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WormBase Tree Display for Gene: WBGene00000902

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Name Class

WBGene00000902EvidenceCGC_data_submission
SMapS_parentSequenceF31F6
IdentityVersion1
NameCGC_namedaf-6Person_evidenceWBPerson521
Sequence_nameF31F6.5
Molecular_nameF31F6.5
F31F6.5.1
CE38955
Other_nameptr-7Paper_evidenceWBPaper00010276
Person_evidenceWBPerson576
CELE_F31F6.5Accession_evidenceNDBBX284606
Public_namedaf-6
DB_infoDatabaseAceViewgeneXP511
WormQTLgeneWBGene00000902
WormFluxgeneWBGene00000902
NDBlocus_tagCELE_F31F6.5
PanthergeneCAEEL|WormBase=WBGene00000902|UniProtKB=Q19945
familyPTHR10796
NCBIgene181584
RefSeqproteinNM_078071.8
TREEFAMTREEFAM_IDTF331806
TrEMBLUniProtAccQ19945
UniProt_GCRPUniProtAccQ19945
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdaf
Reference_alleleWBVar00143954
Allele (96)
Legacy_informatione1377 : defective dauer formation (daf-1 daf-2 suppressible) abnormal chemotaxis defective osmotic avoidance poor male mating; abnormal sensory anatomy especially amphidial sheath cells; no FITC uptake by amphids or phasmids. ES1 ME2. NA1.
See also e1377
[C.elegansII] e1377 : defective dauer formation; abnormal chemotaxis; defective osmotic avoidance; poor male mating; abnormal sensory anatomy especially amphidial sheath cells (resembles Che-14); Dyf, no FITC uptake by amphids or phasmids. ES1 ME2. OA6. [Perkins et al. 1986; Starich et al. 1995; DR; SP]
StrainWBStrain00004313
WBStrain00004378
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (33)
Paralog (30)
Structured_descriptionConcise_descriptiondaf-6 encodes a Patched-related protein; daf-6 is required for amphid channel morphogenesis and thus, also for normal morphology of the outer labial sensilla; specifically, daf-6 is required for restricting the amphid sensory compartment diameter; daf-6 mutants display defects in several neuron-mediated functions including dauer larvae formation, chemotaxis, osmotic avoidance, male mating, negative regulation of lifespan, negative regulation of the neuron ASJ's axonal growth late in development, and dye uptake by amphids and phasmids; a DAF-6::GFP is expressed in the amphid sheath and socket cells and in the excretory canal.Paper_evidence (11)
Person_evidenceWBPerson261
Curator_confirmedWBPerson13481
WBPerson1843
WBPerson567
Date_last_updated24 Oct 2011 00:00:00
Automated_descriptionInvolved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of dauer larval development; and regulation of insulin receptor signaling pathway. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including cuticle; excretory system; interfacial epithelial cell; neurons; and vulval cell. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF31F6.5
Corresponding_CDS_historyF31F6.5:wp146
Corresponding_transcriptF31F6.5.1
Other_sequenceMA00829
Dviv_isotig25805
GR13379
GRC01680_1
JI166574.1
Oden_isotig23367
MAC00273_1
Oden_isotig25088
Associated_featureWBsf648771
WBsf663603
WBsf663604
WBsf718778
WBsf718779
WBsf718780
WBsf718781
WBsf1008031
WBsf236735
Experimental_infoRNAi_result (4)
Expr_patternExpr3510
Expr3511
Expr3897
Expr8603
Expr12301
Expr1016907
Expr1030566
Expr1149951
Expr2010781
Expr2029018
Drives_constructWBCnstr00006566
WBCnstr00006567
WBCnstr00006570
WBCnstr00007320
WBCnstr00011443
WBCnstr00011444
WBCnstr00011729
WBCnstr00013396
WBCnstr00037208
Construct_productWBCnstr00000949
WBCnstr00006566
WBCnstr00006567
WBCnstr00006570
WBCnstr00011444
WBCnstr00013396
WBCnstr00022848
WBCnstr00037208
Microarray_results (19)
Expression_cluster (190)
Interaction (66)
Map_infoMapXPosition21.5043Error0.013514
PositivePositive_cloneF31F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point283
419
420
421
Multi_point649
4318
4508
Pos_neg_data2161
2169
2228
8330
Reference (109)
PictureWBPicture0000013046
RemarkPrevious sequence connection to C54A12.1 as well as positive clone C54A12 were incorrect [030311 ck1]
ptr-7 has been merged with this gene following advice of CGC [krb 030512]
This gene previously listed ptr-6 as an other name. This association was probably incorrect and has been removed [krb 030512]
MethodGene