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WormBase Tree Display for Gene: WBGene00013308

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Name Class

WBGene00013308SMapS_parentSequenceY57G11C
IdentityVersion4
Name (5)
DB_infoDatabaseWormQTLgeneWBGene00013308
WormFluxgeneWBGene00013308
NDBlocus_tagCELE_Y57G11C.12
PanthergeneCAEEL|WormBase=WBGene00013308|UniProtKB=O18236
familyPTHR12964
NCBIgene36805062
RefSeqproteinNM_001392444.1
TrEMBLUniProtAccO18236
UniProt_GCRPUniProtAccO18236
OMIMgene602138
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
231 Aug 2005 14:07:05WBPerson2970Name_changeCGC_namenuo-3
306 Mar 2018 14:43:22WBPerson4025EventSplit_intoWBGene00303007
416 Jan 2023 18:37:21WBPerson51134Name_changeOther_namendua-6
Split_intoWBGene00303007
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnuo
Allele (27)
StrainWBStrain00003089
WBStrain00055406
RNASeq_FPKM (74)
GO_annotation00031815
00031816
00031817
00031818
00031819
00031820
00031821
00031822
00031823
Contained_in_operonCEOP5614
Ortholog (28)
Structured_descriptionConcise_descriptionThe nuo-3 locus encodes two distinct, non-overlapping proteins: Y57G11C.12a (homologous to human C3orf10/BRICK1, a component of the WAVE1 complex) and Y57G11C.12b (a putativeNADH-ubiquinone oxidoreductase alpha subunit, homologous to human NDUFA6 [OMIM:602138]).Person_evidenceWBPerson242
Curator_confirmedWBPerson567
Date_last_updated12 May 2008 00:00:00
Automated_descriptionPredicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 33. Is an ortholog of human NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112097Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7690)
DOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7690)
Molecular_infoCorresponding_CDSY57G11C.12
Corresponding_CDS_historyY57G11C.12a:wp264
Y57G11C.12b:wp264
Corresponding_transcriptY57G11C.12.1
Y57G11C.12.2
Corresponding_transcript_historyY57G11C.12c:wp264
Associated_featureWBsf652383
WBsf981851
WBsf998642
WBsf231227
Experimental_infoRNAi_result (35)
Expr_patternChronogram977
Expr7077
Expr1012642
Expr1035936
Expr1161096
Expr2014529
Expr2032768
Drives_constructWBCnstr00003574
WBCnstr00029696
Construct_productWBCnstr00029696
Microarray_results (32)
Expression_cluster (107)
InteractionWBInteraction000032336
WBInteraction000049555
WBInteraction000111671
WBInteraction000111679
WBInteraction000111685
WBInteraction000111689
WBInteraction000111692
WBInteraction000111693
WBInteraction000111703
WBInteraction000111713
WBInteraction000111722
WBInteraction000111774
WBInteraction000144478
WBInteraction000153356
WBInteraction000153386
WBInteraction000153411
WBInteraction000153441
WBInteraction000153477
WBInteraction000153504
WBInteraction000153618
WBInteraction000153663
WBInteraction000154088
WBInteraction000154179
WBInteraction000155252
WBInteraction000155512
WBInteraction000155540
WBInteraction000155604
WBInteraction000155667
WBInteraction000155699
WBInteraction000155739
WBInteraction000155796
WBInteraction000155797
WBInteraction000155798
WBInteraction000155799
WBInteraction000155835
WBInteraction000155975
WBInteraction000156157
WBInteraction000156308
WBInteraction000156373
WBInteraction000156391
WBInteraction000156423
WBInteraction000156437
WBInteraction000156456
WBInteraction000157397
WBInteraction000157417
WBInteraction000157433
WBInteraction000157447
WBInteraction000157473
WBInteraction000157485
WBInteraction000157505
WBInteraction000157515
WBInteraction000157561
WBInteraction000157572
WBInteraction000157580
WBInteraction000157589
WBInteraction000157596
WBInteraction000157602
WBInteraction000184236
WBInteraction000193778
WBInteraction000198356
WBInteraction000204271
WBInteraction000218873
WBInteraction000222592
WBInteraction000247974
WBInteraction000252907
WBInteraction000299025
WBInteraction000319471
WBInteraction000325720
WBInteraction000372583
WBInteraction000380822
WBInteraction000386930
WBInteraction000392455
WBInteraction000416486
WBInteraction000438541
WBInteraction000439227
WBInteraction000444983
WBInteraction000518651
WBInteraction000536249
WBInteraction000536261
WBInteraction000536286
WBInteraction000556194
WBInteraction000558437
WBInteraction000559657
WBInteraction000561935
WBInteraction000566133
WBInteraction000568103
WBInteraction000572461
Map_infoMapIVPosition12.5086Error0.002306
PositivePositive_cloneY57G11CInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005928
WBPaper00026715
WBPaper00031194
WBPaper00033840
WBPaper00037471
WBPaper00038491
WBPaper00041233
WBPaper00048636
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene