WormBase Tree Display for Gene: WBGene00006376

WBGene00006376 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C24G6
  Identity: Version: 1
    Name: CGC_name: syp-2 Person_evidence: WBPerson1547
      Sequence_name: C24G6.1
      Molecular_name: C24G6.1
        C24G6.1.1
        CE17456
      Other_name: CELE_C24G6.1 Accession_evidence: NDB BX284605
      Public_name: syp-2
    DB_info: Database: AceView gene 5G17
        WormQTL gene WBGene00006376
        WormFlux gene WBGene00006376
        NDB locus_tag CELE_C24G6.1
        NCBI gene 178938
        RefSeq protein NM_072061.7
        TREEFAM TREEFAM_ID TF333776
        TrEMBL UniProtAcc O76388
        UniProt_GCRP UniProtAcc O76388
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: syp
    Allele (21)
    Strain: WBStrain00000287
      WBStrain00034784
    RNASeq_FPKM (74)
    GO_annotation (8)
    Ortholog (18)
    Structured_description: Concise_description: syp-2 encodes a coiled-coil protein; during meiosis, syp-2 activity is required for the normal progression of chromosome organization in the nucleus, for maintaining stable pairing between homologous chromosomes subsequent to initial pairing, and for productive crossover events and chiasmata formation; SYP-2 localizes to the region between paired homologous chromosomes during pachytene and disappears from this interface by late diakinesis, suggesting that SYP-2 is a structural component of the central element of the synaptonemal complex (SC); SYP-2 localization to the SC is dependent upon activity of HIM-3 and REC-8, meiosis-specific axis components, while SYP-1, an additional SC component, and SYP-2 are interdependent for localization to the SC. Paper_evidence: WBPaper00005486
            WBPaper00006086
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Mar 2009 00:00:00
      Automated_description: Involved in positive regulation of reciprocal meiotic recombination and synaptonemal complex assembly. Located in central element. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C24G6.1
    Corresponding_transcript: C24G6.1.1
    Other_sequence: FD517546.1
      CSC02241_1
    Associated_feature: WBsf646810
      WBsf646811
      WBsf661265
      WBsf231769
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr2680
      Expr1022707
      Expr1032574
      Expr1145134
      Expr1200231
      Expr2017185
      Expr2035321
    Drives_construct: WBCnstr00006076
      WBCnstr00034383
    Construct_product: WBCnstr00006065
      WBCnstr00006076
      WBCnstr00016719
      WBCnstr00034383
    Antibody: WBAntibody00000673
      WBAntibody00002302
      WBAntibody00002754
      WBAntibody00002943
    Microarray_results (18)
    Expression_cluster (150)
    Interaction: WBInteraction000002196
      WBInteraction000008950
      WBInteraction000008951
      WBInteraction000031764
      WBInteraction000051941
      WBInteraction000051942
      WBInteraction000104004
      WBInteraction000104643
      WBInteraction000105918
      WBInteraction000108914
      WBInteraction000109948
      WBInteraction000110473
      WBInteraction000112331
      WBInteraction000113284
      WBInteraction000118209
      WBInteraction000119467
      WBInteraction000120249
      WBInteraction000122349
      WBInteraction000124038
      WBInteraction000124678
      WBInteraction000124822
      WBInteraction000124887
      WBInteraction000125129
      WBInteraction000125246
      WBInteraction000125716
      WBInteraction000133247
      WBInteraction000134123
      WBInteraction000134728
      WBInteraction000135424
      WBInteraction000136404
      WBInteraction000136918
      WBInteraction000137053
      WBInteraction000137340
      WBInteraction000137780
      WBInteraction000138394
      WBInteraction000138894
      WBInteraction000141156
      WBInteraction000141257
      WBInteraction000141780
      WBInteraction000143436
      WBInteraction000144143
      WBInteraction000144645
      WBInteraction000145135
      WBInteraction000145334
      WBInteraction000148334
      WBInteraction000148512
      WBInteraction000149062
      WBInteraction000149263
      WBInteraction000149590
      WBInteraction000150305
      WBInteraction000150777
      WBInteraction000151466
      WBInteraction000151577
      WBInteraction000157186
      WBInteraction000160564
      WBInteraction000161189
      WBInteraction000161358
      WBInteraction000162017
      WBInteraction000165184
      WBInteraction000167991
      WBInteraction000170322
      WBInteraction000170463
      WBInteraction000172384
      WBInteraction000174984
      WBInteraction000175323
      WBInteraction000175692
      WBInteraction000175974
      WBInteraction000176489
      WBInteraction000176997
      WBInteraction000177924
      WBInteraction000179120
      WBInteraction000179189
      WBInteraction000179679
      WBInteraction000181431
      WBInteraction000181472
      WBInteraction000181478
      WBInteraction000183685
      WBInteraction000183994
      WBInteraction000184596
      WBInteraction000186201
      WBInteraction000186645
      WBInteraction000187335
      WBInteraction000187866
      WBInteraction000189473
      WBInteraction000189772
      WBInteraction000191354
      WBInteraction000191436
      WBInteraction000193208
      WBInteraction000193951
      WBInteraction000194825
      WBInteraction000195355
      WBInteraction000196134
      WBInteraction000196173
      WBInteraction000196330
      WBInteraction000196378
      WBInteraction000197883
      WBInteraction000198467
      WBInteraction000198991
      WBInteraction000199636
      WBInteraction000200804
      WBInteraction000201140
      WBInteraction000202100
      WBInteraction000203469
      WBInteraction000204376
      WBInteraction000204603
      WBInteraction000204964
      WBInteraction000206007
      WBInteraction000206807
      WBInteraction000208515
      WBInteraction000209666
      WBInteraction000209875
      WBInteraction000210267
      WBInteraction000211037
      WBInteraction000211085
      WBInteraction000211707
      WBInteraction000214749
      WBInteraction000215013
      WBInteraction000215765
      WBInteraction000215790
      WBInteraction000216427
      WBInteraction000218325
      WBInteraction000219916
      WBInteraction000220139
      WBInteraction000220179
      WBInteraction000220458
      WBInteraction000223757
      WBInteraction000225072
      WBInteraction000225936
      WBInteraction000225995
      WBInteraction000226409
      WBInteraction000230378
      WBInteraction000231086
      WBInteraction000231356
      WBInteraction000231930
      WBInteraction000232170
      WBInteraction000235546
      WBInteraction000235629
      WBInteraction000236668
      WBInteraction000240300
      WBInteraction000242430
      WBInteraction000242640
      WBInteraction000244333
      WBInteraction000245710
      WBInteraction000245996
      WBInteraction000246809
      WBInteraction000246862
      WBInteraction000248050
      WBInteraction000248239
      WBInteraction000248571
      WBInteraction000250395
      WBInteraction000251913
      WBInteraction000254650
      WBInteraction000255388
      WBInteraction000258008
      WBInteraction000259455
      WBInteraction000260196
      WBInteraction000260468
      WBInteraction000261511
      WBInteraction000263829
      WBInteraction000263877
      WBInteraction000264128
      WBInteraction000264655
      WBInteraction000266174
      WBInteraction000266394
      WBInteraction000266456
      WBInteraction000266556
      WBInteraction000267434
      WBInteraction000268046
      WBInteraction000270626
      WBInteraction000270835
      WBInteraction000271135
      WBInteraction000274451
      WBInteraction000274599
      WBInteraction000276214
      WBInteraction000277569
      WBInteraction000279278
      WBInteraction000279447
      WBInteraction000279871
      WBInteraction000280954
      WBInteraction000281726
      WBInteraction000281806
      WBInteraction000282071
      WBInteraction000282094
      WBInteraction000283640
      WBInteraction000283782
      WBInteraction000283847
      WBInteraction000284243
      WBInteraction000287786
      WBInteraction000288125
      WBInteraction000288518
      WBInteraction000288611
      WBInteraction000288643
      WBInteraction000289143
      WBInteraction000289195
      WBInteraction000289364
      WBInteraction000289468
      WBInteraction000290267
      WBInteraction000290526
      WBInteraction000291219
      WBInteraction000291639
      WBInteraction000292260
      WBInteraction000292634
      WBInteraction000292893
      WBInteraction000296031
      WBInteraction000296789
      WBInteraction000297212
      WBInteraction000298133
      WBInteraction000303465
      WBInteraction000303903
      WBInteraction000306331
      WBInteraction000306401
      WBInteraction000306560
      WBInteraction000308382
      WBInteraction000310522
      WBInteraction000310639
      WBInteraction000311591
      WBInteraction000315135
      WBInteraction000316737
      WBInteraction000320289
      WBInteraction000321746
      WBInteraction000324729
      WBInteraction000325839
      WBInteraction000327715
      WBInteraction000328094
      WBInteraction000331561
      WBInteraction000332759
      WBInteraction000332807
      WBInteraction000334820
      WBInteraction000340091
      WBInteraction000341990
      WBInteraction000342440
      WBInteraction000342455
      WBInteraction000343096
      WBInteraction000346710
      WBInteraction000347137
      WBInteraction000347543
      WBInteraction000348935
      WBInteraction000351555
      WBInteraction000353085
      WBInteraction000353178
      WBInteraction000355760
      WBInteraction000357130
      WBInteraction000360055
      WBInteraction000360274
      WBInteraction000360450
      WBInteraction000362452
      WBInteraction000366881
      WBInteraction000367270
      WBInteraction000368213
      WBInteraction000368521
      WBInteraction000368693
      WBInteraction000369187
      WBInteraction000369835
      WBInteraction000370515
      WBInteraction000372264
      WBInteraction000373943
      WBInteraction000374080
      WBInteraction000374461
      WBInteraction000375422
      WBInteraction000377171
      WBInteraction000378718
      WBInteraction000379305
      WBInteraction000382239
      WBInteraction000382442
      WBInteraction000383445
      WBInteraction000385097
      WBInteraction000385466
      WBInteraction000386814
      WBInteraction000388566
      WBInteraction000389033
      WBInteraction000391525
      WBInteraction000391621
      WBInteraction000393984
      WBInteraction000395997
      WBInteraction000396478
      WBInteraction000397574
      WBInteraction000398113
      WBInteraction000398997
      WBInteraction000399282
      WBInteraction000399371
      WBInteraction000400376
      WBInteraction000400977
      WBInteraction000402658
      WBInteraction000403894
      WBInteraction000405358
      WBInteraction000409947
      WBInteraction000410548
      WBInteraction000411268
      WBInteraction000412609
      WBInteraction000413930
      WBInteraction000414050
      WBInteraction000414671
      WBInteraction000415378
      WBInteraction000418543
      WBInteraction000419309
      WBInteraction000422705
      WBInteraction000423229
      WBInteraction000423622
      WBInteraction000424169
      WBInteraction000427354
      WBInteraction000428192
      WBInteraction000431235
      WBInteraction000431626
      WBInteraction000433957
      WBInteraction000435035
      WBInteraction000436856
      WBInteraction000440191
      WBInteraction000445577
      WBInteraction000445708
      WBInteraction000446933
      WBInteraction000449908
      WBInteraction000451378
      WBInteraction000452293
      WBInteraction000453032
      WBInteraction000455664
      WBInteraction000455879
      WBInteraction000458205
      WBInteraction000459632
      WBInteraction000459684
      WBInteraction000460534
      WBInteraction000460887
      WBInteraction000461078
      WBInteraction000461639
      WBInteraction000461663
      WBInteraction000462648
      WBInteraction000504101
      WBInteraction000522497
      WBInteraction000522498
      WBInteraction000522500
      WBInteraction000547352
      WBInteraction000551290
      WBInteraction000560295
      WBInteraction000567053
      WBInteraction000567054
      WBInteraction000567055
      WBInteraction000567056
      WBInteraction000567057
      WBInteraction000567058
      WBInteraction000567059
      WBInteraction000567060
      WBInteraction000567061
      WBInteraction000567062
      WBInteraction000567063
      WBInteraction000567064
      WBInteraction000567065
      WBInteraction000567066
      WBInteraction000567067
      WBInteraction000567068
      WBInteraction000567069
      WBInteraction000567070
      WBInteraction000567071
      WBInteraction000567095
      WBInteraction000585553
      WBInteraction000585555
  Map_info: Map: V Position: -1.67459 Error: 0.0238
    Positive: Positive_clone: C24G6 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4717
        4944
    Pseudo_map_position
  Reference (54)
  Remark: Sequence connection from [Villeneuve AM]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene