Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00005018

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00005018SMapS_parentSequenceF23H12
IdentityVersion2
NameCGC_namesqt-3Person_evidenceWBPerson153
Sequence_nameF23H12.4
Molecular_nameF23H12.4a
F23H12.4a.1
CE05707
F23H12.4b
CE46560
F23H12.4b.1
Other_namecol-1
dpy-15
rol-4Paper_evidenceWBPaper00024637
Person_evidenceWBPerson261
Rol
CELE_F23H12.4Accession_evidenceNDBBX284605
Public_namesqt-3
DB_infoDatabaseAceViewgene5M833
WormQTLgeneWBGene00005018
WormFluxgeneWBGene00005018
NDBlocus_tagCELE_F23H12.4
PanthergeneCAEEL|WormBase=WBGene00005018|UniProtKB=P08124
familyPTHR24637
NCBIgene179693
RefSeqproteinNM_001269484.3
NM_001269483.3
SwissProtUniProtAccP08124
TrEMBLUniProtAccH2L2C4
UniProt_GCRPUniProtAccP08124
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:37WBPerson1971EventImportedInitial conversion from geneace
223 Aug 2005 10:47:27WBPerson2970EventAcquires_mergeWBGene00004396
Name_changeOther_namerol-4
Acquires_mergeWBGene00004396
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsqt
Reference_alleleWBVar00242688
Allele (64)
Possibly_affected_byWBVar02157913
WBVar02157914
WBVar02157915
WBVar02157916
WBVar02157917
Legacy_informationsc63ts : homozygotes at 25x are non-roller dumpy heterozygotes sc63/+ are non-dumpy left-handed roller in adult high penetrance deformed tail at 25x. ES3 ME0 (25x). At 15x slightly dumpy. NA > 8 (sc80ts (resembles sc63) e24sd ts (pka dpy-15 : dumpy inviable at 25x e24/+ dumpy at 25x) etc.).
See sqt-3.
See also e24, e2117
[C.elegansII] sc63ts,sd : homozygotes at 25C are non-roller dumpy, heterozygotes sc63/+ are non-dumpy left-handed roller in adult; high penetrance deformed tail at 25C. ES3 ME0 (25C). At 15C slightly dumpy. OA3: sc80ts (resembles sc63), e24sd,ts (pka dpy-15, dumpy inviable at 25C, e24/+ dumpy at 25C, sometimes Lon at15C), sc42 (recessive left roller), e2117ts (extreme dumpy early larval lethal at 25C). Cloned: encodes 295 aa collagen (pka col-1), dpy-13 family; mutations all missense; expressed at each larval stage, 4 - 2.5 hours before lethargus. [Kramer et al. 1982; Keyl et al. 1994; IA]
sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. NA3 (b238ts : at 25x rolls only in adult at 16x wildtype).
[C.elegansII] sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. OA2: b238ts (at 25C rolls only in adult, WT at 16C). [Cox et al. 1980]
Strain (23)
RNASeq_FPKM (74)
GO_annotation00023410
00023411
00023412
00023413
00038921
00038922
00038923
00038924
00038925
00113426
Ortholog (27)
Paralog (163)
Structured_descriptionConcise_descriptionsqt-3 encodes a cuticle collagen; during development, sqt-3 activity is essential for viability and normal body morphology; genetic and expression studies indicate that SQT-3 is a cuticle component at all stages of development and that SQT-3 likely forms higher order cuticular structures with the DPY-17 cuticular collagen, both of which are candidate substrates for the DPY-31 procollagen C-proteinase.Paper_evidenceWBPaper00000906
WBPaper00000927
WBPaper00002030
WBPaper00024637
WBPaper00027067
Curator_confirmedWBPerson1843
Date_last_updated27 Mar 2007 00:00:00
Automated_descriptionPredicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23H12.4a
F23H12.4b
Corresponding_transcriptF23H12.4a.1
F23H12.4b.1
Other_sequence (112)
Associated_feature (12)
Experimental_infoRNAi_result (17)
Expr_patternExpr609
Expr617
Expr751
Expr4986
Expr1012789
Expr1032501
Expr1149371
Expr2016118
Expr2034353
Drives_constructWBCnstr00035264
Construct_productWBCnstr00035264
AntibodyWBAntibody00001056
Microarray_results (24)
Expression_cluster (372)
Interaction (234)
WBProcessWBbiopr:00000124
Map_infoMapVPosition4.00808Error0.002342
Well_ordered
PositivePositive_cloneF23H12Inferred_automaticallyFrom sequence, transcript, pseudogene data
ZC348
Mapping_data2_point (13)
Multi_point227
303
304
305
478
526
662
663
664
668
669
942
946
949
1175
1177
1532
1840
1841
1913
2054
2264
2265
2403
2404
2435
2436
2781
2805
2816
3024
3491
5284
5483
5675
5725
261
650
655
665
1161
1162
1164
1165
1166
1179
1180
1435
1525
1786
2161
2162
2163
2164
2165
2166
2405
2797
2798
2806
3099
3100
3360
3362
3395
3421
3644
3848
3878
3962
3963
Pos_neg_data1745
1750
1755
4300
6870
7396
1758
Landmark_gene
ReferenceWBPaper00000031
WBPaper00000465
WBPaper00000569
WBPaper00000608
WBPaper00000722
WBPaper00000746
WBPaper00000748
WBPaper00000763
WBPaper00000806
WBPaper00000875
WBPaper00000906
WBPaper00000927
WBPaper00000942
WBPaper00001099
WBPaper00001101
WBPaper00001146
WBPaper00001211
WBPaper00001212
WBPaper00001261
WBPaper00001280
WBPaper00001322
WBPaper00001323
WBPaper00001328
WBPaper00001392
WBPaper00001439
WBPaper00001493
WBPaper00001515
WBPaper00001542
WBPaper00001567
WBPaper00001582
WBPaper00001618
WBPaper00001639
WBPaper00001692
WBPaper00001709
WBPaper00001738
WBPaper00001799
WBPaper00001835
WBPaper00001918
WBPaper00001922
WBPaper00001927
WBPaper00002006
WBPaper00002030
WBPaper00002448
WBPaper00002512
WBPaper00003289
WBPaper00003348
WBPaper00003853
WBPaper00004438
WBPaper00004883
WBPaper00005272
WBPaper00005704
WBPaper00005747
WBPaper00005815
WBPaper00006361
WBPaper00006388
WBPaper00006422
WBPaper00011521
WBPaper00011769
WBPaper00011971
WBPaper00012717
WBPaper00013730
WBPaper00013732
WBPaper00013735
WBPaper00013780
WBPaper00013879
WBPaper00013884
WBPaper00013885
WBPaper00013992
WBPaper00014004
WBPaper00014048
WBPaper00014087
WBPaper00014101
WBPaper00014137
WBPaper00014289
WBPaper00014296
WBPaper00014311
WBPaper00014351
WBPaper00014385
WBPaper00014424
WBPaper00014457
WBPaper00014490
WBPaper00014494
WBPaper00014557
WBPaper00014652
WBPaper00014662
WBPaper00014687
WBPaper00014788
WBPaper00014968
WBPaper00015004
WBPaper00015061
WBPaper00015217
WBPaper00015273
WBPaper00015338
WBPaper00015362
WBPaper00015367
WBPaper00015510
WBPaper00015522
WBPaper00015821
WBPaper00015832
WBPaper00015974
WBPaper00016149
WBPaper00016210
WBPaper00016227
WBPaper00016238
WBPaper00016290
WBPaper00016362
WBPaper00016456
WBPaper00016504
WBPaper00016535
WBPaper00016590
WBPaper00016936
WBPaper00017210
WBPaper00017931
WBPaper00018144
WBPaper00018954
WBPaper00020839
WBPaper00020873
WBPaper00021003
WBPaper00021117
WBPaper00021855
WBPaper00022463
WBPaper00022487
WBPaper00022979
WBPaper00023185
WBPaper00023275
WBPaper00023413
WBPaper00024637
WBPaper00024840
WBPaper00025032
WBPaper00025380
WBPaper00025566
WBPaper00026198
WBPaper00026480
WBPaper00027067
WBPaper00027237
WBPaper00027244
WBPaper00027253
WBPaper00030802
WBPaper00032033
WBPaper00032230
WBPaper00035199
WBPaper00035463
WBPaper00037548
WBPaper00040146
WBPaper00042248
WBPaper00042851
WBPaper00051849
WBPaper00055356
WBPaper00059378
WBPaper00061118
WBPaper00061301
WBPaper00061547
WBPaper00061662
WBPaper00062982
WBPaper00063275
WBPaper00064788
WBPaper00065859
WBPaper00066006
WBPaper00066030
MethodGene