WormBase Tree Display for Gene: WBGene00000122

WBGene00000122 SMap: S_parent: Sequence: M18
  Identity: Version: 1
    Name: CGC_name: aly-3 Person_evidence: WBPerson297
            WBPerson4981
      Sequence_name: M18.7
      Molecular_name: M18.7a
        M18.7a.1
        CE06198
        M18.7b
      Other_name: CELE_M18.7 Accession_evidence: NDB BX284604
      Public_name: aly-3
    DB_info: Database: WormQTL gene WBGene00000122
        WormFlux gene WBGene00000122
        NDB locus_tag CELE_M18.7
        Panther gene CAEEL|WormBase=WBGene00000122|UniProtKB=Q21559
          family PTHR19965
        NCBI gene 178157
        RefSeq protein NR_003454.1
            NM_001083228.6
        TREEFAM TREEFAM_ID TF313312
        TrEMBL UniProtAcc Q21559
        UniProt_GCRP UniProtAcc Q21559
        RNAcentral URSid URS0000253FBA
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aly
    Allele (33)
    RNASeq_FPKM (74)
    GO_annotation: 00072102
      00072103
      00072104
      00072105
      00106836
    Contained_in_operon: CEOP4496
    Ortholog: WBGene00028541 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00075068 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00156774 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00145339 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00136109 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00066295 Caenorhabditis remanei From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g11644 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g3527 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g3197 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g11030 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g7726 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6447 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g11033 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g958 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g8790 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g22653 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-aly-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold448.g1269 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00064.g3052 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04857 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_014246 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03166 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40238000 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12006 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00090238 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00111598 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00116154 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00275161 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00285690 Trichuris muris From_analysis: WormBase-Compara
      WBGene00298093 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0032439 Drosophila melanogaster From_analysis: OrthoFinder
            Panther
            SonicParanoid
      FB:FBgn0010774 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-070928-29 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      HGNC:19071 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1341044 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:1913144 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:1918238 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3649020 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782481 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:3782482 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782483 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782485 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782487 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
      MGI:3782493 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:3782524 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      MGI:5434648 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1594679 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
    Paralog: WBGene00000120 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00000121 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00015329 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: aly-3 encodes an RRM motif-containing protein orthologous to human THOC4 (OMIM:604171), and paralogous to ALY-1 and ALY-2; by orthology, ALY-3 is thought to promote recruitment of mRNA export factor to mRNAs; however, ALY-3 has no grossly obvious function in four-way RNAi assays of ALY-1/-3 and W04D2.6, and aly-3(RNAi) had no obvious effect on nuclear retention of tra-2 mRNA in the absence of TRA-1. Paper_evidence: WBPaper00030790
          Curator_confirmed: WBPerson567
          Date_last_updated: 09 Dec 2007 00:00:00
      Automated_description: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Is an ortholog of human ALYREF (Aly/REF export factor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: M18.7a
    Corresponding_transcript: M18.7b
      M18.7a.1
    Other_sequence (31)
    Associated_feature (12)
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr13880
      Expr1015108
      Expr1030068
      Expr1154717
      Expr2009318
      Expr2027554
    Drives_construct: WBCnstr00037716
    Construct_product: WBCnstr00037716
      WBCnstr00040228
    Microarray_results: SMD_M18.7
      193709_at
      A_12_P147690
      Aff_M18.7
      GPL13394_WBGene00000122
      GPL13914_M18.7
      GPL14144_M18.7a_149-208_0.918_6_C
      GPL14144_M18.7a_228-287_0.928_4_B
      GPL14144_M18.7a_663-722_0.947_1_A
      GPL19516_CGZ0011778
      GPL19516_CGZ0030224
      GPL19516_CGZ0030225
      GPL19516_CGZ0030226
      GPL21109_Cat_M18.7a.1
      GPL21109_M18.7a.1
      GPL3518_CE06198
      GPL8304_CE_WBGene00000122_A
      GPL8304_CE_WBGene00000122_B
      GPL8304_CE_WBGene00000122_C
      GPL8673_M18_7aP00206
      GPL8673_M18_7aP00549
      GPL8673_M18_7aP00556
      GPL9450_M18.7
      cea2.c.30515
    Expression_cluster (130)
    Interaction (34)
  Map_info: Map: IV Position: 5.72967 Error: 0.002435
    Positive: Positive_clone: M18 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5514
        5519
        5280
    Pseudo_map_position
  Reference: WBPaper00013477
    WBPaper00029295
    WBPaper00038491
    WBPaper00055090
    WBPaper00063792
    WBPaper00064012
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene