prx-1 encodes a predicted peroxin, a subfamily 2 member of the AAA (ATPases Associated with diverse cellular Activities) family that affects growth in one large-scale RNAi screen; expressed in intestinal cells throughout development.
Predicted to enable ATP hydrolysis activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to be located in cytosol and peroxisomal membrane. Human ortholog(s) of this gene implicated in Heimler syndrome 1; peroxisome biogenesis disorder 1A; and peroxisome biogenesis disorder 1B. Is an ortholog of human PEX1 (peroxisomal biogenesis factor 1).
Sequence connection from [Motley AM, Plasterk RHA], 02/06/13 krb.
The connected sequence (C11H1.4) was previously C11H1.6 (the C11H1.4 gene was extended and incorporated C11H1.6). krb
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.