WormBase Tree Display for Gene: WBGene00004061

WBGene00004061 Evidence: Person_evidence: WBPerson583
      WBPerson36
    CGC_data_submission
  SMap: S_parent: Sequence: C06A12
  Identity: Version: 1
    Name: CGC_name: pmp-4 Person_evidence: WBPerson36
      Sequence_name: T02D1.5
      Molecular_name: T02D1.5
        T02D1.5.1
        CE16325
      Other_name: tag-14 CGC_data_submission
        CELE_T02D1.5 Accession_evidence: NDB BX284604
      Public_name: pmp-4
    DB_info: Database: AceView gene 4S346
        WormQTL gene WBGene00004061
        NDB locus_tag CELE_T02D1.5
        Panther gene CAEEL|WormBase=WBGene00004061|UniProtKB=O45730
          family PTHR11384
        NCBI gene 24104835
        RefSeq protein NM_001306751.3
        TREEFAM TREEFAM_ID TF105205
        TrEMBL UniProtAcc O45730
        UniProt_GCRP UniProtAcc O45730
        OMIM gene 300371
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pmp
    Allele (108)
    Strain: WBStrain00001302
      WBStrain00031414
      WBStrain00035573
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (42)
    Paralog: WBGene00004058 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004059 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004060 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004062 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: The pmp-4 gene encodes a homolog of human ALD, which when mutated leads to X-linked adrenoleukodystrophy (OMIM:300100). Paper_evidence: WBPaper00004103
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable ATP binding activity; ATPase-coupled transmembrane transporter activity; and long-chain fatty acid transporter activity. Predicted to be involved in fatty acid catabolic process; long-chain fatty acid import into peroxisome; and peroxisome organization. Predicted to be located in peroxisomal membrane. Used to study adrenoleukodystrophy. Human ortholog(s) of this gene implicated in adrenoleukodystrophy. Is an ortholog of human ABCD1 (ATP binding cassette subfamily D member 1) and ABCD2 (ATP binding cassette subfamily D member 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info (2)
  Models_disease_asserted: WBDOannot00000840
    WBDOannot00000841
  Molecular_info: Corresponding_CDS: T02D1.5
    Corresponding_transcript: T02D1.5.1
    Other_sequence (31)
    Associated_feature: WBsf652423
      WBsf668588
      WBsf717215
  Experimental_info: RNAi_result: WBRNAi00018023 Inferred_automatically: RNAi_primary
      WBRNAi00002422 Inferred_automatically: RNAi_primary
      WBRNAi00035055 Inferred_automatically: RNAi_primary
      WBRNAi00052205 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6572
      Expr15211
      Expr15212
      Expr15213
      Expr1018172
      Expr1031959
      Expr1155835
      Expr2014975
      Expr2033210
    Drives_construct: WBCnstr00002195
      WBCnstr00035715
      WBCnstr00042070
      WBCnstr00042071
      WBCnstr00042089
    Construct_product: WBCnstr00035715
      WBCnstr00042071
      WBCnstr00042089
    Antibody: WBAntibody00002912
    Microarray_results (22)
    Expression_cluster (164)
    Interaction: WBInteraction000037170
      WBInteraction000038228
      WBInteraction000038229
      WBInteraction000112256
      WBInteraction000112257
      WBInteraction000138155
      WBInteraction000189561
      WBInteraction000201430
      WBInteraction000201432
      WBInteraction000203329
      WBInteraction000210577
      WBInteraction000210881
      WBInteraction000221527
      WBInteraction000226216
      WBInteraction000229805
      WBInteraction000239139
      WBInteraction000246992
      WBInteraction000248238
      WBInteraction000250754
      WBInteraction000252187
      WBInteraction000253925
      WBInteraction000263692
      WBInteraction000265621
      WBInteraction000265788
      WBInteraction000269923
      WBInteraction000273297
      WBInteraction000276252
      WBInteraction000284561
      WBInteraction000284996
      WBInteraction000287954
      WBInteraction000289114
      WBInteraction000290436
      WBInteraction000291805
      WBInteraction000293628
      WBInteraction000294342
      WBInteraction000298282
      WBInteraction000301185
      WBInteraction000305939
      WBInteraction000305967
      WBInteraction000306625
      WBInteraction000315097
      WBInteraction000328260
      WBInteraction000328973
      WBInteraction000329766
      WBInteraction000331119
      WBInteraction000331893
      WBInteraction000333012
      WBInteraction000361500
      WBInteraction000365557
      WBInteraction000370033
      WBInteraction000376620
      WBInteraction000376647
      WBInteraction000380683
      WBInteraction000380809
      WBInteraction000392856
      WBInteraction000407685
      WBInteraction000409123
      WBInteraction000412223
      WBInteraction000412224
      WBInteraction000412681
      WBInteraction000419809
      WBInteraction000420969
      WBInteraction000422753
      WBInteraction000423928
      WBInteraction000424691
      WBInteraction000426964
      WBInteraction000427589
      WBInteraction000430779
      WBInteraction000433021
      WBInteraction000439225
      WBInteraction000441792
      WBInteraction000442393
      WBInteraction000442394
      WBInteraction000443574
      WBInteraction000451363
      WBInteraction000457023
      WBInteraction000458692
      WBInteraction000461685
      WBInteraction000463278
      WBInteraction000463431
      WBInteraction000463668
      WBInteraction000463669
      WBInteraction000465588
      WBInteraction000466817
      WBInteraction000466860
      WBInteraction000466861
      WBInteraction000467289
      WBInteraction000467464
      WBInteraction000467896
      WBInteraction000469036
      WBInteraction000469113
      WBInteraction000469114
      WBInteraction000471415
      WBInteraction000471505
      WBInteraction000473606
      WBInteraction000474128
      WBInteraction000474831
      WBInteraction000504169
      WBInteraction000562948
      WBInteraction000564154
  Map_info: Map: IV Position: 16.8463 Error: 0.037163
    Positive: Positive_clone: T02D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4778
        4901
    Pseudo_map_position
  Reference: WBPaper00016821
    WBPaper00027644
    WBPaper00031484
    WBPaper00038491
    WBPaper00047097
    WBPaper00055090
    WBPaper00059252
    WBPaper00060821
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene