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WormBase Tree Display for Gene: WBGene00010778

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Name Class

WBGene00010778SMapS_parentSequenceK11H3
IdentityVersion2
NameCGC_namegpdh-2Person_evidenceWBPerson1851
Sequence_nameK11H3.1
Molecular_name (12)
Other_nameCELE_K11H3.1Accession_evidenceNDBBX284603
Public_namegpdh-2
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
212 Sep 2006 10:49:55WBPerson2970Name_changeCGC_namegpdh-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpdh
Allele (77)
StrainWBStrain00003775
WBStrain00032179
WBStrain00048030
RNASeq_FPKM (74)
GO_annotation (26)
Contained_in_operonCEOP3795
Ortholog (48)
ParalogWBGene00009824Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpdh-2 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-2 activity via large-scale RNAi screens results in no obvious defects, expression of a gpdh-2 cDNA in Saccharomyces cerevisiae hog1 mutants is able to rescue the high osmolarity-sensitive growth phenotype of these mutants, suggesting that gpdh-2 encodes a functional glycerol 3-phosphate dehydrogenase.Paper_evidenceWBPaper00003607
Curator_confirmedWBPerson1843
Date_last_updated11 Dec 2006 00:00:00
Automated_descriptionPredicted to enable glycerol-3-phosphate dehydrogenase (quinone) activity and glycerol-3-phosphate dehydrogenase [NAD(P)+] activity. Involved in intracellular accumulation of glycerol. Predicted to be located in cytosol. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Expressed in excretory cell and hypodermis. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Is an ortholog of human GPD1 (glycerol-3-phosphate dehydrogenase 1) and GPD1L (glycerol-3-phosphate dehydrogenase 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110219Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28956)
Molecular_infoCorresponding_CDSK11H3.1a
K11H3.1b
K11H3.1c
K11H3.1d
Corresponding_CDS_historyK11H3.1:wp85
Corresponding_transcriptK11H3.1a.1
K11H3.1b.1
K11H3.1c.1
K11H3.1d.1
Other_sequenceMIC05690_1
FG583129.1
FK806244.1
TV00145
Tcol_isotig05517
RS10010
AYC03638_1
BU087933.1
FC544024.1
Oden_isotig05101
EX557361.1
FC546041.1
ACC18422_1
FK808678.1
FF679816.1
RS10310
FC550121.1
MC04651
EX009578.1
FF679626.1
FK807955.1
AE02469
FK803885.1
EY469729.1
RSC03254_1
MCC00282_1
ACC00574_1
HBC20271_1
BXC01368_1
GO239026.1
Name_isotig02417
GO238890.1
Oden_isotig05111
EX559984.1
Tcol_isotig05519
CSC01799_1
AYC02482_1
CBC04363_1
FE913163.1
GO238902.1
RSC04575_1
EX007054.1
EY465713.1
ACC06834_1
Oden_isotig05104
GO238964.1
FF681946.1
HG02431
GO239002.1
EX537354.1
Oden_isotig05108
ASC38078_1
Tcir_isotig10062
GO238878.1
EX562357.1
EY473349.1
JI168777.1
FK804507.1
GO238970.1
EW743113.1
EX547536.1
EY462092.1
HBC03506_1
EY462832.1
CRC05037_1
NAC00419_1
GO239030.1
GO238997.1
EX565384.1
FC543226.1
EY468189.1
FK805030.1
FC547880.1
Oden_isotig05109
EX565201.1
EX563150.1
Tcol_isotig05518
Oden_isotig05110
GO238914.1
EX563033.1
FC554626.1
Oden_isotig05100
AE03722
Tcol_isotig05520
BXC00038_1
GO238892.1
GO238917.1
ES744009.1
CSC01332_1
ACC19012_1
FC544392.1
EX015073.1
GO251483.1
PVC01609_1
PPC05272_1
MC00107
ACC27730_1
ES672851.1
OOC01707_1
FC553460.1
ACC26554_1
EY463085.1
EX565340.1
FK806950.1
FD516766.1
EX560747.1
GO238905.1
CV200936.1
GRC05459_1
Oden_isotig05103
JI171360.1
GR11238
FF681648.1
FC545627.1
BU087647.1
EX556342.1
FK809514.1
BUC00939_1
FK808055.1
GO252366.1
ACC12855_1
EX555685.1
ACC15473_1
BU666257.1
ACC16122_1
AE04194
FC546271.1
GO238975.1
Acan_isotig03556
Oden_isotig05105
EY466041.1
EW743873.1
BU665939.1
GO238915.1
FC555247.1
CR02308
TVC00835_1
EX914852.1
EY463769.1
FF681834.1
FK804456.1
SC00357
GO239004.1
FD517020.1
FF679520.1
EY462579.1
ES672860.1
EX565118.1
HGC05995_1
MI05971
Oden_isotig05102
PPC07545_1
EW743272.1
PPC17466_1
BXC01358_1
MI02091
Oden_isotig05107
JI172093.1
GO238950.1
GO238904.1
GO238980.1
CJC13854_1
DN153032.1
Acan_isotig11738
BXC00857_1
JO471647.1
GO238985.1
GO238895.1
Hbac_isotig01619
Dviv_isotig23680
Oden_isotig05106
FC552297.1
FF679326.1
Acan_isotig03555
GR978767.1
EY469224.1
GO238953.1
EY467748.1
BU088359.1
Associated_feature (14)
Experimental_infoRNAi_resultWBRNAi00034302Inferred_automaticallyRNAi_primary
WBRNAi00092280Inferred_automaticallyRNAi_primary
WBRNAi00050633Inferred_automaticallyRNAi_primary
WBRNAi00017038Inferred_automaticallyRNAi_primary
WBRNAi00092279Inferred_automaticallyRNAi_primary
WBRNAi00006047Inferred_automaticallyRNAi_primary
Expr_patternExpr3987
Expr6392
Expr1018067
Expr1034717
Expr1154341
Expr2012210
Expr2030446
Drives_constructWBCnstr00004195
WBCnstr00011798
WBCnstr00031154
Construct_productWBCnstr00031154
Microarray_results (34)
Expression_cluster (151)
InteractionWBInteraction000032158
WBInteraction000047771
WBInteraction000047772
WBInteraction000047817
WBInteraction000106596
WBInteraction000111799
WBInteraction000112466
WBInteraction000114204
WBInteraction000121941
WBInteraction000133031
WBInteraction000135672
WBInteraction000137147
WBInteraction000138459
WBInteraction000141424
WBInteraction000142465
WBInteraction000146690
WBInteraction000151901
WBInteraction000156192
WBInteraction000168674
WBInteraction000170413
WBInteraction000175730
WBInteraction000180030
WBInteraction000187697
WBInteraction000201735
WBInteraction000202465
WBInteraction000209896
WBInteraction000211709
WBInteraction000214865
WBInteraction000218092
WBInteraction000222202
WBInteraction000222968
WBInteraction000227945
WBInteraction000233825
WBInteraction000234775
WBInteraction000239060
WBInteraction000252661
WBInteraction000264986
WBInteraction000264987
WBInteraction000281504
WBInteraction000298862
WBInteraction000301312
WBInteraction000328430
WBInteraction000341072
WBInteraction000341096
WBInteraction000354242
WBInteraction000362433
WBInteraction000362874
WBInteraction000369153
WBInteraction000371227
WBInteraction000376728
WBInteraction000380221
WBInteraction000381782
WBInteraction000405207
WBInteraction000407617
WBInteraction000407618
WBInteraction000411196
WBInteraction000417740
WBInteraction000418061
WBInteraction000421352
WBInteraction000434779
WBInteraction000437899
WBInteraction000441005
WBInteraction000445011
WBInteraction000455150
WBInteraction000458513
WBInteraction000459729
WBInteraction000459819
WBInteraction000463410
WBInteraction000463905
WBInteraction000465108
WBInteraction000465985
WBInteraction000467070
WBInteraction000467122
WBInteraction000468950
WBInteraction000470527
WBInteraction000470645
WBInteraction000472186
WBInteraction000472187
WBInteraction000472319
WBInteraction000472910
WBInteraction000473484
WBInteraction000473607
WBInteraction000474070
WBInteraction000474220
WBInteraction000474457
WBInteraction000474574
WBInteraction000474649
WBInteraction000475179
WBInteraction000475216
WBInteraction000475341
WBInteraction000500646
WBInteraction000501506
WBInteraction000503555
WBInteraction000519364
WBInteraction000540522
WBInteraction000551672
WBInteraction000554392
WBInteraction000558461
WBInteraction000559392
WBInteraction000560537
WBInteraction000562894
WBInteraction000563910
WBInteraction000566029
WBInteraction000566357
WBInteraction000566636
WBInteraction000568783
WBInteraction000572055
WBInteraction000576162
WBInteraction000580724
WBInteraction000583257
WBInteraction000586053
Map_infoMapIIIPosition1.12662Error0.001222
PositivePositive_cloneK11H3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene