WormBase Tree Display for Gene: WBGene00006833
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WBGene00006833 | SMap | S_parent | Sequence | F53F10 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | unc-108 | Person_evidence | WBPerson261 | |||||
Sequence_name | F53F10.4 | ||||||||
Molecular_name (12) | |||||||||
Other_name | rab-2 | ||||||||
unc-67 | Person_evidence | WBPerson261 | |||||||
CELE_F53F10.4 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | unc-108 | ||||||||
DB_info | Database (9) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 18 Nov 2008 14:39:11 | WBPerson2970 | Event | Acquires_merge | WBGene00006800 | ||||
Name_change | Other_name | unc-67 | |||||||
Acquires_merge | WBGene00006800 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Reference_allele | WBVar00089559 | ||||||||
Allele (58) | |||||||||
Legacy_information | n501dm : sluggish poor backing. Similar phenotype in n501/+. ES3. NA1. Possibly haplo-insufficient locus. | ||||||||
See also n501, n777 | |||||||||
[C.elegansII] n501dm : sluggish, poor backing. Similar phenotype in n501/+. ES3. OA1: n777. Possibly haplo-insufficient locus. [Park and Horvitz 1986a] | |||||||||
e713 : sluggish can move well both forward and backward but frequently pauses or jams up. ES2 ME2. NA1. | |||||||||
[C.elegansII] e713 : sluggish, can move well both forward and backward but frequently pauses or jams up. ES2 ME2. NA1. [Brenner 1974; MQ] | |||||||||
Strain | WBStrain00023643 | ||||||||
WBStrain00026794 | |||||||||
WBStrain00026882 | |||||||||
WBStrain00036101 | |||||||||
WBStrain00040847 | |||||||||
WBStrain00004200 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (38) | |||||||||
Contained_in_operon | CEOP1116 | ||||||||
Ortholog (37) | |||||||||
Paralog (32) | |||||||||
Structured_description | Concise_description | unc-108 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; unc-108 function is required in neurons for normal locomotion; unc-108 also functions in the removal of apoptotic cells, specifically it functions in engulfing cells for the recruitment and fusion of the lysosome to the phagosome; unc-108 is expressed in neurons and in engulfing cells. | Paper_evidence | WBPaper00015788 | |||||
WBPaper00031470 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson324 | |||||||||
Date_last_updated | 14 Aug 2008 00:00:00 | ||||||||
Automated_description | Enables GTPase activity. Involved in several processes, including dense core granule maturation; phagosome maturation involved in apoptotic cell clearance; and regulation of locomotion involved in locomotory behavior. Located in axon; cytoplasm; and neuronal cell body. Expressed in several structures, including excretory gland cell; hermaphrodite somatic gonadal cell; neurons; pharyngeal gland cell; and rectal gland cell. Is an ortholog of human RAB2A (RAB2A, member RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F53F10.4a | |||||||
F53F10.4b | |||||||||
F53F10.4c | |||||||||
F53F10.4d | |||||||||
Corresponding_transcript | F53F10.4a.1 | ||||||||
F53F10.4b.1 | |||||||||
F53F10.4c.1 | |||||||||
F53F10.4d.1 | |||||||||
Other_sequence (24) | |||||||||
Associated_feature (11) | |||||||||
Experimental_info | RNAi_result (40) | ||||||||
Expr_pattern (16) | |||||||||
Drives_construct | WBCnstr00002664 | ||||||||
WBCnstr00005792 | |||||||||
WBCnstr00005793 | |||||||||
WBCnstr00013020 | |||||||||
WBCnstr00013022 | |||||||||
WBCnstr00013277 | |||||||||
WBCnstr00013541 | |||||||||
WBCnstr00019190 | |||||||||
WBCnstr00034128 | |||||||||
Construct_product (21) | |||||||||
Antibody | WBAntibody00001993 | ||||||||
WBAntibody00001994 | |||||||||
Microarray_results (28) | |||||||||
Expression_cluster (143) | |||||||||
Interaction (51) | |||||||||
WBProcess | WBbiopr:00000013 | ||||||||
WBbiopr:00000015 | |||||||||
Map_info | Map | I | Position | -2.00793 | Error | 0.05662 | |||
Positive | Positive_clone | F53F10 | Inferred_automatically (2) | ||||||
Mapping_data | 2_point | 59 | |||||||
80 | |||||||||
489 | |||||||||
490 | |||||||||
Multi_point | 1290 | ||||||||
1291 | |||||||||
4973 | |||||||||
5623 | |||||||||
380 | |||||||||
381 | |||||||||
1288 | |||||||||
Pos_neg_data | 363 | ||||||||
Reference (55) | |||||||||
Method | Gene |