WormBase Tree Display for Gene: WBGene00003917

WBGene00003917 SMap: S_parent: Sequence: F58B6
  Identity: Version: 2
    Name: CGC_name: par-2 Person_evidence: WBPerson314
      Sequence_name: F58B6.3
      Molecular_name (19)
      Other_name: CELE_F58B6.3 Accession_evidence: NDB BX284603
      Public_name: par-2
    DB_info: Database: AceView gene 3C183
        WormQTL gene WBGene00003917
        WormFlux gene WBGene00003917
        NDB locus_tag CELE_F58B6.3
        Panther gene CAEEL|WormBase=WBGene00003917|UniProtKB=Q965F9
          family PTHR44080
        NCBI gene 175275
        RefSeq protein NM_001420607.1
            NM_001027459.7
            NM_001420609.1
            NM_001420606.1
            NM_001381725.1
        TrEMBL UniProtAcc A0A8S4SQT8
            A0A8S4SL65
            A0A8S4SK97
            H1ZUX3
            Q965F9
        UniProt_GCRP UniProtAcc A0A8S4SQT8
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 02 Jan 2022 21:17:43 WBPerson1983 Event: Split_into: WBGene00306125
      Split_into: WBGene00306125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: par
    Allele (329)
    Legacy_information: it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless).
      See also e2030
      [C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK]
    Strain (17)
    RNASeq_FPKM (74)
    GO_annotation (26)
    Contained_in_operon: CEOP3056
    Ortholog (22)
    Structured_description: Concise_description: par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. Paper_evidence: WBPaper00005115
            WBPaper00005317
            WBPaper00005405
            WBPaper00005575
            WBPaper00005735
            WBPaper00005778
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F58B6.3a
      F58B6.3b
      F58B6.3c
      F58B6.3d
      F58B6.3e
    Corresponding_CDS_history: F58B6.3:wp19
      F58B6.3a:wp229
      F58B6.3a:wp283
      F58B6.3b:wp150
    Corresponding_transcript: F58B6.3a.1
      F58B6.3b.1
      F58B6.3c.1
      F58B6.3d.1
      F58B6.3e.1
      F58B6.3e.2
      F58B6.3e.3
      F58B6.3e.4
      F58B6.3e.5
    Other_sequence: CR05646
      CRC02017_1
      MPC00003_1
    Associated_feature (14)
  Experimental_info: RNAi_result (96)
    Expr_pattern (11)
    Drives_construct: WBCnstr00009161
      WBCnstr00009162
      WBCnstr00009163
      WBCnstr00009164
      WBCnstr00009165
      WBCnstr00009166
      WBCnstr00009167
      WBCnstr00009168
      WBCnstr00009170
    Construct_product (13)
    Antibody (11)
    Microarray_results (23)
    Expression_cluster (108)
    Interaction: WBInteraction000000118
      WBInteraction000000267
      WBInteraction000000427
      WBInteraction000000435
      WBInteraction000000436
      WBInteraction000000784
      WBInteraction000001351
      WBInteraction000001352
      WBInteraction000001371
      WBInteraction000001372
      WBInteraction000002292
      WBInteraction000003101
      WBInteraction000003151
      WBInteraction000003152
      WBInteraction000003324
      WBInteraction000003325
      WBInteraction000003575
      WBInteraction000003576
      WBInteraction000003577
      WBInteraction000003578
      WBInteraction000003579
      WBInteraction000003580
      WBInteraction000003668
      WBInteraction000003669
      WBInteraction000003670
      WBInteraction000003671
      WBInteraction000003672
      WBInteraction000003673
      WBInteraction000005209
      WBInteraction000005210
      WBInteraction000006412
      WBInteraction000006508
      WBInteraction000006590
      WBInteraction000006968
      WBInteraction000007680
      WBInteraction000008831
      WBInteraction000008832
      WBInteraction000008833
      WBInteraction000008834
      WBInteraction000008835
      WBInteraction000008836
      WBInteraction000008837
      WBInteraction000008838
      WBInteraction000008839
      WBInteraction000009119
      WBInteraction000009120
      WBInteraction000009121
      WBInteraction000009122
      WBInteraction000009123
      WBInteraction000009124
      WBInteraction000009125
      WBInteraction000009126
      WBInteraction000009127
      WBInteraction000009128
      WBInteraction000009129
      WBInteraction000009130
      WBInteraction000009131
      WBInteraction000009132
      WBInteraction000009133
      WBInteraction000009134
      WBInteraction000009135
      WBInteraction000009136
      WBInteraction000009137
      WBInteraction000009138
      WBInteraction000009139
      WBInteraction000009140
      WBInteraction000009141
      WBInteraction000009142
      WBInteraction000009143
      WBInteraction000009144
      WBInteraction000009145
