostosis (multiple). Is an ortholog of human TWIST2 (twist family bHLH transcription factor 2). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Experimental_model | DOID:14768 | Homo sapiens | Paper_evidence | WBPaper00005324 |
| | | | | | WBPaper00036744 |
| | | | | Accession_evidence | OMIM | 101400 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 03 Apr 2013 00:00:00 |
| | Potential_model | DOID:0060549 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20670) |
| | | DOID:3459 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | DOID:0080538 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | DOID:0060550 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20670) |
| | | DOID:14768 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | DOID:12960 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | DOID:2340 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | EFO:MONDO:0018363 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20670) |
| | | DOID:3770 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | | DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12428) |
| | Disease_relevance | Twist1 is a well-conserved bHLH type transcriptional regulator protein present across species including humans, involved in the development of the mesoderm; mutations in Twist1 are implicated in the craniofacial disorder Saethre-Chotzen syndrome, characterized by the premature fusion of certain skull bones (craniosynostosis), preventing the skull from growing normally and affecting the shape of the head and face; studies with the C. elegans Twist ortholog indicate that the semi-dominant mutant (n2170) shares the muscle development defective phenotypes with the loss-of-function mutant (nr2061); further, when mutations similar to Saethre-Chotzen syndrome mutations were introduced into elegans Twist, similar muscle defective phenotypes were observed, suggesting that Saethre-Chotzen syndrome may be caused, in some cases, by dominant negative proteins, rather than by haploinsufficiency of the locus. | Homo sapiens | Paper_evidence | WBPaper00005324 |
| | | | | Accession_evidence | OMIM | 101400 |
| | | | | | | 601622 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 12 May 2015 00:00:00 |
| Models_disease_in_annotation | WBDOannot00001006 |
| Models_disease_asserted | WBDOannot00000126 |
| | WBDOannot00001005 |
| Molecular_info | Corresponding_CDS | C02B8.4 |
| | Corresponding_transcript (2) |
| | Other_sequence | Oden_isotig22148 |
| | | ES413014.1 |
| | | JI213846.1 |
| | Associated_feature (14) |
| | Gene_product_binds (7249) |
| | Transcription_factor | WBTranscriptionFactor000066 |
| | | WBTranscriptionFactor000083 |
| Experimental_info | RNAi_result (14) |
| | Expr_pattern (13) |
| | Drives_construct (19) |
| | Construct_product (11) |
| | Antibody | WBAntibody00000188 |
| | | WBAntibody00001852 |
| | Microarray_results (19) |
| | Expression_cluster (88) |
| | Interaction (121) |
| | WBProcess | WBbiopr:00000040 |
| Map_info | Map | X | Position | -0.530654 | Error | 0.011006 |
| | Positive | Positive_clone | C02B8 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point | 4404 |
| | | | 4750 |
| | | | 4876 |
| | | | 5663 |
| | Pseudo_map_position |
| Reference (71) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
