WormBase Tree Display for Gene: WBGene00006833
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WBGene00006833 | SMap | S_parent | Sequence | F53F10 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | unc-108 | Person_evidence | WBPerson261 | |||
Sequence_name | F53F10.4 | ||||||
Molecular_name (12) | |||||||
Other_name | rab-2 | ||||||
unc-67 | Person_evidence | WBPerson261 | |||||
CELE_F53F10.4 | Accession_evidence | NDB | BX284601 | ||||
Public_name | unc-108 | ||||||
DB_info | Database | AceView | gene | 1E393 | |||
WormQTL | gene | WBGene00006833 | |||||
WormFlux | gene | WBGene00006833 | |||||
NDB | locus_tag | CELE_F53F10.4 | |||||
Panther | gene | CAEEL|WormBase=WBGene00006833|UniProtKB=A0A2C9C2Y0 | |||||
family | PTHR47979 | ||||||
NCBI | gene | 171956 | |||||
RefSeq | protein | NM_001356805.3 | |||||
NM_001393282.1 | |||||||
NM_001356804.3 | |||||||
NM_001356806.3 | |||||||
TrEMBL | UniProtAcc | A0A2C9C2Y0 | |||||
A0A2C9C3C9 | |||||||
O01577 | |||||||
A0A2C9C379 | |||||||
UniProt_GCRP | UniProtAcc | A0A2C9C2Y0 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Acquires_merge | WBGene00006800 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | unc | ||||||
Reference_allele | WBVar00089559 | ||||||
Allele (58) | |||||||
Legacy_information | n501dm : sluggish poor backing. Similar phenotype in n501/+. ES3. NA1. Possibly haplo-insufficient locus. | ||||||
See also n501, n777 | |||||||
[C.elegansII] n501dm : sluggish, poor backing. Similar phenotype in n501/+. ES3. OA1: n777. Possibly haplo-insufficient locus. [Park and Horvitz 1986a] | |||||||
e713 : sluggish can move well both forward and backward but frequently pauses or jams up. ES2 ME2. NA1. | |||||||
[C.elegansII] e713 : sluggish, can move well both forward and backward but frequently pauses or jams up. ES2 ME2. NA1. [Brenner 1974; MQ] | |||||||
Strain | WBStrain00023643 | ||||||
WBStrain00026794 | |||||||
WBStrain00026882 | |||||||
WBStrain00036101 | |||||||
WBStrain00040847 | |||||||
WBStrain00004200 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (38) | |||||||
Contained_in_operon | CEOP1116 | ||||||
Ortholog (37) | |||||||
Paralog (32) | |||||||
Structured_description | Concise_description | unc-108 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; unc-108 function is required in neurons for normal locomotion; unc-108 also functions in the removal of apoptotic cells, specifically it functions in engulfing cells for the recruitment and fusion of the lysosome to the phagosome; unc-108 is expressed in neurons and in engulfing cells. | Paper_evidence | WBPaper00015788 | |||
WBPaper00031470 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson324 | |||||||
Date_last_updated | 14 Aug 2008 00:00:00 | ||||||
Automated_description | Enables GTPase activity. Involved in several processes, including dense core granule maturation; phagosome maturation involved in apoptotic cell clearance; and regulation of locomotion involved in locomotory behavior. Located in axon; cytoplasm; and neuronal cell body. Expressed in several structures, including excretory gland cell; hermaphrodite somatic gonadal cell; neurons; pharyngeal gland cell; and rectal gland cell. Is an ortholog of human RAB2A (RAB2A, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F53F10.4a | |||||
F53F10.4b | |||||||
F53F10.4c | |||||||
F53F10.4d | |||||||
Corresponding_transcript | F53F10.4a.1 | ||||||
F53F10.4b.1 | |||||||
F53F10.4c.1 | |||||||
F53F10.4d.1 | |||||||
Other_sequence (24) | |||||||
Associated_feature (11) | |||||||
Experimental_info | RNAi_result (40) | ||||||
Expr_pattern (16) | |||||||
Drives_construct | WBCnstr00002664 | ||||||
WBCnstr00005792 | |||||||
WBCnstr00005793 | |||||||
WBCnstr00013020 | |||||||
WBCnstr00013022 | |||||||
WBCnstr00013277 | |||||||
WBCnstr00013541 | |||||||
WBCnstr00019190 | |||||||
WBCnstr00034128 | |||||||
Construct_product (21) | |||||||
Antibody | WBAntibody00001993 | ||||||
WBAntibody00001994 | |||||||
Microarray_results (28) | |||||||
Expression_cluster (143) | |||||||
Interaction (51) | |||||||
WBProcess | WBbiopr:00000013 | ||||||
WBbiopr:00000015 | |||||||
Map_info | Map | I | Position | -2.00793 | Error | 0.05662 | |
Positive | Positive_clone | F53F10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
From CDS info | |||||||
Mapping_data | 2_point | 59 | |||||
80 | |||||||
489 | |||||||
490 | |||||||
Multi_point (7) | |||||||
Pos_neg_data | 363 | ||||||
Reference (55) | |||||||
Method | Gene |