      WBInteraction000009146
      WBInteraction000009147
      WBInteraction000009148
      WBInteraction000009149
      WBInteraction000009150
      WBInteraction000009151
      WBInteraction000009152
      WBInteraction000009153
      WBInteraction000009154
      WBInteraction000009155
      WBInteraction000009156
      WBInteraction000009437
      WBInteraction000009438
      WBInteraction000009439
      WBInteraction000009697
      WBInteraction000028317
      WBInteraction000028379
      WBInteraction000029221
      WBInteraction000043508
      WBInteraction000050855
      WBInteraction000050882
      WBInteraction000050883
      WBInteraction000050884
      WBInteraction000051962
      WBInteraction000052870
      WBInteraction000052871
      WBInteraction000126259
      WBInteraction000126402
      WBInteraction000126434
      WBInteraction000126475
      WBInteraction000126681
      WBInteraction000127080
      WBInteraction000127395
      WBInteraction000134412
      WBInteraction000134413
      WBInteraction000134955
      WBInteraction000135835
      WBInteraction000135837
      WBInteraction000139145
      WBInteraction000152334
      WBInteraction000166169
      WBInteraction000168346
      WBInteraction000168349
      WBInteraction000168350
      WBInteraction000182398
      WBInteraction000182399
      WBInteraction000182400
      WBInteraction000182401
      WBInteraction000182402
      WBInteraction000182403
      WBInteraction000182404
      WBInteraction000182405
      WBInteraction000192336
      WBInteraction000192337
      WBInteraction000207038
      WBInteraction000207039
      WBInteraction000207040
      WBInteraction000211497
      WBInteraction000211498
      WBInteraction000215319
      WBInteraction000215320
      WBInteraction000215321
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      WBInteraction000230231
      WBInteraction000250196
      WBInteraction000250197
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      WBInteraction000250199
      WBInteraction000250200
      WBInteraction000250201
      WBInteraction000250202
      WBInteraction000250203
      WBInteraction000257139
      WBInteraction000257140
      WBInteraction000263942
      WBInteraction000279890
      WBInteraction000279891
      WBInteraction000279892
      WBInteraction000281682
      WBInteraction000281683
      WBInteraction000283835
      WBInteraction000329646
      WBInteraction000330302
      WBInteraction000337120
      WBInteraction000337121
      WBInteraction000337122
      WBInteraction000337847
      WBInteraction000362341
      WBInteraction000362342
      WBInteraction000370298
      WBInteraction000370299
      WBInteraction000370300
      WBInteraction000370301
      WBInteraction000380858
      WBInteraction000386821
      WBInteraction000392301
      WBInteraction000404111
      WBInteraction000412803
      WBInteraction000412804
      WBInteraction000415178
      WBInteraction000437514
      WBInteraction000460214
      WBInteraction000463642
      WBInteraction000464919
      WBInteraction000464920
      WBInteraction000469378
      WBInteraction000472212
      WBInteraction000474248
      WBInteraction000474700
      WBInteraction000474701
      WBInteraction000474702
      WBInteraction000474703
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      WBInteraction000474706
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      WBInteraction000474708
      WBInteraction000500946
      WBInteraction000500947
      WBInteraction000500948
      WBInteraction000500949
      WBInteraction000500950
      WBInteraction000501374
      WBInteraction000501386
      WBInteraction000501404
      WBInteraction000501433
      WBInteraction000501434
      WBInteraction000501547
      WBInteraction000501548
      WBInteraction000501662
      WBInteraction000501761
      WBInteraction000501802
      WBInteraction000501805
      WBInteraction000501986
      WBInteraction000502574
      WBInteraction000502581
      WBInteraction000502654
      WBInteraction000502663
      WBInteraction000502672
      WBInteraction000502673
      WBInteraction000502850
      WBInteraction000502878
      WBInteraction000503019
      WBInteraction000503393
      WBInteraction000503440
      WBInteraction000503509
      WBInteraction000503526
      WBInteraction000503531
      WBInteraction000503567
      WBInteraction000503737
      WBInteraction000503962
      WBInteraction000504197
      WBInteraction000504199
      WBInteraction000504507
      WBInteraction000504508
      WBInteraction000504510
      WBInteraction000504856
      WBInteraction000504989
      WBInteraction000504990
      WBInteraction000517736
      WBInteraction000518445
      WBInteraction000518925
      WBInteraction000518990
      WBInteraction000521587
      WBInteraction000525087
      WBInteraction000525088
      WBInteraction000534869
      WBInteraction000539110
      WBInteraction000539111
      WBInteraction000539112
      WBInteraction000539113
      WBInteraction000539114
      WBInteraction000539115
      WBInteraction000539116
      WBInteraction000539117
      WBInteraction000539118
      WBInteraction000539119
      WBInteraction000539120
      WBInteraction000539121
      WBInteraction000539122
      WBInteraction000539123
      WBInteraction000539124
      WBInteraction000539125
      WBInteraction000539126
      WBInteraction000539127
      WBInteraction000539128
      WBInteraction000539129
      WBInteraction000539130
      WBInteraction000539131
      WBInteraction000539132
      WBInteraction000539133
      WBInteraction000539134
      WBInteraction000539135
      WBInteraction000539136
      WBInteraction000539137
      WBInteraction000539138
      WBInteraction000539139
      WBInteraction000539140
      WBInteraction000539141
      WBInteraction000539142
      WBInteraction000539143
      WBInteraction000539144
      WBInteraction000539145
      WBInteraction000539146
      WBInteraction000539147
      WBInteraction000539148
      WBInteraction000539149
      WBInteraction000539150
      WBInteraction000539151
      WBInteraction000539152
      WBInteraction000539153
      WBInteraction000539154
      WBInteraction000539155
      WBInteraction000539156
      WBInteraction000539157
      WBInteraction000539158
      WBInteraction000539159
      WBInteraction000539160
      WBInteraction000539161
      WBInteraction000539162
      WBInteraction000539163
      WBInteraction000539164
      WBInteraction000539165
      WBInteraction000539166
      WBInteraction000539167
      WBInteraction000539168
      WBInteraction000539169
      WBInteraction000539170
      WBInteraction000539171
      WBInteraction000539172
      WBInteraction000539173
      WBInteraction000539174
      WBInteraction000539175
      WBInteraction000539176
      WBInteraction000539177
      WBInteraction000539178
      WBInteraction000539179
      WBInteraction000539180
      WBInteraction000539181
      WBInteraction000539182
      WBInteraction000539183
      WBInteraction000539184
      WBInteraction000539185
      WBInteraction000539186
      WBInteraction000539187
      WBInteraction000539188
      WBInteraction000539189
      WBInteraction000539190
      WBInteraction000539191
      WBInteraction000539192
      WBInteraction000539193
      WBInteraction000539194
      WBInteraction000539195
      WBInteraction000539196
      WBInteraction000541570
      WBInteraction000541573
      WBInteraction000541682
      WBInteraction000541683
      WBInteraction000541725
      WBInteraction000541903
      WBInteraction000541904
      WBInteraction000541905
      WBInteraction000543883
      WBInteraction000543943
      WBInteraction000543944
      WBInteraction000543945
      WBInteraction000543946
      WBInteraction000543947
      WBInteraction000555268
      WBInteraction000555277
      WBInteraction000555291
      WBInteraction000555495
      WBInteraction000555748
      WBInteraction000556158
      WBInteraction000556160
      WBInteraction000556627
      WBInteraction000556994
      WBInteraction000556995
      WBInteraction000556996
      WBInteraction000556997
      WBInteraction000557485
      WBInteraction000557486
      WBInteraction000557487
      WBInteraction000557488
      WBInteraction000557489
      WBInteraction000557491
      WBInteraction000557492
      WBInteraction000557494
      WBInteraction000557495
      WBInteraction000557514
      WBInteraction000558148
      WBInteraction000558152
      WBInteraction000558168
      WBInteraction000558307
      WBInteraction000558329
      WBInteraction000558330
      WBInteraction000575601
      WBInteraction000579140
      WBInteraction000579141
    WBProcess: WBbiopr:00000017
  Map_info: Map: III Position: -23.7021 Error: 0.225136
    Well_ordered
    Positive: Positive_clone: F58B6 Inferred_automatically: From sequence, transcript, pseudogene data
        Y11F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 2720
        2721
        4699
      Multi_point: 1087
        1088
        1409
        1578
        1580
        1629
        1630
        1632
        5299
        5497
        5543
    Landmark_gene
  Reference (312)
  Method: Gene