WormBase Tree Display for Gene: WBGene00006496
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| WBGene00006496 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 6 | |||||||
| Name | CGC_name | cgef-1 | Person_evidence | WBPerson3190 | |||||
| Sequence_name | C14A11.3 | ||||||||
| Molecular_name | C14A11.3a | ||||||||
| C14A11.3a.1 | |||||||||
| CE08151 | |||||||||
| C14A11.3b | |||||||||
| CE47800 | |||||||||
| C14A11.3c | |||||||||
| CE41760 | |||||||||
| C14A11.3b.1 | |||||||||
| C14A11.3c.1 | |||||||||
| Other_name | tag-150 | Person_evidence | WBPerson201 | ||||||
| CELE_C14A11.3 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | cgef-1 | ||||||||
| DB_info | Database | AceView | gene | XD417 | |||||
| WormQTL | gene | WBGene00006496 | |||||||
| WormFlux | gene | WBGene00006496 | |||||||
| NDB | locus_tag | CELE_C14A11.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006496|UniProtKB=H2KYI7 | |||||||
| family | PTHR22826 | ||||||||
| NCBI | gene | 180571 | |||||||
| RefSeq | protein | NM_171641.6 | |||||||
| NM_001129633.5 | |||||||||
| NM_171642.7 | |||||||||
| TREEFAM | TREEFAM_ID | TF332360 | |||||||
| TrEMBL | UniProtAcc | H2KYI7 | |||||||
| H2KYI8 | |||||||||
| O02134 | |||||||||
| UniProt_GCRP | UniProtAcc | H2KYI7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 28 May 2004 13:57:59 | WBPerson1971 | Event | Acquires_merge | WBGene00015749 | ||||
| 3 | 18 Jul 2008 10:54:16 | WBPerson2970 | Name_change | CGC_name | cgef-1 | ||||
| Other_name | tag-150 | ||||||||
| 4 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00194671 | ||||
| 5 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00018887 | ||||
| 6 | 13 Aug 2012 10:31:28 | WBPerson1849 | Event | Acquires_merge | WBGene00018889 | ||||
| Acquires_merge | WBGene00015749 | ||||||||
| WBGene00194671 | |||||||||
| WBGene00018887 | |||||||||
| WBGene00018889 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cgef | ||||||||
| Allele (410) | |||||||||
| Strain | WBStrain00035827 | ||||||||
| WBStrain00040403 | |||||||||
| WBStrain00040404 | |||||||||
| WBStrain00040405 | |||||||||
| WBStrain00040406 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021671 | ||||||||
| 00021672 | |||||||||
| 00021673 | |||||||||
| 00021674 | |||||||||
| 00021675 | |||||||||
| 00021676 | |||||||||
| 00114153 | |||||||||
| Ortholog (66) | |||||||||
| Paralog | WBGene00006805 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00022391 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WBGene00015704 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00006887 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00009337 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010111 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010776 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | cgef-1 encodes a putative guanine nucleotide exchange factor (GEF) and positively regulates CDC-42 during asymmetric division in the embryo; cgef-1 also affects the localization of PAR proteins in the embryo; since cgef-1 mutants exhibit mild phenotypes, cgef-1 may function redundantly with other GEFs to regulate CDC-42 function; CGEF-1 expressed under germline regulatory control is enriched in the nucleoplasm and cell cortex and localizes to the cytoplasm. | Paper_evidence | WBPaper00035488 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 04 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable guanyl-nucleotide exchange factor activity. Involved in protein localization. Located in cell cortex and nucleoplasm. Expressed in hermaphrodite gonad; neurons; somatic gonad precursor; and vulva. Is an ortholog of human MCF2 (MCF.2 cell line derived transforming sequence); MCF2L (MCF.2 cell line derived transforming sequence like); and MCF2L2 (MCF.2 cell line derived transforming sequence-like 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C14A11.3a | |||||||
| C14A11.3b | |||||||||
| C14A11.3c | |||||||||
| Corresponding_CDS_history | C14A11.3b:wp233 | ||||||||
| Corresponding_transcript | C14A11.3a.1 | ||||||||
| C14A11.3b.1 | |||||||||
| C14A11.3c.1 | |||||||||
| Other_sequence (12) | |||||||||
| Associated_feature (29) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00048514 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00048515 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00086072 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040462 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010705 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048512 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028854 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010704 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015737 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040461 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (13) | |||||||||
| Drives_construct (5) | |||||||||
| Construct_product | WBCnstr00013572 | ||||||||
| WBCnstr00017411 | |||||||||
| WBCnstr00037894 | |||||||||
| Antibody | WBAntibody00002109 | ||||||||
| Microarray_results | SMD_C14A11.3 | ||||||||
| SMD_C14A11.4 | |||||||||
| SMD_F55F1.1 | |||||||||
| 175009_at | |||||||||
| 184147_at | |||||||||
| 184775_at | |||||||||
| 192821_at | |||||||||
| A_12_P100534 | |||||||||
| A_12_P107295 | |||||||||
| A_12_P114693 | |||||||||
| A_12_P158615 | |||||||||
| Aff_C14A11.3 | |||||||||
| Aff_C14A11.4 | |||||||||
| Aff_F55F1.1 | |||||||||
| GPL13394_WBGene00006496 | |||||||||
| GPL13394_WBGene00018887 | |||||||||
| GPL13394_WBGene00018889 | |||||||||
| GPL13914_C14A11.3 | |||||||||
| GPL13914_F55F1.1 | |||||||||
| GPL13914_F55F1.3 | |||||||||
| GPL14144_C14A11.3b_1632-1691_0.927_4_C | |||||||||
| GPL14144_C14A11.3b_1771-1830_0.964_1_A | |||||||||
| GPL14144_C14A11.3b_1886-1945_0.951_2_B | |||||||||
| GPL14144_F55F1.1_155-214_0.950_2_C | |||||||||
| GPL14144_F55F1.1_198-257_0.970_1_B | |||||||||
| GPL14144_F55F1.1_27-86_0.906_10_A | |||||||||
| GPL14144_F55F1.3_150-209_0.937_2_B | |||||||||
| GPL14144_F55F1.3_244-303_0.935_6_C | |||||||||
| GPL14144_F55F1.3_50-109_0.941_1_A | |||||||||
| GPL19516_CGZ0004481 | |||||||||
| GPL19516_CGZ0004482 | |||||||||
| GPL19516_CGZ0004483 | |||||||||
| GPL19516_CGZ0011505 | |||||||||
| GPL19516_CGZ0011506 | |||||||||
| GPL21109_C14A11.3b | |||||||||
| GPL3518_CE08151 | |||||||||
| GPL3518_CE30147 | |||||||||
| GPL3518_CE30148 | |||||||||
| GPL3518_CE30861 | |||||||||
| GPL8304_CE_WBGene00006496_A | |||||||||
| GPL8304_CE_WBGene00006496_B | |||||||||
| GPL8304_CE_WBGene00006496_C | |||||||||
| GPL8304_CE_WBGene00018887_A | |||||||||
| GPL8304_CE_WBGene00018889_A | |||||||||
| GPL8673_C14A11_3aP00013 | |||||||||
| GPL8673_C14A11_3aP00015 | |||||||||
| GPL8673_C14A11_3aP00023 | |||||||||
| GPL8673_C14A11_3bP00518 | |||||||||
| GPL8673_C14A11_3bP00549 | |||||||||
| GPL8673_C14A11_3bP01501 | |||||||||
| GPL8673_F55F1_1P00041 | |||||||||
| GPL8673_F55F1_1P00045 | |||||||||
| GPL8673_F55F1_1P00186 | |||||||||
| GPL8673_F55F1_3P00062 | |||||||||
| GPL8673_F55F1_3P00147 | |||||||||
| GPL8673_F55F1_3P00248 | |||||||||
| GPL9450_C14A11.3a | |||||||||
| GPL9450_C14A11.3b | |||||||||
| GPL9450_F55F1.1 | |||||||||
| GPL9450_F55F1.3 | |||||||||
| cea2.3.02992 | |||||||||
| cea2.d.00631 | |||||||||
| cea2.i.54843 | |||||||||
| cea2.p.133632 | |||||||||
| cea2.p.147324 | |||||||||
| Expression_cluster (179) | |||||||||
| Interaction | WBInteraction000427331 | ||||||||
| WBInteraction000504195 | |||||||||
| WBInteraction000504198 | |||||||||
| WBInteraction000504199 | |||||||||
| WBInteraction000504200 | |||||||||
| WBInteraction000519968 | |||||||||
| WBInteraction000551256 | |||||||||
| WBInteraction000556753 | |||||||||
| Map_info | Map | X | Position | -13.036 | Error | 0.227099 | |||
| Positive | Positive_clone | C14A11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4942 | |||||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
