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WormBase Tree Display for Gene: WBGene00004178

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Name Class

WBGene00004178SMapS_parentSequenceD2030
IdentityVersion2
NameCGC_nameprg-1
Sequence_nameD2030.6
Molecular_nameD2030.6
D2030.6.1
CE09083
Other_nameCELE_D2030.6Accession_evidenceNDBBX284601
Public_nameprg-1
DB_infoDatabaseAceViewgene1I162
WormQTLgeneWBGene00004178
WormFluxgeneWBGene00004178
NDBlocus_tagCELE_D2030.6
PanthergeneCAEEL|WormBase=WBGene00004178|UniProtKB=P90786
familyPTHR22891
NCBIgene172515
RefSeqproteinNM_059720.7
TREEFAMTREEFAM_IDTF350431
TrEMBLUniProtAccP90786
UniProt_GCRPUniProtAccP90786
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
205 Nov 2007 17:02:03WBPerson2970EventAcquires_mergeWBGene00008416
Name_changeSequence_nameD2030.6
Acquires_mergeWBGene00008416
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classprg
Allele (63)
Possibly_affected_byWBVar02158857
Strain (21)
In_clusterconserved_RDE-1_cluster
conserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (58)
Paralog (22)
Structured_descriptionConcise_descriptionprg-1 encodes a novel, basic protein that is one of two C. elegans members of the Piwi subfamily of highly conserved Argonaut/Piwi proteins; during development, PRG-1 activity is essential for successful gametogenesis, normal levels of fertility, and accumulation of 21 U-RNAs (piRNAs), small RNAs expressed in the germ line; in addition, PRG-1 appears to act upstream of an siRNA pathway to regulate transposition of the Tc3 DNA transposon; PRG-1 physically interacts with 21 U-RNAs in vivo; PRG-1 localizes to P granules throughout development.Paper_evidenceWBPaper00003335
WBPaper00031903
WBPaper00031961
WBPaper00031962
Curator_confirmedWBPerson1843
Date_last_updated24 Jun 2008 00:00:00
Automated_descriptionEnables 21U-RNA binding activity. Involved in 21U-RNA metabolic process; gamete generation; and positive regulation of mitotic nuclear division. Located in P granule. Expressed in germ line and in male. Is an ortholog of human PIWIL1 (piwi like RNA-mediated gene silencing 1) and PIWIL3 (piwi like RNA-mediated gene silencing 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSD2030.6
Corresponding_transcriptD2030.6.1
Other_sequence (23)
Associated_featureWBsf649331
WBsf664462
WBsf976794
WBsf976795
WBsf976796
WBsf219788
Experimental_infoRNAi_resultWBRNAi00007898Inferred_automaticallyRNAi_primary
WBRNAi00091976Inferred_automaticallyRNAi_primary
WBRNAi00116862Inferred_automaticallyRNAi_primary
WBRNAi00091977Inferred_automaticallyRNAi_primary
WBRNAi00003287Inferred_automaticallyRNAi_primary
WBRNAi00043476Inferred_automaticallyRNAi_primary
WBRNAi00115384Inferred_automaticallyRNAi_primary
WBRNAi00030403Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Construct_product (6)
Regulate_expr_cluster (24)
AntibodyWBAntibody00001434
WBAntibody00001435
WBAntibody00002378
WBAntibody00002379
WBAntibody00002584
Microarray_results (17)
Expression_cluster (165)
Interaction (1008)
Map_infoMapIPosition2.18374Error0.005084
PositivePositive_cloneD2030Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00003335
WBPaper00004349
WBPaper00004772
WBPaper00010716
WBPaper00027261
WBPaper00027475
WBPaper00028800
WBPaper00029257
WBPaper00030538
WBPaper00031903
WBPaper00031961
WBPaper00031962
WBPaper00034363
WBPaper00035890
WBPaper00036973
WBPaper00038491
WBPaper00038888
WBPaper00039033
WBPaper00039752
WBPaper00039754
WBPaper00039769
WBPaper00040542
WBPaper00041239
WBPaper00041240
WBPaper00041354
WBPaper00042613
WBPaper00042992
WBPaper00042999
WBPaper00043989
WBPaper00044603
WBPaper00045058
WBPaper00045217
WBPaper00045316
WBPaper00045741
WBPaper00045790
WBPaper00046160
WBPaper00046742
WBPaper00047220
WBPaper00047231
WBPaper00047240
WBPaper00047434
WBPaper00048437
WBPaper00049279
WBPaper00050362
WBPaper00050959
WBPaper00051891
WBPaper00051892
WBPaper00051893
WBPaper00051963
WBPaper00052317
WBPaper00052333
WBPaper00052440
WBPaper00052469
WBPaper00052541
WBPaper00052922
WBPaper00053754
WBPaper00053968
WBPaper00054282
WBPaper00055090
WBPaper00055600
WBPaper00056868
WBPaper00056904
WBPaper00057161
WBPaper00057162
WBPaper00057700
WBPaper00058181
WBPaper00058210
WBPaper00058220
WBPaper00058224
WBPaper00058388
WBPaper00058421
WBPaper00059254
WBPaper00059533
WBPaper00059605
WBPaper00059753
WBPaper00060139
WBPaper00060506
WBPaper00060526
WBPaper00060750
WBPaper00061147
WBPaper00061829
WBPaper00062234
WBPaper00062457
WBPaper00062465
WBPaper00062532
WBPaper00062585
WBPaper00062691
WBPaper00062733
WBPaper00063512
WBPaper00063533
WBPaper00063539
WBPaper00063553
WBPaper00063558
WBPaper00063564
WBPaper00063882
WBPaper00063892
WBPaper00063903
WBPaper00064339
WBPaper00064472
WBPaper00065028
WBPaper00065358
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene