WormBase Tree Display for Gene: WBGene00012005
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WBGene00012005 | SMap | S_parent | Sequence | CHROMOSOME_II | |||
---|---|---|---|---|---|---|---|
Identity | Version | 4 | |||||
Name | CGC_name | jun-1 | Person_evidence | WBPerson2962 | |||
WBPerson443 | |||||||
Sequence_name | T24H10.7 | ||||||
Molecular_name (27) | |||||||
Other_name | CELE_T24H10.7 | Accession_evidence | NDB | BX284602 | |||
Public_name | jun-1 | ||||||
DB_info | Database | AceView | gene | 2J421 | |||
WormQTL | gene | WBGene00012005 | |||||
WormFlux | gene | WBGene00012005 | |||||
NDB | locus_tag | CELE_T24H10.7 | |||||
Panther | gene | CAEEL|WormBase=WBGene00012005|UniProtKB=G5ECU7 | |||||
family | PTHR11462 | ||||||
NCBI | gene | 174452 | |||||
RefSeq | protein | NM_001356878.3 | |||||
NM_001356880.3 | |||||||
NM_001136355.4 | |||||||
NM_001356881.3 | |||||||
NM_001383910.2 | |||||||
NM_001356879.3 | |||||||
NM_001027195.4 | |||||||
NM_001027197.5 | |||||||
NM_001027196.5 | |||||||
SwissProt | UniProtAcc | G5ECU7 | |||||
TrEMBL | UniProtAcc | A0A2C9C3K0 | |||||
A0A2C9C3E7 | |||||||
A0A2C9C2T0 | |||||||
A0A2C9C2Y8 | |||||||
UniProt_GCRP | UniProtAcc | G5ECU7 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (4) | ||||||
Acquires_merge | WBGene00012001 | ||||||
WBGene00012006 | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | jun | ||||||
Allele (304) | |||||||
Strain | WBStrain00036395 | ||||||
WBStrain00036410 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (28) | |||||||
Contained_in_operon | CEOP2709 | ||||||
Ortholog (31) | |||||||
Structured_description | Concise_description | jun-1 encodes a basic-leucine zipper (bZIP) transcription factor that is the C. elegans JUN homolog; jun-1 activity is essential for regulation of ovulation, and thus normal levels of fertility; in regulating ovulation, JUN-1 functions with FOS-1 to regulate expression of plc-1 which encodes a phospholipase C essential for IP3 production and ovulation; in addition, JUN-1 interacts with FOS-1 in vitro to form heterodimers capable of binding upstream regulatory sequences of egl-13, which encodes a transcription factor required for uterine cell fate specification; jun-1 is expressed in the uterus and the spermatheca. | Paper_evidence | WBPaper00031111 | |||
WBPaper00034689 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 19 Jan 2010 00:00:00 | ||||||
Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0050861 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||
DOID:0050860 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:0050865 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205,HGNC:6206) | ||||
DOID:2957 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||||
DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:2871 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:219 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:10286 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:8567 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204,HGNC:6205) | ||||
DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:1686 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:0050744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:2870 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:1909 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:0050700 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6206) | ||||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6206) | ||||
DOID:5520 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
DOID:2526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6204) | ||||
DOID:3121 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6205) | ||||
Molecular_info | Corresponding_CDS | T24H10.7a | |||||
T24H10.7b | |||||||
T24H10.7c | |||||||
T24H10.7d | |||||||
T24H10.7e | |||||||
T24H10.7f | |||||||
T24H10.7g | |||||||
T24H10.7h | |||||||
T24H10.7i | |||||||
Corresponding_CDS_history | T24H10.7:wp136 | ||||||
Corresponding_transcript | T24H10.7a.1 | ||||||
T24H10.7b.1 | |||||||
T24H10.7c.1 | |||||||
T24H10.7d.1 | |||||||
T24H10.7e.1 | |||||||
T24H10.7f.1 | |||||||
T24H10.7g.1 | |||||||
T24H10.7h.1 | |||||||
T24H10.7i.1 | |||||||
Other_sequence (42) | |||||||
Associated_feature (34) | |||||||
Gene_product_binds (375) | |||||||
Transcription_factor | WBTranscriptionFactor000109 | ||||||
WBTranscriptionFactor000501 | |||||||
Experimental_info | RNAi_result (33) | ||||||
Expr_pattern (14) | |||||||
Drives_construct | WBCnstr00012826 | ||||||
WBCnstr00014260 | |||||||
WBCnstr00014283 | |||||||
WBCnstr00014284 | |||||||
WBCnstr00014288 | |||||||
WBCnstr00014300 | |||||||
WBCnstr00014302 | |||||||
WBCnstr00030207 | |||||||
Construct_product | WBCnstr00030207 | ||||||
Microarray_results (48) | |||||||
Expression_cluster (184) | |||||||
Interaction (46) | |||||||
Map_info | Map | II | Position | 1.04759 | Error | 0.001496 | |
Positive | Positive_clone | T24H10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00025433 | ||||||
WBPaper00025575 | |||||||
WBPaper00028802 | |||||||
WBPaper00031111 | |||||||
WBPaper00033939 | |||||||
WBPaper00034543 | |||||||
WBPaper00034689 | |||||||
WBPaper00035989 | |||||||
WBPaper00039041 | |||||||
WBPaper00041960 | |||||||
WBPaper00042067 | |||||||
WBPaper00043072 | |||||||
WBPaper00044281 | |||||||
WBPaper00044399 | |||||||
WBPaper00046151 | |||||||
WBPaper00047745 | |||||||
WBPaper00049734 | |||||||
WBPaper00051455 | |||||||
WBPaper00051670 | |||||||
WBPaper00058109 | |||||||
WBPaper00060358 | |||||||
WBPaper00061115 | |||||||
WBPaper00064212 | |||||||
WBPaper00064229 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |