WormBase Tree Display for Gene: WBGene00000209

WBGene00000209 SMap: S_parent: Sequence: K07A12
  Identity: Version: 1
    Name (5)
    DB_info: Database: AceView gene 1J269
        WormQTL gene WBGene00000209
        WormFlux gene WBGene00000209
        NDB locus_tag CELE_K07A12.3
        Panther gene CAEEL|WormBase=WBGene00000209|UniProtKB=P90921
          family PTHR12386
        NCBI gene 172673
        RefSeq protein NM_059951.8
        SwissProt UniProtAcc P90921
        TREEFAM TREEFAM_ID TF313978
        UniProt_GCRP UniProtAcc P90921
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: asg
    Allele (16)
    Strain: WBStrain00037232
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (39)
    Paralog: WBGene00000210 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: asg-1 encodes a homolog of the proton-translocating F0 ATP synthase complex subunit g; by homology, ASG-1 is predicted to function in ATP synthesis, although its precise role in ATP anabolism is not yet known; in C. elegans, asg-1 activity is required for transposon silencing in the germline, suggesting that healthy energy metabolism is necessary for this process; in addition, large-scale RNAi screens indicate that asg-1 activity is required for embryonic and germline development, normal post-embryonic growth rates, and normal body morphology. Paper_evidence: WBPaper00004402
            WBPaper00006028
            WBPaper00006395
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial membrane. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human ATP5MG (ATP synthase membrane subunit g). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14247)
  Molecular_info: Corresponding_CDS: K07A12.3
    Corresponding_transcript: K07A12.3.1
    Other_sequence (100)
    Associated_feature: WBsf643541
      WBsf643542
      WBsf218193
  Experimental_info: RNAi_result (21)
    Expr_pattern: Expr1013546
      Expr1030128
      Expr1153799
      Expr2009449
      Expr2027686
    Drives_construct: WBCnstr00037663
    Construct_product: WBCnstr00037663
    Microarray_results (19)
    Expression_cluster (140)
    Interaction: WBInteraction000107410
      WBInteraction000107413
      WBInteraction000107416
      WBInteraction000107417
      WBInteraction000124015
      WBInteraction000127712
      WBInteraction000127719
      WBInteraction000127724
      WBInteraction000131519
      WBInteraction000132619
      WBInteraction000133464
      WBInteraction000135937
      WBInteraction000148479
      WBInteraction000153401
      WBInteraction000153402
      WBInteraction000153403
      WBInteraction000153404
      WBInteraction000153405
      WBInteraction000153406
      WBInteraction000153407
      WBInteraction000153408
      WBInteraction000153409
      WBInteraction000153410
      WBInteraction000153411
      WBInteraction000153412
      WBInteraction000153413
      WBInteraction000153414
      WBInteraction000153415
      WBInteraction000153416
      WBInteraction000153417
      WBInteraction000153418
      WBInteraction000153419
      WBInteraction000153420
      WBInteraction000153421
      WBInteraction000153422
      WBInteraction000153520
      WBInteraction000153596
      WBInteraction000154073
      WBInteraction000154206
      WBInteraction000155166
      WBInteraction000155213
      WBInteraction000155285
      WBInteraction000155431
      WBInteraction000155555
      WBInteraction000155580
      WBInteraction000155895
      WBInteraction000155930
      WBInteraction000156014
      WBInteraction000156140
      WBInteraction000156333
      WBInteraction000164651
      WBInteraction000171204
      WBInteraction000171718
      WBInteraction000174653
      WBInteraction000182983
      WBInteraction000187111
      WBInteraction000190351
      WBInteraction000197998
      WBInteraction000198732
      WBInteraction000199377
      WBInteraction000200109
      WBInteraction000200777
      WBInteraction000201807
      WBInteraction000210980
      WBInteraction000215299
      WBInteraction000226614
      WBInteraction000232103
      WBInteraction000236970
      WBInteraction000237365
      WBInteraction000239234
      WBInteraction000245259
      WBInteraction000247520
      WBInteraction000260196
      WBInteraction000260559
      WBInteraction000265403
      WBInteraction000273912
      WBInteraction000278202
      WBInteraction000284548
      WBInteraction000287534
      WBInteraction000297582
      WBInteraction000310032
      WBInteraction000311737
      WBInteraction000312471
      WBInteraction000315694
      WBInteraction000320384
      WBInteraction000321051
      WBInteraction000323804
      WBInteraction000324790
      WBInteraction000326037
      WBInteraction000331525
      WBInteraction000332593
      WBInteraction000336239
      WBInteraction000342226
      WBInteraction000345883
      WBInteraction000347635
      WBInteraction000351938
      WBInteraction000370819
      WBInteraction000389861
      WBInteraction000390225
      WBInteraction000391912
      WBInteraction000397588
      WBInteraction000405009
      WBInteraction000407768
      WBInteraction000409858
      WBInteraction000424648
      WBInteraction000424769
      WBInteraction000429041
      WBInteraction000442868
      WBInteraction000443077
      WBInteraction000448067
      WBInteraction000450780
      WBInteraction000451885
      WBInteraction000462322
      WBInteraction000536364
      WBInteraction000536377
      WBInteraction000536391
      WBInteraction000537154
      WBInteraction000539713
      WBInteraction000551850
      WBInteraction000552816
      WBInteraction000554201
      WBInteraction000559366
      WBInteraction000569427
      WBInteraction000570643
      WBInteraction000573356
      WBInteraction000579543
    WBProcess: WBbiopr:00000012
  Map_info: Map: I Position: 3.01799 Error: 0.000118
    Positive: Positive_clone: K07A12 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Sequence connection from [Iino Y]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene