WormBase Tree Display for Gene: WBGene00006491

WBGene00006491 SMap: S_parent: Sequence: ZK809
  Identity: Version: 2
    Name: CGC_name: acl-3 Person_evidence: WBPerson1105
      Sequence_name: ZK809.2
      Molecular_name: ZK809.2
        ZK809.2.1
        CE46102
      Other_name: tag-145
        CELE_ZK809.2 Accession_evidence: NDB BX284604
      Public_name: acl-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 02 Jul 2004 16:55:44 WBPerson1971 Name_change: CGC_name: acl-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acl
    Allele (18)
    Strain: WBStrain00035829
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00062602 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00073567 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00028433 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00156776 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00092859 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00135293 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00143406 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00227813 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g8241 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g14415 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g20555 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g575 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g6510 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP29.g656 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g7769 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9906 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13701 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g16181 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g20059 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g764 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00384.g10085 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-acl-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g13311 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00092.g4019 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_21329 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014131 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08952 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g17939 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40324400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g11903 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00241354 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00263588 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00290173 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000006344 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0026619 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-684 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11577 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1588532 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: acl-3 encodes a glycerol-3-phosphate acyltransferase that is orthologous to human tafazzin (TAZ; OMIM:300394, mutated in Barth syndrome); by homology, ACL-3 is predicted to be a mitochondrial protein that plays a role in triacylglycerol metabolism; acl-3 expression shows some degree of dauer-specific induction. Paper_evidence: WBPaper00004103
            WBPaper00005654
            WBPaper00024497
            WBPaper00025054
            WBPaper00032488
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 22 Mar 2013 00:00:00
      Automated_description: Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity. Predicted to be involved in cardiolipin acyl-chain remodeling and inner mitochondrial membrane organization. Predicted to be located in mitochondrial membrane. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Is an ortholog of human TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0050476 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11577)
      DOID:12930 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11577)
  Molecular_info: Corresponding_CDS: ZK809.2
    Corresponding_CDS_history: ZK809.2:wp225
    Corresponding_transcript: ZK809.2.1
    Other_sequence (17)
    Associated_feature (5)
  Experimental_info: RNAi_result: WBRNAi00059726 Inferred_automatically: RNAi_primary
      WBRNAi00062499 Inferred_automatically: RNAi_primary
      WBRNAi00022172 Inferred_automatically: RNAi_primary
      WBRNAi00038443 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010803
      Expr1032654
      Expr1163147
      Expr2009154
      Expr2027391
    Drives_construct: WBCnstr00034339
    Construct_product: WBCnstr00034339
    Microarray_results (21)
    Expression_cluster (129)
    Interaction (36)
  Map_info: Map: IV Position: 5.10764 Error: 0.005571
    Positive: Positive_clone: ZK809 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4270
        4289
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00056678
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene