WormBase Tree Display for Gene: WBGene00012553

WBGene00012553 SMap: S_parent: Sequence: Y37D8A
  Identity: Version: 3
    Name: CGC_name: cox-5A Person_evidence: WBPerson117
            WBPerson7169
      Sequence_name: Y37D8A.14
      Molecular_name: Y37D8A.14
        Y37D8A.14.1
        CE20218
      Other_name: cco-2 Person_evidence: WBPerson1157
        CELE_Y37D8A.14 Accession_evidence: NDB BX284603
      Public_name: cox-5A
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 31 Aug 2005 14:07:05 WBPerson2970 Name_change: CGC_name: cco-2
        3 05 Sep 2017 13:25:30 WBPerson2970 Name_change: CGC_name: cox-5A
                Other_name: cco-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cox
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (38)
    Structured_description: Concise_description: cco-2 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit Va (COX Va); loss of cco-2 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. Paper_evidence: WBPaper00032427
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Nov 2010 00:00:00
      Automated_description: Predicted to enable metal ion binding activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX5A (cytochrome c oxidase subunit 5A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070505 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2267)
  Molecular_info: Corresponding_CDS: Y37D8A.14
    Corresponding_transcript: Y37D8A.14.1
    Other_sequence (143)
    Associated_feature (15)
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr1017887
      Expr1035556
      Expr1159398
      Expr2009765
      Expr2028005
    Microarray_results (26)
    Expression_cluster (116)
    Interaction: WBInteraction000034076
      WBInteraction000045811
      WBInteraction000106302
      WBInteraction000109820
      WBInteraction000110837
      WBInteraction000111293
      WBInteraction000111374
      WBInteraction000111433
      WBInteraction000116371
      WBInteraction000120694
      WBInteraction000144002
      WBInteraction000144587
      WBInteraction000153353
      WBInteraction000153383
      WBInteraction000153408
      WBInteraction000153438
      WBInteraction000153474
      WBInteraction000153615
      WBInteraction000154085
      WBInteraction000155601
      WBInteraction000155664
      WBInteraction000155696
      WBInteraction000155736
      WBInteraction000155761
      WBInteraction000155762
      WBInteraction000155763
      WBInteraction000156305
      WBInteraction000156434
      WBInteraction000179734
      WBInteraction000181797
      WBInteraction000220484
      WBInteraction000232949
      WBInteraction000233026
      WBInteraction000233956
      WBInteraction000235617
      WBInteraction000242803
      WBInteraction000248206
      WBInteraction000264006
      WBInteraction000279865
      WBInteraction000285560
      WBInteraction000297348
      WBInteraction000310276
      WBInteraction000314696
      WBInteraction000318862
      WBInteraction000319271
      WBInteraction000325605
      WBInteraction000333622
      WBInteraction000334020
      WBInteraction000336602
      WBInteraction000337014
      WBInteraction000340892
      WBInteraction000347485
      WBInteraction000352990
      WBInteraction000355459
      WBInteraction000379065
      WBInteraction000382979
      WBInteraction000382980
      WBInteraction000386930
      WBInteraction000389300
      WBInteraction000404638
      WBInteraction000404733
      WBInteraction000408384
      WBInteraction000419051
      WBInteraction000421186
      WBInteraction000421187
      WBInteraction000435194
      WBInteraction000436419
      WBInteraction000437389
      WBInteraction000442402
      WBInteraction000445281
      WBInteraction000448867
      WBInteraction000462728
      WBInteraction000463250
      WBInteraction000471278
      WBInteraction000502922
      WBInteraction000536346
      WBInteraction000536351
      WBInteraction000536356
      WBInteraction000537141
      WBInteraction000537458
      WBInteraction000537461
      WBInteraction000539697
      WBInteraction000542793
      WBInteraction000551866
      WBInteraction000552969
      WBInteraction000554011
      WBInteraction000558413
      WBInteraction000559575
      WBInteraction000562036
      WBInteraction000563737
      WBInteraction000566430
      WBInteraction000566709
      WBInteraction000572398
      WBInteraction000572563
      WBInteraction000583313
  Map_info: Map: III Position: 19.5686 Error: 0.139069
    Positive: Positive_clone: Y37D8A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (7)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene