WormBase Tree Display for Gene: WBGene00003053
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WBGene00003053 | SMap | S_parent | Sequence | C03B1 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | lmp-1 | Person_evidence | WBPerson959 | |||||
Sequence_name | C03B1.12 | ||||||||
Molecular_name | C03B1.12 | ||||||||
C03B1.12.1 | |||||||||
CE03912 | |||||||||
Other_name | CELE_C03B1.12 | Accession_evidence | NDB | BX284606 | |||||
Public_name | lmp-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | lmp | ||||||||
Allele (23) | |||||||||
Strain | WBStrain00030579 | ||||||||
WBStrain00033050 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (34) | |||||||||
Paralog | WBGene00015471 | Caenorhabditis elegans | From_analysis | Panther | |||||
Structured_description | Concise_description | lmp-1 encodes a protein with similarity to vertebrate lysosome-associated membrane proteins CD68, and appears to be the only protein in C. elegans that has a GYXX (phi) vertebrate lysosomal targeting sequence at its carboxy terminus; LMP-1 is widely expressed in the early embryo, with later expression seen in the intestine, coelomocytes, and neurons; LMP-1 localizes to lysosomes and is recruited to phagosomes upon lysosomal fusion. | Paper_evidence | WBPaper00004254 | |||||
WBPaper00006472 | |||||||||
WBPaper00034674 | |||||||||
WBPaper00035888 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
WBPerson1843 | |||||||||
Date_last_updated | 07 Jan 2011 00:00:00 | ||||||||
Automated_description | Predicted to be involved in establishment of protein localization to organelle. Located in cytoplasmic vesicle and lysosomal membrane. Expressed in coelomocyte; germ line; and pharynx. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Is an ortholog of human LAMP2 (lysosomal associated membrane protein 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0050437 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6501) | ||||
DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6501) | ||||||
Molecular_info (4) | |||||||||
Experimental_info | RNAi_result | WBRNAi00090686 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00008328 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00039488 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00091312 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00065622 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00027912 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (12) | |||||||||
Drives_construct | WBCnstr00001778 | ||||||||
WBCnstr00006910 | |||||||||
WBCnstr00012218 | |||||||||
WBCnstr00036261 | |||||||||
Construct_product (14) | |||||||||
Antibody | WBAntibody00000297 | ||||||||
WBAntibody00002186 | |||||||||
WBAntibody00002423 | |||||||||
WBAntibody00002667 | |||||||||
Microarray_results | SMD_C03B1.12 | ||||||||
173193_s_at | |||||||||
187660_s_at | |||||||||
A_12_P105103 | |||||||||
A_12_P135275 | |||||||||
Aff_C03B1.12 | |||||||||
GPL13394_WBGene00003053 | |||||||||
GPL13914_C03B1.12 | |||||||||
GPL14144_C03B1.12_171-230_0.892_2_B | |||||||||
GPL14144_C03B1.12_399-458_0.885_3_C | |||||||||
GPL14144_C03B1.12_494-553_0.908_1_A | |||||||||
GPL19516_CGZ0002114 | |||||||||
GPL21109_C03B1.12 | |||||||||
GPL3518_CE03912 | |||||||||
GPL8304_CE_WBGene00003053_A | |||||||||
GPL8304_CE_WBGene00003053_C | |||||||||
GPL8673_C03B1_12P00023 | |||||||||
GPL8673_C03B1_12P00259 | |||||||||
GPL8673_C03B1_12P00550 | |||||||||
GPL9450_C03B1.12 | |||||||||
cea2.c.40959 | |||||||||
Expression_cluster (153) | |||||||||
Interaction (63) | |||||||||
WBProcess | WBbiopr:00000121 | ||||||||
Map_info | Map | X | Position | -2.92988 | Error | 0.003579 | |||
Positive | Positive_clone | C03B1 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (36) | |||||||||
Remark | Sequence connection from [Fire AZ, Kostich M, Fambrough DM] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |