Predicted to enable proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Is an ortholog of human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2).