WormBase Tree Display for Gene: WBGene00006381

WBGene00006381 SMap: S_parent: Sequence: Y54E2A
  Identity: Version: 1
    Name: CGC_name: tac-1 Person_evidence: WBPerson208
      Sequence_name: Y54E2A.3
      Molecular_name: Y54E2A.3
        Y54E2A.3.1
        CE20302
      Other_name: 2P40 Accession_evidence: EMBL AF326937
        CELE_Y54E2A.3 Accession_evidence: NDB BX284602
      Public_name: tac-1
    DB_info: Database: AceView gene 2P38
        WormQTL gene WBGene00006381
        WormFlux gene WBGene00006381
        NDB locus_tag CELE_Y54E2A.3
        NCBI gene 175133
        RefSeq protein NM_064658.8
        SwissProt UniProtAcc G5ECG0
        UniProt_GCRP UniProtAcc G5ECG0
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tac
    Allele (20)
    Strain: WBStrain00037424
      WBStrain00007335
      WBStrain00007333
      WBStrain00050672
    RNASeq_FPKM (74)
    GO_annotation (46)
    Contained_in_operon: CEOP2648
    Ortholog (20)
    Structured_description: Concise_description: tac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm. Paper_evidence: WBPaper00006059
            WBPaper00006060
            WBPaper00006061
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Mar 2006 00:00:00
      Automated_description: Enables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y54E2A.3
    Corresponding_transcript: Y54E2A.3.1
    Other_sequence: AF326937
      FG620567.1
    Associated_feature: WBsf650765
      WBsf224306
  Experimental_info: RNAi_result (18)
    Expr_pattern: Expr2681
      Expr2683
      Expr2684
      Expr2685
      Expr12439
      Expr1020108
      Expr1032578
      Expr1160809
      Expr2017202
      Expr2035338
    Construct_product: WBCnstr00005024
      WBCnstr00010900
      WBCnstr00015616
      WBCnstr00015617
      WBCnstr00020876
      WBCnstr00021102
      WBCnstr00022253
      WBCnstr00022255
      WBCnstr00022258
      WBCnstr00040176
    Antibody: WBAntibody00000668
      WBAntibody00000669
      WBAntibody00000670
      WBAntibody00002182
      WBAntibody00002963
      WBAntibody00003043
    Microarray_results: SMD_Y54E2A.3
      181770_s_at
      A_12_P107046
      Aff_Y54E2A.3
      GPL13394_WBGene00006381
      GPL13914_Y54E2A.3
      GPL14144_Y54E2A.3_250-309_0.936_5_B
      GPL14144_Y54E2A.3_505-564_0.866_13_C
      GPL14144_Y54E2A.3_638-697_0.958_1_A
      GPL19516_CGZ0049058
      GPL21109_Y54E2A.3
      GPL3518_CE20302
      GPL8304_CE_WBGene00006381_A
      GPL8673_Y54E2A_3P00120
      GPL8673_Y54E2A_3P00250
      GPL8673_Y54E2A_3P00432
      GPL9450_Y54E2A.3
      cea2.c.15529
    Expression_cluster (114)
    Interaction: WBInteraction000009606
      WBInteraction000028322
      WBInteraction000028590
      WBInteraction000028599
      WBInteraction000028611
      WBInteraction000028925
      WBInteraction000029098
      WBInteraction000029292
      WBInteraction000031594
      WBInteraction000031817
      WBInteraction000031818
      WBInteraction000052760
      WBInteraction000126455
      WBInteraction000126772
      WBInteraction000138006
      WBInteraction000138007
      WBInteraction000147226
      WBInteraction000152592
      WBInteraction000171308
      WBInteraction000217970
      WBInteraction000218137
      WBInteraction000218138
      WBInteraction000220620
      WBInteraction000231108
      WBInteraction000233365
      WBInteraction000252678
      WBInteraction000287587
      WBInteraction000300080
      WBInteraction000301187
      WBInteraction000335944
      WBInteraction000343535
      WBInteraction000349074
      WBInteraction000363492
      WBInteraction000367376
      WBInteraction000370654
      WBInteraction000373118
      WBInteraction000373228
      WBInteraction000373990
      WBInteraction000383514
      WBInteraction000384149
      WBInteraction000384230
      WBInteraction000384563
      WBInteraction000384724
      WBInteraction000398400
      WBInteraction000404450
      WBInteraction000413311
      WBInteraction000415405
      WBInteraction000416532
      WBInteraction000433384
      WBInteraction000433445
      WBInteraction000439635
      WBInteraction000446450
      WBInteraction000447002
      WBInteraction000501448
      WBInteraction000501449
      WBInteraction000501450
      WBInteraction000501451
      WBInteraction000501452
      WBInteraction000501453
      WBInteraction000501454
      WBInteraction000501455
      WBInteraction000501456
      WBInteraction000501457
      WBInteraction000501458
      WBInteraction000508040
      WBInteraction000510149
      WBInteraction000510174
      WBInteraction000510223
      WBInteraction000510236
      WBInteraction000510237
      WBInteraction000510262
      WBInteraction000510838
      WBInteraction000513298
      WBInteraction000513299
      WBInteraction000513301
      WBInteraction000513305
      WBInteraction000513308
      WBInteraction000514840
      WBInteraction000514841
      WBInteraction000514842
      WBInteraction000515428
      WBInteraction000515431
      WBInteraction000515888
      WBInteraction000515890
      WBInteraction000515892
      WBInteraction000515894
      WBInteraction000515895
      WBInteraction000515896
      WBInteraction000516749
      WBInteraction000516756
      WBInteraction000516761
      WBInteraction000516762
      WBInteraction000516943
      WBInteraction000516966
      WBInteraction000516984
      WBInteraction000522239
      WBInteraction000522859
      WBInteraction000522995
      WBInteraction000522996
      WBInteraction000522997
      WBInteraction000522998
      WBInteraction000522999
      WBInteraction000523000
      WBInteraction000523001
      WBInteraction000523002
      WBInteraction000523003
      WBInteraction000523004
      WBInteraction000523005
      WBInteraction000523079
      WBInteraction000523131
      WBInteraction000523162
      WBInteraction000523300
      WBInteraction000523314
      WBInteraction000523445
      WBInteraction000523482
      WBInteraction000523563
      WBInteraction000534803
      WBInteraction000539514
      WBInteraction000540526
      WBInteraction000540528
      WBInteraction000542777
      WBInteraction000543635
      WBInteraction000543698
      WBInteraction000543907
      WBInteraction000543936
      WBInteraction000544005
      WBInteraction000546030
      WBInteraction000546863
      WBInteraction000547014
      WBInteraction000547188
      WBInteraction000547465
      WBInteraction000547963
      WBInteraction000547987
      WBInteraction000548025
      WBInteraction000548130
      WBInteraction000548286
      WBInteraction000548344
      WBInteraction000548448
      WBInteraction000548463
      WBInteraction000548675
      WBInteraction000548696
      WBInteraction000550727
      WBInteraction000550751
      WBInteraction000550776
      WBInteraction000554262
      WBInteraction000556294
      WBInteraction000556607
      WBInteraction000559638
      WBInteraction000568708
      WBInteraction000575128
      WBInteraction000578964
      WBInteraction000580430
  Map_info: Map: II Position: 23.4578 Error: 0.010609
    Positive: Positive_clone: Y54E2A Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (35)
  Remark: Sequence connection from [Bellanger J-M, Gonczy P], 02/06/10 krb
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene